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The map label for this gene is xseA [H]

Identifier: 222110754

GI number: 222110754

Start: 1641193

End: 1642530

Strand: Direct

Name: xseA [H]

Synonym: Dtpsy_1557

Alternate gene names: 222110754

Gene position: 1641193-1642530 (Clockwise)

Preceding gene: 222110747

Following gene: 222110755

Centisome position: 43.23

GC content: 69.36

Gene sequence:

>1338_bases
GTGTTTGAGCGTGCAGATACAGGCGTGGCGCCGCGAATCTGGGAGGTTGGCGCGTTATGCCGCGCCATTGCTGATGCGCT
GGAGGCGCGGTTCAATCCTGTCGCGGTGCGCGGGGAGATCACGGGCTTCTCGCGCGCGTCCAGCGGGCACTGCTACTTCA
CGCTGAAGGATGGAAATGGTCAGATCCGCTGCGCCATGTTCCGCCGTGCGGCAGGCGTGCTGGATTTCACCCCGCGCGAC
GGCGAACTGGTCGAAGTGCGCGGCCGGCTGGGCGTGTACGAGGCACGCGGCGACCTGCAGCTCATCGTCGACAGCCTGCA
GCGCGCGGGGCAGGGGGCGCTGTTCGAGCAGTTCATGCGCCTCAAGGCGCAACTGGAGGCCGAAGGCCTGTTCGACGCGG
CGCGCAAGCGCGCGCTGCCGGCCATGCCGCGCGGCATTGGCGTGGTCACGTCGCCGGGCGCTGCGGCACTGCATGACGTG
GTGACGGCACTGCGCCGGCGCGTGCCGCACATTCCCGTGGTGTTGGTGCCGGCCCTGGTGCAGGGGGCGCAGGCGCCGGC
ATCGATTGCCGAAGCGCTATCAAAAATGTATCTGCTTGCGCAGGCAGGGCGGGCGCTGGACGGTGATTTGACTCTGAATG
CCGGGGCGTCGCCAGCCATCGACGTGATCCTGCTGGTGCGCGGCGGTGGCTCCATCGAAGACCTGTGGGCGTTCAATGAC
GAGCGCGTGGCCCGCGCCATCGTGCAGAGCCCGGTGCCGCTGGTCAGCGGTGTGGGGCATGAGACCGACTTCACCATCGC
CGACTTCTGCGCCGACCTGCGCGCGCCCACGCCCACGGCCGCCGCCGAGTTGGTGGCACAGCCGCGTGCCGTGTGGCTGG
GGGCACTCGACCTGCTGGCGCAACGGCTGGCCGACGGCGTACAGCGCCAGTTGGACCTGCGGCACCAACGGCTGGACCAG
GCGGCCCAGCGGCTGGGCCGGCCCTCGGGTTTCGTGGGGCGGCAGCAACTGCGGCTGAGCGGCCTGGAACAGCGCCTGCG
CCACGGATTGCTATTGAAAACGCAGCGGCTTACGCATGCGGGGCAAGCGCTGCAGAGTCATTTTCCTCAAATCGTGCAGC
GCAGCCTGGTGCAGCGCAGAGAGCGCCTGGAGCGCGCGGCGCTGCGGCTGCAACTGCTGGATCCGCGCCTGGTGCTGCAG
CGCGGCTATGCCTTGCTGACCGATGCGCAGGGGCAACCCGTGACGCGCCCCGCCCAGGTGCGCCTGGGCGACGCCGTGCA
TGCCCAGTTGGCCGAGGGTGAACTGGACCTGACGGTATCGCAGCGCCGCTTGCTGTGA

Upstream 100 bases:

>100_bases
ATGGGGGCGGGTTGGCGCATGGCCTTCCGCCGTGGCGCCGGATGCCCGGATCTGTGGACTAGTGCACCGGCCCGGTGCGC
GTACAAGCGTGGAGCGGCCT

Downstream 100 bases:

>100_bases
ACGCGGCGCGGGTCAATCCCGTACCAGAGGGCAGGAGTCGCCGCCCGCCTACAGCGGCGAGTGCTATTACTTTCCTACAA
TGCCCGTTGCTTCGCCGTGC

Product: exodeoxyribonuclease vii large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MFERADTGVAPRIWEVGALCRAIADALEARFNPVAVRGEITGFSRASSGHCYFTLKDGNGQIRCAMFRRAAGVLDFTPRD
GELVEVRGRLGVYEARGDLQLIVDSLQRAGQGALFEQFMRLKAQLEAEGLFDAARKRALPAMPRGIGVVTSPGAAALHDV
VTALRRRVPHIPVVLVPALVQGAQAPASIAEALSKMYLLAQAGRALDGDLTLNAGASPAIDVILLVRGGGSIEDLWAFND
ERVARAIVQSPVPLVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPRAVWLGALDLLAQRLADGVQRQLDLRHQRLDQ
AAQRLGRPSGFVGRQQLRLSGLEQRLRHGLLLKTQRLTHAGQALQSHFPQIVQRSLVQRRERLERAALRLQLLDPRLVLQ
RGYALLTDAQGQPVTRPAQVRLGDAVHAQLAEGELDLTVSQRRLL

Sequences:

>Translated_445_residues
MFERADTGVAPRIWEVGALCRAIADALEARFNPVAVRGEITGFSRASSGHCYFTLKDGNGQIRCAMFRRAAGVLDFTPRD
GELVEVRGRLGVYEARGDLQLIVDSLQRAGQGALFEQFMRLKAQLEAEGLFDAARKRALPAMPRGIGVVTSPGAAALHDV
VTALRRRVPHIPVVLVPALVQGAQAPASIAEALSKMYLLAQAGRALDGDLTLNAGASPAIDVILLVRGGGSIEDLWAFND
ERVARAIVQSPVPLVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPRAVWLGALDLLAQRLADGVQRQLDLRHQRLDQ
AAQRLGRPSGFVGRQQLRLSGLEQRLRHGLLLKTQRLTHAGQALQSHFPQIVQRSLVQRRERLERAALRLQLLDPRLVLQ
RGYALLTDAQGQPVTRPAQVRLGDAVHAQLAEGELDLTVSQRRLL
>Mature_445_residues
MFERADTGVAPRIWEVGALCRAIADALEARFNPVAVRGEITGFSRASSGHCYFTLKDGNGQIRCAMFRRAAGVLDFTPRD
GELVEVRGRLGVYEARGDLQLIVDSLQRAGQGALFEQFMRLKAQLEAEGLFDAARKRALPAMPRGIGVVTSPGAAALHDV
VTALRRRVPHIPVVLVPALVQGAQAPASIAEALSKMYLLAQAGRALDGDLTLNAGASPAIDVILLVRGGGSIEDLWAFND
ERVARAIVQSPVPLVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPRAVWLGALDLLAQRLADGVQRQLDLRHQRLDQ
AAQRLGRPSGFVGRQQLRLSGLEQRLRHGLLLKTQRLTHAGQALQSHFPQIVQRSLVQRRERLERAALRLQLLDPRLVLQ
RGYALLTDAQGQPVTRPAQVRLGDAVHAQLAEGELDLTVSQRRLL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=456, Percent_Identity=38.3771929824561, Blast_Score=295, Evalue=5e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 48336; Mature: 48336

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERADTGVAPRIWEVGALCRAIADALEARFNPVAVRGEITGFSRASSGHCYFTLKDGNG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEECCCC
QIRCAMFRRAAGVLDFTPRDGELVEVRGRLGVYEARGDLQLIVDSLQRAGQGALFEQFMR
CEEEHHHHHHCCCEEECCCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHH
LKAQLEAEGLFDAARKRALPAMPRGIGVVTSPGAAALHDVVTALRRRVPHIPVVLVPALV
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QGAQAPASIAEALSKMYLLAQAGRALDGDLTLNAGASPAIDVILLVRGGGSIEDLWAFND
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCHHHHHCCCH
ERVARAIVQSPVPLVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPRAVWLGALDLLA
HHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
QRLADGVQRQLDLRHQRLDQAAQRLGRPSGFVGRQQLRLSGLEQRLRHGLLLKTQRLTHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GQALQSHFPQIVQRSLVQRRERLERAALRLQLLDPRLVLQRGYALLTDAQGQPVTRPAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCCCCHHE
RLGDAVHAQLAEGELDLTVSQRRLL
ECCHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure
MFERADTGVAPRIWEVGALCRAIADALEARFNPVAVRGEITGFSRASSGHCYFTLKDGNG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEEECCCC
QIRCAMFRRAAGVLDFTPRDGELVEVRGRLGVYEARGDLQLIVDSLQRAGQGALFEQFMR
CEEEHHHHHHCCCEEECCCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCHHHHHHHH
LKAQLEAEGLFDAARKRALPAMPRGIGVVTSPGAAALHDVVTALRRRVPHIPVVLVPALV
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
QGAQAPASIAEALSKMYLLAQAGRALDGDLTLNAGASPAIDVILLVRGGGSIEDLWAFND
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEEECCCCHHHHHCCCH
ERVARAIVQSPVPLVSGVGHETDFTIADFCADLRAPTPTAAAELVAQPRAVWLGALDLLA
HHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
QRLADGVQRQLDLRHQRLDQAAQRLGRPSGFVGRQQLRLSGLEQRLRHGLLLKTQRLTHA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHH
GQALQSHFPQIVQRSLVQRRERLERAALRLQLLDPRLVLQRGYALLTDAQGQPVTRPAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCCCCCCHHE
RLGDAVHAQLAEGELDLTVSQRRLL
ECCHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA