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The map label for this gene is yaeL [C]

Identifier: 222110433

GI number: 222110433

Start: 1291782

End: 1293146

Strand: Direct

Name: yaeL [C]

Synonym: Dtpsy_1230

Alternate gene names: 222110433

Gene position: 1291782-1293146 (Clockwise)

Preceding gene: 222110432

Following gene: 222110434

Centisome position: 34.02

GC content: 67.91

Gene sequence:

>1365_bases
ATGCTGCTGACTGTCGTTGCCTTCATCGTTGCGTTGGGCGTGCTGATCGCCGTGCACGAGTACGGCCATTACCGCGTGGC
GGTGGCCTGCGGTGTCAAGGTCCTCCGCTTCTCGGTCGGCTTTGGCAAGCCTTTGCTGCGTTGGCAGCCTAAGGGCTCAC
CCACGGAATTCGTCATCGGCGCCTTTCCGCTGGGAGGGTACGTGCGCATGCTGGACGAGCGTGAGGCGCCCGTTGAGCCG
CATGAACGCCACCTGGCCTTCAATACCCAGCCCCTGCGTTCGCGCGCCGCCATCGTTGCCGCGGGGCCGCTGGCCAATCT
ACTGCTGGCGGTGCTGTTGTATGCCGCCGTCAACTGGAGCGGCGTGGACGAGCCCAAGGCCTACCTGGCCAGCCCTGTAG
CGGGGTCGGTGGCCGAGCAGGCGGGCCTGCGCGGCGGCGAACTGGTGGTGTCCGCCGGGCTGGGCGAGGGCGATTTCGAG
CCCGTGCGCTCGTTCGAAGACCTGCGTTGGACGCTCACGCGCGGCGCGCTGGACGGGCAGAACGTGCGGCTGCTGCTGCA
GCCTGAGCGCGGCTCGACGCCGCGCGAGGTGCTGTTGCGCATAGATCAGCTGGACGTGCGCGAGGCCGATGTGCAGCTGT
ATCGCCGCATCGGCATCACCGCGCCCTGGACGCGACCCGTGCTGGGCGAGGTCGTGCCAGGCGGCGCGGCTGCGCGTGCG
GGGCTGCGCGCTGGTGATGTGGTTCTGCGCCTGGGCAGTGCGGCGGTGGTGGACGGCGTGCAACTGCGCGAGCTGATACG
CGCGTCCGTGCAGGCGGGCCAGCCGCTCACGCAGGTCTGGCGCATCGAGCGCGACGGTCAGCCGCGCGACCTGGAAGTCA
CGCCCGAAGTGGCACAGGAGGCGGGCGGCGCCGTGGGACGCGTCGGCGCCTATGTGGGCGCGCCGCCCGAGATGGTGAAC
GTGCATTACGGCCCCTTGGAAGGGCTCTGGAAAGGCACGGTGCGCACATGGGAGGTGTCGGTCCTCACGCTGCGCATGAT
GGGCCGCATGGTGATCGGTGAGGCTTCGCTCAAGAACCTCAGCGGGCCGCTGACCATCGCCGATTACGCAGGCCGTTCCG
CCAGCATGGGGCTGACCCAGTACCTCAGCTTCCTCGCACTCATCAGCGTGAGCCTGGGAGTGCTGAACCTGCTTCCGCTG
CCCGTATTGGATGGTGGGCACCTGATGTATTATCTTTGGGAGGGGGTGACGGGACGGGGCGTGTCCGAAGCCTGGATGGA
GCGGCTGCAGCGCACAGGCGTCGCGGTGCTTCTCCTCATGATGTCCATCGCCCTGTTCAACGACCTCACCCGGCTTTTTG
GCTAA

Upstream 100 bases:

>100_bases
AGCGTCTTGCGCTTGTCACATAAGGGTTACAGGTGCGTTTTATATTCAAACCATTGCTGGATAAGCGCAAGGCGCTCTGA
TTTTTGTAGGAACCCTAGGC

Downstream 100 bases:

>100_bases
CCTTTTCGCCGCCGTTGCGCTGCACTGTCGGCTCCAGCTTCATCCATGAGAAAACATATCAATCGCCTGGGCGTGCGTAC
GGCATCCGCCCTCGCAGCCA

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MLLTVVAFIVALGVLIAVHEYGHYRVAVACGVKVLRFSVGFGKPLLRWQPKGSPTEFVIGAFPLGGYVRMLDEREAPVEP
HERHLAFNTQPLRSRAAIVAAGPLANLLLAVLLYAAVNWSGVDEPKAYLASPVAGSVAEQAGLRGGELVVSAGLGEGDFE
PVRSFEDLRWTLTRGALDGQNVRLLLQPERGSTPREVLLRIDQLDVREADVQLYRRIGITAPWTRPVLGEVVPGGAAARA
GLRAGDVVLRLGSAAVVDGVQLRELIRASVQAGQPLTQVWRIERDGQPRDLEVTPEVAQEAGGAVGRVGAYVGAPPEMVN
VHYGPLEGLWKGTVRTWEVSVLTLRMMGRMVIGEASLKNLSGPLTIADYAGRSASMGLTQYLSFLALISVSLGVLNLLPL
PVLDGGHLMYYLWEGVTGRGVSEAWMERLQRTGVAVLLLMMSIALFNDLTRLFG

Sequences:

>Translated_454_residues
MLLTVVAFIVALGVLIAVHEYGHYRVAVACGVKVLRFSVGFGKPLLRWQPKGSPTEFVIGAFPLGGYVRMLDEREAPVEP
HERHLAFNTQPLRSRAAIVAAGPLANLLLAVLLYAAVNWSGVDEPKAYLASPVAGSVAEQAGLRGGELVVSAGLGEGDFE
PVRSFEDLRWTLTRGALDGQNVRLLLQPERGSTPREVLLRIDQLDVREADVQLYRRIGITAPWTRPVLGEVVPGGAAARA
GLRAGDVVLRLGSAAVVDGVQLRELIRASVQAGQPLTQVWRIERDGQPRDLEVTPEVAQEAGGAVGRVGAYVGAPPEMVN
VHYGPLEGLWKGTVRTWEVSVLTLRMMGRMVIGEASLKNLSGPLTIADYAGRSASMGLTQYLSFLALISVSLGVLNLLPL
PVLDGGHLMYYLWEGVTGRGVSEAWMERLQRTGVAVLLLMMSIALFNDLTRLFG
>Mature_454_residues
MLLTVVAFIVALGVLIAVHEYGHYRVAVACGVKVLRFSVGFGKPLLRWQPKGSPTEFVIGAFPLGGYVRMLDEREAPVEP
HERHLAFNTQPLRSRAAIVAAGPLANLLLAVLLYAAVNWSGVDEPKAYLASPVAGSVAEQAGLRGGELVVSAGLGEGDFE
PVRSFEDLRWTLTRGALDGQNVRLLLQPERGSTPREVLLRIDQLDVREADVQLYRRIGITAPWTRPVLGEVVPGGAAARA
GLRAGDVVLRLGSAAVVDGVQLRELIRASVQAGQPLTQVWRIERDGQPRDLEVTPEVAQEAGGAVGRVGAYVGAPPEMVN
VHYGPLEGLWKGTVRTWEVSVLTLRMMGRMVIGEASLKNLSGPLTIADYAGRSASMGLTQYLSFLALISVSLGVLNLLPL
PVLDGGHLMYYLWEGVTGRGVSEAWMERLQRTGVAVLLLMMSIALFNDLTRLFG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=459, Percent_Identity=40.0871459694989, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48929; Mature: 48929

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTVVAFIVALGVLIAVHEYGHYRVAVACGVKVLRFSVGFGKPLLRWQPKGSPTEFVIG
CHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHEECCCCCCCEEECCCCCCCEEEEE
AFPLGGYVRMLDEREAPVEPHERHLAFNTQPLRSRAAIVAAGPLANLLLAVLLYAAVNWS
EECCCHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCEEEECCHHHHHHHHHHHHHHCCCC
GVDEPKAYLASPVAGSVAEQAGLRGGELVVSAGLGEGDFEPVRSFEDLRWTLTRGALDGQ
CCCCCHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
NVRLLLQPERGSTPREVLLRIDQLDVREADVQLYRRIGITAPWTRPVLGEVVPGGAAARA
CEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHC
GLRAGDVVLRLGSAAVVDGVQLRELIRASVQAGQPLTQVWRIERDGQPRDLEVTPEVAQE
CCCCCHHHEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECHHHHHH
AGGAVGRVGAYVGAPPEMVNVHYGPLEGLWKGTVRTWEVSVLTLRMMGRMVIGEASLKNL
CCCCHHHHCHHCCCCHHEEEEECCCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHC
SGPLTIADYAGRSASMGLTQYLSFLALISVSLGVLNLLPLPVLDGGHLMYYLWEGVTGRG
CCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCC
VSEAWMERLQRTGVAVLLLMMSIALFNDLTRLFG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLTVVAFIVALGVLIAVHEYGHYRVAVACGVKVLRFSVGFGKPLLRWQPKGSPTEFVIG
CHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHEECCCCCCCEEECCCCCCCEEEEE
AFPLGGYVRMLDEREAPVEPHERHLAFNTQPLRSRAAIVAAGPLANLLLAVLLYAAVNWS
EECCCHHHHHHCCCCCCCCCCCCEEECCCCCHHHCCEEEECCHHHHHHHHHHHHHHCCCC
GVDEPKAYLASPVAGSVAEQAGLRGGELVVSAGLGEGDFEPVRSFEDLRWTLTRGALDGQ
CCCCCHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
NVRLLLQPERGSTPREVLLRIDQLDVREADVQLYRRIGITAPWTRPVLGEVVPGGAAARA
CEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHC
GLRAGDVVLRLGSAAVVDGVQLRELIRASVQAGQPLTQVWRIERDGQPRDLEVTPEVAQE
CCCCCHHHEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCEEECHHHHHH
AGGAVGRVGAYVGAPPEMVNVHYGPLEGLWKGTVRTWEVSVLTLRMMGRMVIGEASLKNL
CCCCHHHHCHHCCCCHHEEEEECCCCCHHHCCCCEEEEHHHHHHHHHHHHHHCCHHHHHC
SGPLTIADYAGRSASMGLTQYLSFLALISVSLGVLNLLPLPVLDGGHLMYYLWEGVTGRG
CCCEEEHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEEEECCCCCCC
VSEAWMERLQRTGVAVLLLMMSIALFNDLTRLFG
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]