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The map label for this gene is dsdA

Identifier: 222110819

GI number: 222110819

Start: 1713173

End: 1714528

Strand: Direct

Name: dsdA

Synonym: Dtpsy_1624

Alternate gene names: 222110819

Gene position: 1713173-1714528 (Clockwise)

Preceding gene: 222110815

Following gene: 222110820

Centisome position: 45.12

GC content: 70.8

Gene sequence:

>1356_bases
ATGCCCTCCGTTGTTTCCCCACAGGACCGCTTGCAGGACGACGCCCCGGCTGCACAACTGCGCCGCGCCGAGCCCTGCCT
ATGGCTCAACCCGCACAGGCAGCCCATACCCGCCGCACGGCAGGCCGTGGCCGGTGATCACATTAGTCTGGATGATACAA
AGGAGGCGGCGGCACGCTTCGCGCGCTTTGCGCCGCTGCTGGAGGGCGTGTTCCCCGAGTTGCAGGCGACGGGGGGCGTG
ATCGAGTCGCCCCTGTTACCCGCATCCAGCCTGCATGCCGCGGCGGGGCTCGTCGCGGGCCAGGGCGCGCTGTGGATCAA
GGCGGACCACCGGTTGCCCGTGGCCGGGTCCATCAAGGCACGCGGAGGCATCCATGAAGTGCTGGAGCTGGCCGAGCGCC
TGGCACTGCAGCACGGCCTGCTGACGCCGCAGTCCGATGCCGACGACTACCGCGCCCTGGCAAACCCCGCTGCGCGCGCC
GTGTTTGCGCGCTACACCGTGGCCGTGGGCTCCACGGGCAACCTGGGCCTGAGCATCGGCGTGGCGGCATCGGCGCTGGG
TTTTCACGCCGTGGTGCACATGTCGGCCGATGCCAAGGAATGGAAGAAGCAGCGTCTGCGCCAGCGCGGCGTGCAGGTGG
TGGAGCACGCGGGTGACTACGAGGGCGCTGTGGCCGCGGGGCGTGCGCAGGCGGCGCAGGACCCGTTCAGCCATTTCGTG
GACGACGAACGCTCGCTGTCGCTGCTGCTGGGTTACAGCGCCGCGGCGCTACACCTGCGCCAGCAGTTGCAGGACGCGGG
CATCGCCGTGGACGCGCAGCACCCCCTGTTCGTCTACCTGCCCTGCGGGGTGGGCGGGGCGCCGGCGGGCATCACCTTCG
GCCTGCGGCAGGTGCTGGGGGCGCATGTGCACTGCTTCTTCGCGGAGCCCGTGCAGTCGCCGTGTTTCATGGTGCAAATG
ATGGCCGGACAGGGCGCACACCCCTCGGTGTACGACTGGGGCCTCACCAACCGGACGGAAGCCGACGGCCTGGCCGTGCC
ACGCGCGTCCCTGCCCGCGGCCGAGCTGATGGAGCCGCTGCTGTCGGGCTGCTTCACCGTGTGCGACGACACCCTGTTTC
GCCAACTGGTACAGGTGCTGGATGCCACGGGCGAGCGCATCGAGCCGTCCGCAGCGGCGGGCCTGAGCGGCCCCGGTTTC
CTGACGGGCACCGAGACGGGCCGCACCTGGCTGCACGCGCAAGGTCTGTGGCCCCACCTGGCGCAGGCCACGCACCTGGT
GTGGACCACCGGCGGGCTGTACGTGCCGCCCGAGGCCTACGCGCGCTTCGAGGAACGTGGCCGGGCCCTGGGTTGA

Upstream 100 bases:

>100_bases
CATTATTCAAACTAATGCACTCGTCAATATAAATGAGTTGTATCGGTGCCGGGGCATGCCAAGAATGCCGTCTATACCCA
CCTTCCACCGACCGCAGCCC

Downstream 100 bases:

>100_bases
CGCGCCTTCGCCGAGTCCTGGCCCCGCGAAAGGATCTGTTTTTTTAACTGGCTTGACTGGAGAGAACGCCATGAACCGCA
AGACGATGTTGTCCATGCTG

Product: d-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPSVVSPQDRLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTKEAAARFARFAPLLEGVFPELQATGGV
IESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKARGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARA
VFARYTVAVGSTGNLGLSIGVAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFV
DDERSLSLLLGYSAAALHLRQQLQDAGIAVDAQHPLFVYLPCGVGGAPAGITFGLRQVLGAHVHCFFAEPVQSPCFMVQM
MAGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPLLSGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGF
LTGTETGRTWLHAQGLWPHLAQATHLVWTTGGLYVPPEAYARFEERGRALG

Sequences:

>Translated_451_residues
MPSVVSPQDRLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTKEAAARFARFAPLLEGVFPELQATGGV
IESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKARGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARA
VFARYTVAVGSTGNLGLSIGVAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFV
DDERSLSLLLGYSAAALHLRQQLQDAGIAVDAQHPLFVYLPCGVGGAPAGITFGLRQVLGAHVHCFFAEPVQSPCFMVQM
MAGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPLLSGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGF
LTGTETGRTWLHAQGLWPHLAQATHLVWTTGGLYVPPEAYARFEERGRALG
>Mature_450_residues
PSVVSPQDRLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTKEAAARFARFAPLLEGVFPELQATGGVI
ESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKARGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARAV
FARYTVAVGSTGNLGLSIGVAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFVD
DERSLSLLLGYSAAALHLRQQLQDAGIAVDAQHPLFVYLPCGVGGAPAGITFGLRQVLGAHVHCFFAEPVQSPCFMVQMM
AGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPLLSGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGFL
TGTETGRTWLHAQGLWPHLAQATHLVWTTGGLYVPPEAYARFEERGRALG

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=425, Percent_Identity=46.3529411764706, Blast_Score=337, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_ACIET (B9MIR7)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002553083.1
- GeneID:   7384696
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_1624
- ProtClustDB:   PRK02991
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 47811; Mature: 47680

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVVSPQDRLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTKEAAARF
CCCCCCHHHHHCCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
ARFAPLLEGVFPELQATGGVIESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
RGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARAVFARYTVAVGSTGNLGLSIG
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHEEEECCCCCCCEEHH
VAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFV
HHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHCCHHHHHC
DDERSLSLLLGYSAAALHLRQQLQDAGIAVDAQHPLFVYLPCGVGGAPAGITFGLRQVLG
CCCCCEEHHCCHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
AHVHCFFAEPVQSPCFMVQMMAGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPL
HHEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHH
LSGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGFLTGTETGRTWLHAQGLWPHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEECCCCHHH
AQATHLVWTTGGLYVPPEAYARFEERGRALG
HHHHEEEEECCCEECCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PSVVSPQDRLQDDAPAAQLRRAEPCLWLNPHRQPIPAARQAVAGDHISLDDTKEAAARF
CCCCCHHHHHCCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
ARFAPLLEGVFPELQATGGVIESPLLPASSLHAAAGLVAGQGALWIKADHRLPVAGSIKA
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCC
RGGIHEVLELAERLALQHGLLTPQSDADDYRALANPAARAVFARYTVAVGSTGNLGLSIG
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHEEEECCCCCCCEEHH
VAASALGFHAVVHMSADAKEWKKQRLRQRGVQVVEHAGDYEGAVAAGRAQAAQDPFSHFV
HHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHHHCCHHHHHC
DDERSLSLLLGYSAAALHLRQQLQDAGIAVDAQHPLFVYLPCGVGGAPAGITFGLRQVLG
CCCCCEEHHCCHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
AHVHCFFAEPVQSPCFMVQMMAGQGAHPSVYDWGLTNRTEADGLAVPRASLPAAELMEPL
HHEEEEECCCCCCHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHH
LSGCFTVCDDTLFRQLVQVLDATGERIEPSAAAGLSGPGFLTGTETGRTWLHAQGLWPHL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEECCCCCCEEEEECCCCHHH
AQATHLVWTTGGLYVPPEAYARFEERGRALG
HHHHEEEEECCCEECCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA