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The map label for this gene is tadA [H]

Identifier: 222110787

GI number: 222110787

Start: 1684215

End: 1685300

Strand: Direct

Name: tadA [H]

Synonym: Dtpsy_1592

Alternate gene names: 222110787

Gene position: 1684215-1685300 (Clockwise)

Preceding gene: 222110786

Following gene: 222110788

Centisome position: 44.36

GC content: 73.85

Gene sequence:

>1086_bases
ATGAGCGAATCCGACGACGCCCACTGGATGCGCGAGGCCATCGCCCAGGCGCACGCCGCGCAGCAGGCGGGCGAGGTGCC
CGTGGGCGCCGTGCTGGTGCGCGATGGGCAGGTGATCGCCACCGGGCGCAATGCCCCCATCGCCGGGCACGACCCCACGG
CGCATGCCGAGATGGCCGCGCTGCGCGCCGGCGCGGCGCAGCTCTCCAACTACCGGCTCGACGGCTGCACGCTCTACGTC
ACGCTGGAGCCGTGCGCCATGTGCAGCGGCGCCATGCTGCACGCGCGCCTGCCGCGCGTGGTCTACGGCGCGGCGGATGC
CAAAACCGGCGCGGCGGGCTCGGTGGTCAACCTGTTCGCCGAGCCGCGTCTCAACCACCAGACCGCGGTGCAAGGTGGCG
TGCTGGCCGATGAATGCGGTGCACTGCTCAGCGACTTCTTCCGCGACCGCCGCCGCGCCCAGCGGGCGCAGCAACTGGCC
GCCCACCCGCTGCGCCAAGACGCGCTGCGCACGCCCGATGCCGCGTTCGCCCATCTGGACGGCCCCGCGCCGCATTACGT
GAGCGATCTGCCCGCGCTGGCCGGCCTGCGCCTGCACTACCTGGACGAAGGCCCACGCGACGCCGCCCGCACCTGGCTGC
TGCTGCATGCCAGTCCTGGCTGGAGCCATGGCTGGCAGCCCATGCTGGTGGCCTTCGTGCAGGCCGGCCACCGCGTGGTG
GCGCCGGACCTGATCGGCTTCGGCCGCAGCGACAAACCCAAGAAAGAAGCCGCCCACCGCCTCGACTGGCATCGACAGGT
GCTGGCCGAGCTGGTGCAGCGCCTGGCCCTGCGCGGCGTGGTGCAGGTGGCGCAGCCCGGTGCGCCGCTGCTGCCCGATG
CGGCGTCGGCGCCCCTGGTGCGCGTGCTGCATGTGCGGGGGGGCGCGCCCTGCGACGCCGCGCCGTTCCCCGATGCCGGC
CATCGCGCCGGGCCGCGCGCCTTCGCCCGTTTTGCCGATGCCGATGCCGCGCCGCTCCTCACCGTGCCGGACGCCAGCGC
CGCCTCGGCGCTGCGCGCTATGGAATACTTCACCCGCTATGCCTAA

Upstream 100 bases:

>100_bases
AGATGGACGCACTGATGCAGCAGCCACGCACCCTGCCCGAAGATTGATGGCCAAAATGGCCTCCAGCGCTTACCCATAAA
GCGCGAGCAGCTATTGAAAG

Downstream 100 bases:

>100_bases
CCACCCCCACGACTGCGGCCACGATCACTGCGATCACGCTCACGGCCCCCGGCACATCTACATCTACTCCCCTTCCGGCG
CGGTGCGCGACAAGGCCGCG

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MSESDDAHWMREAIAQAHAAQQAGEVPVGAVLVRDGQVIATGRNAPIAGHDPTAHAEMAALRAGAAQLSNYRLDGCTLYV
TLEPCAMCSGAMLHARLPRVVYGAADAKTGAAGSVVNLFAEPRLNHQTAVQGGVLADECGALLSDFFRDRRRAQRAQQLA
AHPLRQDALRTPDAAFAHLDGPAPHYVSDLPALAGLRLHYLDEGPRDAARTWLLLHASPGWSHGWQPMLVAFVQAGHRVV
APDLIGFGRSDKPKKEAAHRLDWHRQVLAELVQRLALRGVVQVAQPGAPLLPDAASAPLVRVLHVRGGAPCDAAPFPDAG
HRAGPRAFARFADADAAPLLTVPDASAASALRAMEYFTRYA

Sequences:

>Translated_361_residues
MSESDDAHWMREAIAQAHAAQQAGEVPVGAVLVRDGQVIATGRNAPIAGHDPTAHAEMAALRAGAAQLSNYRLDGCTLYV
TLEPCAMCSGAMLHARLPRVVYGAADAKTGAAGSVVNLFAEPRLNHQTAVQGGVLADECGALLSDFFRDRRRAQRAQQLA
AHPLRQDALRTPDAAFAHLDGPAPHYVSDLPALAGLRLHYLDEGPRDAARTWLLLHASPGWSHGWQPMLVAFVQAGHRVV
APDLIGFGRSDKPKKEAAHRLDWHRQVLAELVQRLALRGVVQVAQPGAPLLPDAASAPLVRVLHVRGGAPCDAAPFPDAG
HRAGPRAFARFADADAAPLLTVPDASAASALRAMEYFTRYA
>Mature_360_residues
SESDDAHWMREAIAQAHAAQQAGEVPVGAVLVRDGQVIATGRNAPIAGHDPTAHAEMAALRAGAAQLSNYRLDGCTLYVT
LEPCAMCSGAMLHARLPRVVYGAADAKTGAAGSVVNLFAEPRLNHQTAVQGGVLADECGALLSDFFRDRRRAQRAQQLAA
HPLRQDALRTPDAAFAHLDGPAPHYVSDLPALAGLRLHYLDEGPRDAARTWLLLHASPGWSHGWQPMLVAFVQAGHRVVA
PDLIGFGRSDKPKKEAAHRLDWHRQVLAELVQRLALRGVVQVAQPGAPLLPDAASAPLVRVLHVRGGAPCDAAPFPDAGH
RAGPRAFARFADADAAPLLTVPDASAASALRAMEYFTRYA

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=160, Percent_Identity=32.5, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI19923945, Length=93, Percent_Identity=46.2365591397849, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=57.4074074074074, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=42.4242424242424, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=159, Percent_Identity=34.5911949685535, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=101, Percent_Identity=40.5940594059406, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=37.1621621621622, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 38398; Mature: 38267

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESDDAHWMREAIAQAHAAQQAGEVPVGAVLVRDGQVIATGRNAPIAGHDPTAHAEMAA
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCHHHHHHH
LRAGAAQLSNYRLDGCTLYVTLEPCAMCSGAMLHARLPRVVYGAADAKTGAAGSVVNLFA
HHHHHHHHHCEEECCEEEEEEECHHHHHCCHHHHHHCCHHEEECCCCCCCCCCHHHHHHH
EPRLNHQTAVQGGVLADECGALLSDFFRDRRRAQRAQQLAAHPLRQDALRTPDAAFAHLD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECC
GPAPHYVSDLPALAGLRLHYLDEGPRDAARTWLLLHASPGWSHGWQPMLVAFVQAGHRVV
CCCCHHHHHHHHHHCCEEEECCCCCCCHHHEEEEEECCCCCCCCCHHHHHHHHHCCCEEE
APDLIGFGRSDKPKKEAAHRLDWHRQVLAELVQRLALRGVVQVAQPGAPLLPDAASAPLV
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
RVLHVRGGAPCDAAPFPDAGHRAGPRAFARFADADAAPLLTVPDASAASALRAMEYFTRY
EHEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
SESDDAHWMREAIAQAHAAQQAGEVPVGAVLVRDGQVIATGRNAPIAGHDPTAHAEMAA
CCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCCCCCCCCCHHHHHHH
LRAGAAQLSNYRLDGCTLYVTLEPCAMCSGAMLHARLPRVVYGAADAKTGAAGSVVNLFA
HHHHHHHHHCEEECCEEEEEEECHHHHHCCHHHHHHCCHHEEECCCCCCCCCCHHHHHHH
EPRLNHQTAVQGGVLADECGALLSDFFRDRRRAQRAQQLAAHPLRQDALRTPDAAFAHLD
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECC
GPAPHYVSDLPALAGLRLHYLDEGPRDAARTWLLLHASPGWSHGWQPMLVAFVQAGHRVV
CCCCHHHHHHHHHHCCEEEECCCCCCCHHHEEEEEECCCCCCCCCHHHHHHHHHCCCEEE
APDLIGFGRSDKPKKEAAHRLDWHRQVLAELVQRLALRGVVQVAQPGAPLLPDAASAPLV
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
RVLHVRGGAPCDAAPFPDAGHRAGPRAFARFADADAAPLLTVPDASAASALRAMEYFTRY
EHEECCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]