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The map label for this gene is ldcA [H]

Identifier: 222110788

GI number: 222110788

Start: 1685293

End: 1686279

Strand: Direct

Name: ldcA [H]

Synonym: Dtpsy_1593

Alternate gene names: 222110788

Gene position: 1685293-1686279 (Clockwise)

Preceding gene: 222110787

Following gene: 222110789

Centisome position: 44.39

GC content: 69.81

Gene sequence:

>987_bases
ATGCCTAACCACCCCCACGACTGCGGCCACGATCACTGCGATCACGCTCACGGCCCCCGGCACATCTACATCTACTCCCC
TTCCGGCGCGGTGCGCGACAAGGCCGCGTTCAAGCGCGGCATTGCCCGCCTGCAGGCCATGGGCCACGAGGTGGAGGTGG
ACCCGGACGCGCTCGCGTCCCACACGCGCTTTGCCGGCGACGATGCCACGCGCCTGGCCGCCATCCACCGCGCGGCCGCC
AGCGGCGCCGACGTGGCGCTGATCAGCCGCGGCGGCTACGGTCTCACGCGCATCCTGCCGGGCATCCAGTACAAGGCCGT
GGCCAAGGCGGTGGAGCGCGGAACCCAGTTCGTGGGCGTGAGCGACTTCACGGCCTTCCAGTCCGCGCTGCTGGCCAAGA
CCGGCGCCACCACCTGGGCCGGCCCGGCGCTGGTGGGAGACCTGGGCGTGCCGGGCGAGCCCGACGACATCATGCTGGCC
TGCCTGGACGATCTGCTCACCGGCCACGGCGAGGGCAGCGGCTGGCGCATGAACGCCGAGAAACCCCGCGCCGACGGCCA
GCCCGCCGTGCGCGACATCTACGTGAAGAAGGCCACCCTGTGGGGCGGCAACCTGGCCGTGCTGTGTTCGCTGGTGGGCA
CGCCGTACTTCCCGCAGGTCAAGGGCGGCGTGTTGTTCTTGGAGGACGTGGGCGAGCACCCTTACCGCGTCGAACGCCTG
CTCACCCAGCTGCTGCACGCTGGCGTGCTGGCCCAGCAAAAGGCCGTGGTGCTGGGCCAGTTCAATGAATACAAGCTCAC
GCCGCACGACAAGGGCTTCAAGCTGCAGAGCGTGGTGGACTGGCTGCGCACGCAGATCAAGGCGCCCGTGCTCACCAACC
TGCCGTTCGGCCATGTGCCCACCAAGGTGCTGCTGCCCGTGGGCGCCGAGGTGTCGCTGTCGGTCGAAGGGCGCGACGCG
CTCATCTACTGGGGCCATGCCCACTGA

Upstream 100 bases:

>100_bases
GCCTTCGCCCGTTTTGCCGATGCCGATGCCGCGCCGCTCCTCACCGTGCCGGACGCCAGCGCCGCCTCGGCGCTGCGCGC
TATGGAATACTTCACCCGCT

Downstream 100 bases:

>100_bases
GATGCTATTGATTTAAGAGCTGCCGGCGCTTTGAGGGTGGGCGCGATAGCAGGTTTTGGCTTAAAACGCCGCGACGGCGG
GGGAGGCGGCATGGGCAGAT

Product: muramoyltetrapeptide carboxypeptidase

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPNHPHDCGHDHCDHAHGPRHIYIYSPSGAVRDKAAFKRGIARLQAMGHEVEVDPDALASHTRFAGDDATRLAAIHRAAA
SGADVALISRGGYGLTRILPGIQYKAVAKAVERGTQFVGVSDFTAFQSALLAKTGATTWAGPALVGDLGVPGEPDDIMLA
CLDDLLTGHGEGSGWRMNAEKPRADGQPAVRDIYVKKATLWGGNLAVLCSLVGTPYFPQVKGGVLFLEDVGEHPYRVERL
LTQLLHAGVLAQQKAVVLGQFNEYKLTPHDKGFKLQSVVDWLRTQIKAPVLTNLPFGHVPTKVLLPVGAEVSLSVEGRDA
LIYWGHAH

Sequences:

>Translated_328_residues
MPNHPHDCGHDHCDHAHGPRHIYIYSPSGAVRDKAAFKRGIARLQAMGHEVEVDPDALASHTRFAGDDATRLAAIHRAAA
SGADVALISRGGYGLTRILPGIQYKAVAKAVERGTQFVGVSDFTAFQSALLAKTGATTWAGPALVGDLGVPGEPDDIMLA
CLDDLLTGHGEGSGWRMNAEKPRADGQPAVRDIYVKKATLWGGNLAVLCSLVGTPYFPQVKGGVLFLEDVGEHPYRVERL
LTQLLHAGVLAQQKAVVLGQFNEYKLTPHDKGFKLQSVVDWLRTQIKAPVLTNLPFGHVPTKVLLPVGAEVSLSVEGRDA
LIYWGHAH
>Mature_327_residues
PNHPHDCGHDHCDHAHGPRHIYIYSPSGAVRDKAAFKRGIARLQAMGHEVEVDPDALASHTRFAGDDATRLAAIHRAAAS
GADVALISRGGYGLTRILPGIQYKAVAKAVERGTQFVGVSDFTAFQSALLAKTGATTWAGPALVGDLGVPGEPDDIMLAC
LDDLLTGHGEGSGWRMNAEKPRADGQPAVRDIYVKKATLWGGNLAVLCSLVGTPYFPQVKGGVLFLEDVGEHPYRVERLL
TQLLHAGVLAQQKAVVLGQFNEYKLTPHDKGFKLQSVVDWLRTQIKAPVLTNLPFGHVPTKVLLPVGAEVSLSVEGRDAL
IYWGHAH

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=300, Percent_Identity=37.6666666666667, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 35225; Mature: 35093

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNHPHDCGHDHCDHAHGPRHIYIYSPSGAVRDKAAFKRGIARLQAMGHEVEVDPDALAS
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
HTRFAGDDATRLAAIHRAAASGADVALISRGGYGLTRILPGIQYKAVAKAVERGTQFVGV
HCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCCCEEECC
SDFTAFQSALLAKTGATTWAGPALVGDLGVPGEPDDIMLACLDDLLTGHGEGSGWRMNAE
HHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCC
KPRADGQPAVRDIYVKKATLWGGNLAVLCSLVGTPYFPQVKGGVLFLEDVGEHPYRVERL
CCCCCCCCHHHHEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHH
LTQLLHAGVLAQQKAVVLGQFNEYKLTPHDKGFKLQSVVDWLRTQIKAPVLTNLPFGHVP
HHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TKVLLPVGAEVSLSVEGRDALIYWGHAH
CEEEEECCCEEEEEECCCEEEEEECCCC
>Mature Secondary Structure 
PNHPHDCGHDHCDHAHGPRHIYIYSPSGAVRDKAAFKRGIARLQAMGHEVEVDPDALAS
CCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEECCHHHHHH
HTRFAGDDATRLAAIHRAAASGADVALISRGGYGLTRILPGIQYKAVAKAVERGTQFVGV
HCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCHHHHHHHHHHCCCEEECC
SDFTAFQSALLAKTGATTWAGPALVGDLGVPGEPDDIMLACLDDLLTGHGEGSGWRMNAE
HHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCC
KPRADGQPAVRDIYVKKATLWGGNLAVLCSLVGTPYFPQVKGGVLFLEDVGEHPYRVERL
CCCCCCCCHHHHEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHH
LTQLLHAGVLAQQKAVVLGQFNEYKLTPHDKGFKLQSVVDWLRTQIKAPVLTNLPFGHVP
HHHHHHHHHHHHCCEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
TKVLLPVGAEVSLSVEGRDALIYWGHAH
CEEEEECCCEEEEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]