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The map label for this gene is hupB [H]

Identifier: 222110394

GI number: 222110394

Start: 1245921

End: 1246193

Strand: Direct

Name: hupB [H]

Synonym: Dtpsy_1187

Alternate gene names: 222110394

Gene position: 1245921-1246193 (Clockwise)

Preceding gene: 222110393

Following gene: 222110395

Centisome position: 32.82

GC content: 54.58

Gene sequence:

>273_bases
GTGAATAAAACCGAATTGATTGAGCACATCGCCAACAACGCTGATATCTCCAAGGCTGCAGCTGCGCGCGCACTGGAGTC
CACGATCGAAGCGGTTAAGAAGACTCTCAAGAAAGGCGGCACGGTGTCGCTCGTCGGTTTCGGCACATTCGCCGTCGGCA
AGCGCGCTGCGCGCACTGGTCGTAATCCCCGCACGGGCGCTACCATTAAAATCAAGGCTGCTAAAGTTCCAAAGTTCCGT
CCAGGCAAAGCACTGAAAGATGCTTTGAACTGA

Upstream 100 bases:

>100_bases
TTCCCTCCGCCTCTGCCTTTCGGACCGCTTCCGTTGCAGGGGGCGCGGAGGCCAGATTTGCATAAAGACATTCATCCACT
CTTTTCCCGAGAGGCTTCTT

Downstream 100 bases:

>100_bases
TTGTGAAATATGGGGGGTGCTTAGCTCAGTTGGTAGAGCGGCGCCCTTACAAGGCGTAGGTCAGCGGTTCGACCCCGTTA
GCACCCACCACCCCATTCAA

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKTELIEHIANNADISKAAAARALESTIEAVKKTLKKGGTVSLVGFGTFAVGKRAARTGRNPRTGATIKIKAAKVPKFR
PGKALKDALN

Sequences:

>Translated_90_residues
MNKTELIEHIANNADISKAAAARALESTIEAVKKTLKKGGTVSLVGFGTFAVGKRAARTGRNPRTGATIKIKAAKVPKFR
PGKALKDALN
>Mature_90_residues
MNKTELIEHIANNADISKAAAARALESTIEAVKKTLKKGGTVSLVGFGTFAVGKRAARTGRNPRTGATIKIKAAKVPKFR
PGKALKDALN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=67.7777777777778, Blast_Score=120, Evalue=2e-29,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=61.7977528089888, Blast_Score=106, Evalue=3e-25,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=39.5604395604396, Blast_Score=76, Evalue=4e-16,
Organism=Escherichia coli, GI1788005, Length=86, Percent_Identity=38.3720930232558, Blast_Score=68, Evalue=1e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9457; Mature: 9457

Theoretical pI: Translated: 11.62; Mature: 11.62

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTELIEHIANNADISKAAAARALESTIEAVKKTLKKGGTVSLVGFGTFAVGKRAARTG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
RNPRTGATIKIKAAKVPKFRPGKALKDALN
CCCCCCCEEEEEECCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MNKTELIEHIANNADISKAAAARALESTIEAVKKTLKKGGTVSLVGFGTFAVGKRAARTG
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
RNPRTGATIKIKAAKVPKFRPGKALKDALN
CCCCCCCEEEEEECCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]