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The map label for this gene is 222110533

Identifier: 222110533

GI number: 222110533

Start: 1391462

End: 1393717

Strand: Direct

Name: 222110533

Synonym: Dtpsy_1332

Alternate gene names: NA

Gene position: 1391462-1393717 (Clockwise)

Preceding gene: 222110532

Following gene: 222110534

Centisome position: 36.65

GC content: 59.0

Gene sequence:

>2256_bases
ATGGGACGACAGCTGCAGCTCAATTTCACGCCGCTGTATGTGCGCGGCGATGCCGTTCGGCTGCAGACCTTGCCCTTCAA
GGACGCGCAGCAGTTCCGGAACCTGCGTGATGAGTACCGCACGCATTACGCCGTAACCCGTCGCGCGGATCAGATCGTGG
CGTTACCTCTCGCATTGGGCACCGCGCCCATTGGCGAAGAGAAGGTTGTGTCGGTGGTTGAGTATGCGTCCCTCATTCGT
CCTCTGCTTGAGCAGCGTCTCGTGACGTTGCTCAGTTCCAATCGGCGACTGGTAGCGCGCTATAACCCGATTACCACCGT
AGGGCGGACCTTGCCGACGGGCTTCAGCGAAGCCGACAAGCATCTTCATCTGCAGTCGCGCGTCTTGATCGCCATTCGAT
CGTTAAAGCTGCCGGACTCAGAACCACTCGGTCTTTTGTGGGACATCGAGATCCAGAAGACTTGCGCAACGAGCCTTGCC
GTATTGCATGAGCACGGAGTTCGACTTGATGGTTTGACGGTTGAGCGCATGGTACCGGTTGAGGATGCGCGCATGCTGCC
TTATCGCAGGCTGGTGGGCCGAGTCGGGGCCATCGCAGACGGTAACGCTCGCATGTCGGAGCGCTTTCAAAATGTGGATG
AGTCGCTTCCACTCGACGAACTGTATCTGGAGGCGTCGCCAGAGAATCTTCGGCACCTTCTGCAGCACTTCACGCGGAAC
GCATCGGGCAGGGTGCTTGGCAAGATCGATGAGATCGTGTTTGAGAACAGCCGAGGGCGTGCTCGCATGGAGCACATTGC
ACGCATTTCGGACTGGCTACGCGGTCTCGGTGAAATCGAACTGCAGGAAGGTCTCAGCGTCGGCATTGGCAACCTGCTGA
GCGAGAAGGACGCGCCGAACTTTCCCCGTTTCACGGAAGCCACGACGCCGACCTATGTTTTCGACGCCGGCACGCTCAAG
TCGGAGTCGCGTGCAGCGGTCGGGCTAAGCAAGTTTGGCCCCTACAGCAGGCACGTGTTCACGCCCACTCGACCGAACGT
CTGCGTGATCTGCGATCGCGCGCGGCGTGGTCAATTTGAACTGTTCCTTCGAAAGTTTCGAGACGGCTTGTCGGTCGACG
GCAAGTCATTGCCGTTCGGGCGAGGATTTCTCGGCATTTACGGACTGCAGGACATCACACTGACGTTCGTGGAGGCGGAC
GCGTTCACGGCCGACGCATACCATGCCGCTGCTTCCAAAGCAGTCCGGATGGCTGCCGAGGGCGCGCCCTGGCATCTTGC
CCTGGTGCAGACCGAGCGGGACTCGCGCCAGTTGGCGCCCCAGAAGAATCCGTACCTGGTGGCCAAGGCGGCGTTTCTCT
CCAATCAGATCCCCACGCAGTTCATCGCGTTCGAGACGTTCTCGATGGCCCCGGCCAGTCTTGCCTACACCCTGAGCAAC
CTCGCGCTTGCTGTCTATGCCAAGCTCGGCGGCATCCCATGGCTGATCAAATCGGACAAGGGCATCGCACATGAAGTAGT
CATCGGGCTCGGCAGCGCCGCTATCGGCGAGTCCCGATTTTCCAGAAAAGAGAGAATCGTCGGCATTACTAGCGTCTTTC
GCGGCGACGGCGGCTATCTGCTATCGAATCTGTCGAACGCCGTGCCCATGTCGAAGTACGGTGAGGCACTGACGGAATCA
CTGCAGGGAACCCTTCAGCGTGTGCGAAGTGAAATGAACTGGATCAAGGGCGATTCTGTCCGCGTGATCGTTCATGCGTT
CAAGCCGATGCGCAATACGGAGGTCGAGTCGGTTAAAGCGGCGTTGAAGGAGTTCTCTGAATTCGATCTGCGGTTCGCCT
TCTTGCATGTAAAGCAGGACCATCCGTATCTGCTGTTCGACGACGATTCCATCGGGACCAAGGGCAGGGGAGAGAAAACG
CCGATCCGGGGCCTCTTTGCGGAAGTCGGCCACAACGAGACGTTGTTGACGTTGACGGGGCCGCAGCAGCTCAAGCGCCC
GACGGATGGCTTGCCCAAACCGCTACTGCTGAGTCTTCATCGTGATTCGACGTTCACGGACATCATCTATCTGACCAAGC
AGGTCTACTGGTTTTCGAACCATTCCTGGCGCAGCTTCCTGCCAGCGGCGATGCCCGTCACCATCTATTACTCCGACCTT
GTCGCGGGCCTCCTAGGGCGGCTTGACCGGTTGGGTAGCCGGTGGAGTCCCAGTGTGATGCTGGGCAAGATTGGCACAAC
ACGGTGGTTTCTGTGA

Upstream 100 bases:

>100_bases
CGGGAAACCATCCCAGCTGGCGCGTTGGACCCGGTTCATCGGTGCATCAACCAAAAAATTGCGGACGCGGGTCTGGCAAA
ACAAGAGGATGTGACGACCT

Downstream 100 bases:

>100_bases
GCGCCGGCAACCCGATGCTGCACGAGGCGCTGCGAGCCGTAGCAGCTCAGGCCGAGACGCTGACGAGTGCGGGCCCGGTG
TCGATCGCCTTTTATCACTG

Product: stem cell self-renewal protein piwi domain-containing protein

Products: NA

Alternate protein names: AfPiwi [H]

Number of amino acids: Translated: 751; Mature: 750

Protein sequence:

>751_residues
MGRQLQLNFTPLYVRGDAVRLQTLPFKDAQQFRNLRDEYRTHYAVTRRADQIVALPLALGTAPIGEEKVVSVVEYASLIR
PLLEQRLVTLLSSNRRLVARYNPITTVGRTLPTGFSEADKHLHLQSRVLIAIRSLKLPDSEPLGLLWDIEIQKTCATSLA
VLHEHGVRLDGLTVERMVPVEDARMLPYRRLVGRVGAIADGNARMSERFQNVDESLPLDELYLEASPENLRHLLQHFTRN
ASGRVLGKIDEIVFENSRGRARMEHIARISDWLRGLGEIELQEGLSVGIGNLLSEKDAPNFPRFTEATTPTYVFDAGTLK
SESRAAVGLSKFGPYSRHVFTPTRPNVCVICDRARRGQFELFLRKFRDGLSVDGKSLPFGRGFLGIYGLQDITLTFVEAD
AFTADAYHAAASKAVRMAAEGAPWHLALVQTERDSRQLAPQKNPYLVAKAAFLSNQIPTQFIAFETFSMAPASLAYTLSN
LALAVYAKLGGIPWLIKSDKGIAHEVVIGLGSAAIGESRFSRKERIVGITSVFRGDGGYLLSNLSNAVPMSKYGEALTES
LQGTLQRVRSEMNWIKGDSVRVIVHAFKPMRNTEVESVKAALKEFSEFDLRFAFLHVKQDHPYLLFDDDSIGTKGRGEKT
PIRGLFAEVGHNETLLTLTGPQQLKRPTDGLPKPLLLSLHRDSTFTDIIYLTKQVYWFSNHSWRSFLPAAMPVTIYYSDL
VAGLLGRLDRLGSRWSPSVMLGKIGTTRWFL

Sequences:

>Translated_751_residues
MGRQLQLNFTPLYVRGDAVRLQTLPFKDAQQFRNLRDEYRTHYAVTRRADQIVALPLALGTAPIGEEKVVSVVEYASLIR
PLLEQRLVTLLSSNRRLVARYNPITTVGRTLPTGFSEADKHLHLQSRVLIAIRSLKLPDSEPLGLLWDIEIQKTCATSLA
VLHEHGVRLDGLTVERMVPVEDARMLPYRRLVGRVGAIADGNARMSERFQNVDESLPLDELYLEASPENLRHLLQHFTRN
ASGRVLGKIDEIVFENSRGRARMEHIARISDWLRGLGEIELQEGLSVGIGNLLSEKDAPNFPRFTEATTPTYVFDAGTLK
SESRAAVGLSKFGPYSRHVFTPTRPNVCVICDRARRGQFELFLRKFRDGLSVDGKSLPFGRGFLGIYGLQDITLTFVEAD
AFTADAYHAAASKAVRMAAEGAPWHLALVQTERDSRQLAPQKNPYLVAKAAFLSNQIPTQFIAFETFSMAPASLAYTLSN
LALAVYAKLGGIPWLIKSDKGIAHEVVIGLGSAAIGESRFSRKERIVGITSVFRGDGGYLLSNLSNAVPMSKYGEALTES
LQGTLQRVRSEMNWIKGDSVRVIVHAFKPMRNTEVESVKAALKEFSEFDLRFAFLHVKQDHPYLLFDDDSIGTKGRGEKT
PIRGLFAEVGHNETLLTLTGPQQLKRPTDGLPKPLLLSLHRDSTFTDIIYLTKQVYWFSNHSWRSFLPAAMPVTIYYSDL
VAGLLGRLDRLGSRWSPSVMLGKIGTTRWFL
>Mature_750_residues
GRQLQLNFTPLYVRGDAVRLQTLPFKDAQQFRNLRDEYRTHYAVTRRADQIVALPLALGTAPIGEEKVVSVVEYASLIRP
LLEQRLVTLLSSNRRLVARYNPITTVGRTLPTGFSEADKHLHLQSRVLIAIRSLKLPDSEPLGLLWDIEIQKTCATSLAV
LHEHGVRLDGLTVERMVPVEDARMLPYRRLVGRVGAIADGNARMSERFQNVDESLPLDELYLEASPENLRHLLQHFTRNA
SGRVLGKIDEIVFENSRGRARMEHIARISDWLRGLGEIELQEGLSVGIGNLLSEKDAPNFPRFTEATTPTYVFDAGTLKS
ESRAAVGLSKFGPYSRHVFTPTRPNVCVICDRARRGQFELFLRKFRDGLSVDGKSLPFGRGFLGIYGLQDITLTFVEADA
FTADAYHAAASKAVRMAAEGAPWHLALVQTERDSRQLAPQKNPYLVAKAAFLSNQIPTQFIAFETFSMAPASLAYTLSNL
ALAVYAKLGGIPWLIKSDKGIAHEVVIGLGSAAIGESRFSRKERIVGITSVFRGDGGYLLSNLSNAVPMSKYGEALTESL
QGTLQRVRSEMNWIKGDSVRVIVHAFKPMRNTEVESVKAALKEFSEFDLRFAFLHVKQDHPYLLFDDDSIGTKGRGEKTP
IRGLFAEVGHNETLLTLTGPQQLKRPTDGLPKPLLLSLHRDSTFTDIIYLTKQVYWFSNHSWRSFLPAAMPVTIYYSDLV
AGLLGRLDRLGSRWSPSVMLGKIGTTRWFL

Specific function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as short interfering RNAs (siRNAs), and may cleave or repress the translation of mRNAs which are complementary to them [H]

COG id: COG1431

COG function: function code J; Uncharacterized protein containing piwi/argonaute domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Piwi domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003165
- InterPro:   IPR012337 [H]

Pfam domain/function: PF02171 Piwi [H]

EC number: NA

Molecular weight: Translated: 83875; Mature: 83743

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50822 PIWI

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRQLQLNFTPLYVRGDAVRLQTLPFKDAQQFRNLRDEYRTHYAVTRRADQIVALPLALG
CCCEEEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHC
TAPIGEEKVVSVVEYASLIRPLLEQRLVTLLSSNRRLVARYNPITTVGRTLPTGFSEADK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCHHHHH
HLHLQSRVLIAIRSLKLPDSEPLGLLWDIEIQKTCATSLAVLHEHGVRLDGLTVERMVPV
HHHHHHHHEEHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCEECCEEHEEECCC
EDARMLPYRRLVGRVGAIADGNARMSERFQNVDESLPLDELYLEASPENLRHLLQHFTRN
CHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCHHHCCCHHHEEEECCHHHHHHHHHHHHCC
ASGRVLGKIDEIVFENSRGRARMEHIARISDWLRGLGEIELQEGLSVGIGNLLSEKDAPN
CCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEHHCCCHHHHHHHHCCCCCCC
FPRFTEATTPTYVFDAGTLKSESRAAVGLSKFGPYSRHVFTPTRPNVCVICDRARRGQFE
CCCCCCCCCCEEEEECCCCCCCCHHHCCHHHCCCCCCEEECCCCCCEEEEECCCCCCHHH
LFLRKFRDGLSVDGKSLPFGRGFLGIYGLQDITLTFVEADAFTADAYHAAASKAVRMAAE
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GAPWHLALVQTERDSRQLAPQKNPYLVAKAAFLSNQIPTQFIAFETFSMAPASLAYTLSN
CCCEEEEEEEECCCHHHCCCCCCCEEEEEHHHHCCCCCCCEEEEEHHCCCHHHHHHHHHH
LALAVYAKLGGIPWLIKSDKGIAHEVVIGLGSAAIGESRFSRKERIVGITSVFRGDGGYL
HHHHHHHHHCCCCEEEECCCCCHHHHHEECCCHHHCHHHHHHHHHEEEEHHHHCCCCCHH
LSNLSNAVPMSKYGEALTESLQGTLQRVRSEMNWIKGDSVRVIVHAFKPMRNTEVESVKA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH
ALKEFSEFDLRFAFLHVKQDHPYLLFDDDSIGTKGRGEKTPIRGLFAEVGHNETLLTLTG
HHHHHHHHCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
PQQLKRPTDGLPKPLLLSLHRDSTFTDIIYLTKQVYWFSNHSWRSFLPAAMPVTIYYSDL
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHCCCCCCCEEEHHHH
VAGLLGRLDRLGSRWSPSVMLGKIGTTRWFL
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
GRQLQLNFTPLYVRGDAVRLQTLPFKDAQQFRNLRDEYRTHYAVTRRADQIVALPLALG
CCEEEEEEEEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHC
TAPIGEEKVVSVVEYASLIRPLLEQRLVTLLSSNRRLVARYNPITTVGRTLPTGFSEADK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCHHHHH
HLHLQSRVLIAIRSLKLPDSEPLGLLWDIEIQKTCATSLAVLHEHGVRLDGLTVERMVPV
HHHHHHHHEEHHHHCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHCCCEECCEEHEEECCC
EDARMLPYRRLVGRVGAIADGNARMSERFQNVDESLPLDELYLEASPENLRHLLQHFTRN
CHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCHHHCCCHHHEEEECCHHHHHHHHHHHHCC
ASGRVLGKIDEIVFENSRGRARMEHIARISDWLRGLGEIELQEGLSVGIGNLLSEKDAPN
CCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCCEEHHCCCHHHHHHHHCCCCCCC
FPRFTEATTPTYVFDAGTLKSESRAAVGLSKFGPYSRHVFTPTRPNVCVICDRARRGQFE
CCCCCCCCCCEEEEECCCCCCCCHHHCCHHHCCCCCCEEECCCCCCEEEEECCCCCCHHH
LFLRKFRDGLSVDGKSLPFGRGFLGIYGLQDITLTFVEADAFTADAYHAAASKAVRMAAE
HHHHHHHCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCC
GAPWHLALVQTERDSRQLAPQKNPYLVAKAAFLSNQIPTQFIAFETFSMAPASLAYTLSN
CCCEEEEEEEECCCHHHCCCCCCCEEEEEHHHHCCCCCCCEEEEEHHCCCHHHHHHHHHH
LALAVYAKLGGIPWLIKSDKGIAHEVVIGLGSAAIGESRFSRKERIVGITSVFRGDGGYL
HHHHHHHHHCCCCEEEECCCCCHHHHHEECCCHHHCHHHHHHHHHEEEEHHHHCCCCCHH
LSNLSNAVPMSKYGEALTESLQGTLQRVRSEMNWIKGDSVRVIVHAFKPMRNTEVESVKA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHH
ALKEFSEFDLRFAFLHVKQDHPYLLFDDDSIGTKGRGEKTPIRGLFAEVGHNETLLTLTG
HHHHHHHHCEEEEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECC
PQQLKRPTDGLPKPLLLSLHRDSTFTDIIYLTKQVYWFSNHSWRSFLPAAMPVTIYYSDL
HHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHEEEECCCCHHHHCCCCCCCEEEHHHH
VAGLLGRLDRLGSRWSPSVMLGKIGTTRWFL
HHHHHHHHHHCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]