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The map label for this gene is cysW [H]

Identifier: 222110718

GI number: 222110718

Start: 1603194

End: 1604105

Strand: Direct

Name: cysW [H]

Synonym: Dtpsy_1521

Alternate gene names: 222110718

Gene position: 1603194-1604105 (Clockwise)

Preceding gene: 222110717

Following gene: 222110719

Centisome position: 42.23

GC content: 67.0

Gene sequence:

>912_bases
ATGAGCGCCGCGAACACCCGTACCGTGCGGCGCGCGCAGGCCGGAACGACCGAGGCGCGCTGGATCCAGTGGGCGCTGAT
TGGCCTTGCCATGGTGTTCCTGCTGCTGTTCCTGGTGTTGCCGCTGGCCGCCGTGTTCACCGAGGCGCTGCGCAAGGGCG
TGAATGCCTACCTGGAGGGATTGCGCGAGCCCGACGCCTGGTCTGCCATCCAGCTCACGCTGCTCACTGCCGTGATCGCC
GTGCCGCTGAACCTGGTGTTCGGCATCGCCGCGGCGTGGTGCATCGCCAAGTACGAGTTCAAGGGCAAGGCCTTCTTGAC
CACGCTGATCGATCTGCCGTTCTCCATCTCGCCCGTAGTGGCGGGCCTGATGTACGTGCTGGTGTTCGGCGCCAACGGCT
GGCTGGGGCCCTGGCTGGCGGCGCACGACATCAAGATCATCTTCGCCGTGCCGGGCATCGTGCTGGCCACCGTGTTCGTC
ACGTTCCCGTTCATCGCGCGTGAACTGATCCCGCTGATGCAGGCGCAAGGCAACGACGAGGAGCAGGCGGCGGTGGTGCT
GGGCGCGAGCGGCTGGCAGACCTTCTGGCACGTGACGCTGCCCAACATCAAGTGGGGCCTGCTGTACGGCGTGATCCTGT
GCAATGCCCGGGCGATGGGCGAGTTTGGCGCGGTGTCGGTGGTGTCGGGCCACATCCGCGGCCAGACCAACACCATCCCG
CTGCACGTGGAGATCCTCTACAACGAATACCAATCGGTGGCCGCGTTCGCAGCCGCCTCGCTGCTGGCACTGCTGGCATT
GGTCACGCTGGTCATCAAGTCGGTGGCCGAGTGGAAGAGCGAACAGGAAATGAAGGCTGCTGCCGCGCTGCCGCCCGAGC
GGCCTGCGCCCGCGCCCGGCGCGCCGCGCTGA

Upstream 100 bases:

>100_bases
CCACTGCCGTGGCGGTGGTGATGCTGGTGATCTCTTTCGTCCTTCTGCTGGTCATCAACGCCTTGCAGGCCTGGCAGCGC
CGCCACGCAGGAGCACCCGC

Downstream 100 bases:

>100_bases
AGGATGAACACATGAGCATTGAAATCCGCAACGTCAGCAAGCAGTTCGGCGACTTCCAGGCGCTGCGCGACGTCAGCCTG
GACATCCAGTCGGGCGAACT

Product: sulfate ABC transporter inner membrane subunit cysw

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSAANTRTVRRAQAGTTEARWIQWALIGLAMVFLLLFLVLPLAAVFTEALRKGVNAYLEGLREPDAWSAIQLTLLTAVIA
VPLNLVFGIAAAWCIAKYEFKGKAFLTTLIDLPFSISPVVAGLMYVLVFGANGWLGPWLAAHDIKIIFAVPGIVLATVFV
TFPFIARELIPLMQAQGNDEEQAAVVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKSVAEWKSEQEMKAAAALPPERPAPAPGAPR

Sequences:

>Translated_303_residues
MSAANTRTVRRAQAGTTEARWIQWALIGLAMVFLLLFLVLPLAAVFTEALRKGVNAYLEGLREPDAWSAIQLTLLTAVIA
VPLNLVFGIAAAWCIAKYEFKGKAFLTTLIDLPFSISPVVAGLMYVLVFGANGWLGPWLAAHDIKIIFAVPGIVLATVFV
TFPFIARELIPLMQAQGNDEEQAAVVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKSVAEWKSEQEMKAAAALPPERPAPAPGAPR
>Mature_302_residues
SAANTRTVRRAQAGTTEARWIQWALIGLAMVFLLLFLVLPLAAVFTEALRKGVNAYLEGLREPDAWSAIQLTLLTAVIAV
PLNLVFGIAAAWCIAKYEFKGKAFLTTLIDLPFSISPVVAGLMYVLVFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVT
FPFIARELIPLMQAQGNDEEQAAVVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIPL
HVEILYNEYQSVAAFAAASLLALLALVTLVIKSVAEWKSEQEMKAAAALPPERPAPAPGAPR

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=279, Percent_Identity=51.6129032258064, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=38.8349514563107, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786980, Length=223, Percent_Identity=34.0807174887892, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32659; Mature: 32528

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAANTRTVRRAQAGTTEARWIQWALIGLAMVFLLLFLVLPLAAVFTEALRKGVNAYLEG
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREPDAWSAIQLTLLTAVIAVPLNLVFGIAAAWCIAKYEFKGKAFLTTLIDLPFSISPVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
AGLMYVLVFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVTFPFIARELIPLMQAQGNDE
HHHHHHHHHCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EQAAVVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
CCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCCCEEE
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKSVAEWKSEQEMKAAAALPPERPAPAPG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
APR
CCC
>Mature Secondary Structure 
SAANTRTVRRAQAGTTEARWIQWALIGLAMVFLLLFLVLPLAAVFTEALRKGVNAYLEG
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREPDAWSAIQLTLLTAVIAVPLNLVFGIAAAWCIAKYEFKGKAFLTTLIDLPFSISPVV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHH
AGLMYVLVFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVTFPFIARELIPLMQAQGNDE
HHHHHHHHHCCCCCCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EQAAVVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
CCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCCCEEE
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKSVAEWKSEQEMKAAAALPPERPAPAPG
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
APR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]