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The map label for this gene is infC [H]

Identifier: 222110647

GI number: 222110647

Start: 1517487

End: 1518023

Strand: Direct

Name: infC [H]

Synonym: Dtpsy_1449

Alternate gene names: 222110647

Gene position: 1517487-1518023 (Clockwise)

Preceding gene: 222110646

Following gene: 222110648

Centisome position: 39.97

GC content: 60.34

Gene sequence:

>537_bases
ATGGCGCCTGAAGTGCGCCTGTCCGGTCCGGACAACGAGCCCCTGGGCATCGTCAGCCTGCAAGAGGCCCTGCGCATGGC
GGGCGAGCTGGATGTGGACTTGGTTGAAATTGCAGCCACGGCTAATCCACCGGTCTGCCGCCTGATGGACTACGGCAAGT
TCAAGTATCAGGAGCAGAAGAAGGCGGCCGAGGCCAAGGCCAAGCAAACGGTCATCGAGATCAAAGAAGTCAAGTTCCGC
CCTGGTACGGACGATGGTGACTACAACATCAAGCTGCGCAACATCCGCCGTTTTCTGGCGGAGGGCGATAAGTGCAAGAT
CACGCTGCGCTTCCGTGGCCGCGAGATCACGCACCAGGAGTTGGGCCTGGCATTGCTCAACCGCTTGAGGGATGACCTGG
GCGACACCATTTTGGTGGAGCAGTTTCCCAAGCTGGAAGGTCGCCAAATGATCATGATGATCGCGCCGGCCCGCAAGAAG
CCGGCAGGTAAACCTGCCGCCGAAAGCGCTCCCGCCGCTGACGACAACGCTGCGTAA

Upstream 100 bases:

>100_bases
GCTTTTCGTAGCTTTTTAATTGAAGGTGAGAGCCATCGCTACCGAATTTCGTGACCGTCGCCAGCGCGAGGAGCGCAAGC
ATCGACTGAACCGTGAAATC

Downstream 100 bases:

>100_bases
GCAAGGAGATTTGGCGGGCGCCCCCTAAAAAAGGGTGCCGGCCGATAGGCGGCATGCAAGTGCCGCCGCACGGCGAGCCG
CAAGGCGCGTCGTTTGAAAA

Product: translation initiation factor if-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MAPEVRLSGPDNEPLGIVSLQEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKKAAEAKAKQTVIEIKEVKFR
PGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQELGLALLNRLRDDLGDTILVEQFPKLEGRQMIMMIAPARKK
PAGKPAAESAPAADDNAA

Sequences:

>Translated_178_residues
MAPEVRLSGPDNEPLGIVSLQEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKKAAEAKAKQTVIEIKEVKFR
PGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQELGLALLNRLRDDLGDTILVEQFPKLEGRQMIMMIAPARKK
PAGKPAAESAPAADDNAA
>Mature_177_residues
APEVRLSGPDNEPLGIVSLQEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQKKAAEAKAKQTVIEIKEVKFRP
GTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQELGLALLNRLRDDLGDTILVEQFPKLEGRQMIMMIAPARKKP
AGKPAAESAPAADDNAA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=160, Percent_Identity=62.5, Blast_Score=197, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19757; Mature: 19626

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPEVRLSGPDNEPLGIVSLQEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQK
CCCCEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
KAAEAKAKQTVIEIKEVKFRPGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHH
LGLALLNRLRDDLGDTILVEQFPKLEGRQMIMMIAPARKKPAGKPAAESAPAADDNAA
HHHHHHHHHHHHHCCEEEEHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
APEVRLSGPDNEPLGIVSLQEALRMAGELDVDLVEIAATANPPVCRLMDYGKFKYQEQK
CCCEECCCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHH
KAAEAKAKQTVIEIKEVKFRPGTDDGDYNIKLRNIRRFLAEGDKCKITLRFRGREITHQE
HHHHHHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHH
LGLALLNRLRDDLGDTILVEQFPKLEGRQMIMMIAPARKKPAGKPAAESAPAADDNAA
HHHHHHHHHHHHHCCEEEEHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]