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The map label for this gene is uxuR [H]

Identifier: 222110370

GI number: 222110370

Start: 1225135

End: 1225830

Strand: Direct

Name: uxuR [H]

Synonym: Dtpsy_1162

Alternate gene names: 222110370

Gene position: 1225135-1225830 (Clockwise)

Preceding gene: 222110367

Following gene: 222110381

Centisome position: 32.27

GC content: 65.52

Gene sequence:

>696_bases
ATGAATAACCGCTTCACACTCCCACAGGCGCCGCGGCGTTCGCTCGTCGATTCGACGATTGAGCTGATCCGCGGCCAGAT
CGAGGGAGGCGCCTGGAAGGTCGGCGAGCGCATCCCCAGGGAGCAGGAACTGGCCGAGATGCTGGAGGTTGGCCGCAACA
CGGTGCGGGAAGCCATTCGCGTGCTCTCGCACGGCCAGGTCCTGGAAGTCCGCCAGGGTGATGGCACCTACGTGCGAACC
AATATCGATCCGGCCGAGGTCATGCGCCGTGTCGGGCGTTCCGGCTTGCGAGAGCACTTCGCGTTGCGCTGCATGCTGGA
AACCGAGGCGGCCAGGTTGGCCGCGGTGCATCGGTCCAAGGCGGACGTTGGGCTGCTGCGCCGACTGTTGAAGGCCCGCG
GCGAGCAGGAGCAACACGCATCGAGCGCGGCCTTTGCCGAGGCCGATACGGCTTTCCACTGCGCGATCGCCGGGATGTGC
GGCAACGGCGCGCTGGCTGAGCTGTACCGCTACTTCGCGAACTCGGTCCGCATGAACACGCTGACTGCGCTGAAGGACAA
GGAACTGCCCGAGCCGGGTCTCGCGACCCATGAGGCGATCGTGGATGCTATCGAGCGCCAGGATGGAGAAGCAGCTGCGG
CGGCTGTGCGGAACGTGGTCGCTCCGCTGATTGCGGCACTTGAGAAATCGGGTTGA

Upstream 100 bases:

>100_bases
GCTCTTTTGTCAAATACATAGAATCATCCTATGTATAAGGCCTGAGTTGCTACAATCGAGGTCCGATGGGCTCCCGTCTC
TACGTCATTTGAGAACCGCG

Downstream 100 bases:

>100_bases
TCCGAGCGCGACTCCCGCGCTGGCAATGCCGCTTTCCATCGAGCAGCCGGTCGCCGGCCCCGTTGATCGGAACGCGGGTT
GTTTCCCGGAGAGCACGCGG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNNRFTLPQAPRRSLVDSTIELIRGQIEGGAWKVGERIPREQELAEMLEVGRNTVREAIRVLSHGQVLEVRQGDGTYVRT
NIDPAEVMRRVGRSGLREHFALRCMLETEAARLAAVHRSKADVGLLRRLLKARGEQEQHASSAAFAEADTAFHCAIAGMC
GNGALAELYRYFANSVRMNTLTALKDKELPEPGLATHEAIVDAIERQDGEAAAAAVRNVVAPLIAALEKSG

Sequences:

>Translated_231_residues
MNNRFTLPQAPRRSLVDSTIELIRGQIEGGAWKVGERIPREQELAEMLEVGRNTVREAIRVLSHGQVLEVRQGDGTYVRT
NIDPAEVMRRVGRSGLREHFALRCMLETEAARLAAVHRSKADVGLLRRLLKARGEQEQHASSAAFAEADTAFHCAIAGMC
GNGALAELYRYFANSVRMNTLTALKDKELPEPGLATHEAIVDAIERQDGEAAAAAVRNVVAPLIAALEKSG
>Mature_231_residues
MNNRFTLPQAPRRSLVDSTIELIRGQIEGGAWKVGERIPREQELAEMLEVGRNTVREAIRVLSHGQVLEVRQGDGTYVRT
NIDPAEVMRRVGRSGLREHFALRCMLETEAARLAAVHRSKADVGLLRRLLKARGEQEQHASSAAFAEADTAFHCAIAGMC
GNGALAELYRYFANSVRMNTLTALKDKELPEPGLATHEAIVDAIERQDGEAAAAAVRNVVAPLIAALEKSG

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=207, Percent_Identity=32.3671497584541, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082208, Length=218, Percent_Identity=29.3577981651376, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=26.8867924528302, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25260; Mature: 25260

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRFTLPQAPRRSLVDSTIELIRGQIEGGAWKVGERIPREQELAEMLEVGRNTVREAIR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLSHGQVLEVRQGDGTYVRTNIDPAEVMRRVGRSGLREHFALRCMLETEAARLAAVHRSK
HHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADVGLLRRLLKARGEQEQHASSAAFAEADTAFHCAIAGMCGNGALAELYRYFANSVRMNT
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LTALKDKELPEPGLATHEAIVDAIERQDGEAAAAAVRNVVAPLIAALEKSG
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNRFTLPQAPRRSLVDSTIELIRGQIEGGAWKVGERIPREQELAEMLEVGRNTVREAIR
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VLSHGQVLEVRQGDGTYVRTNIDPAEVMRRVGRSGLREHFALRCMLETEAARLAAVHRSK
HHCCCCEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ADVGLLRRLLKARGEQEQHASSAAFAEADTAFHCAIAGMCGNGALAELYRYFANSVRMNT
CCHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LTALKDKELPEPGLATHEAIVDAIERQDGEAAAAAVRNVVAPLIAALEKSG
HHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]