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The map label for this gene is cobP [H]

Identifier: 222110228

GI number: 222110228

Start: 1055468

End: 1056067

Strand: Direct

Name: cobP [H]

Synonym: Dtpsy_1014

Alternate gene names: 222110228

Gene position: 1055468-1056067 (Clockwise)

Preceding gene: 222110227

Following gene: 222110229

Centisome position: 27.8

GC content: 69.83

Gene sequence:

>600_bases
ATGAACGCGGCGCCGCAGACCATCGCCCGCAGTGAACTCATCCTGGGTGGACAAAAGAGCGGCAAGTCGCGCCGCGCCGA
ACTGCTGGCGCGCCAGTGGCTGCAGGCCGCGCCGGCACACCGCGCGTTGCTGCTGGCCACCGGCCAGCCGTGGGACGACG
AGATGCGTGCGCGCATTGCCCGCCACCAGCGCGAGCGTGCCGAGCGTGTGCCCGGCCTGCAGACCGTGGAAGAGCCGCGC
GATCTGGCCCACGCCCTGGCGTGCCACAGCACCCCACAGACCCTGATCGTCGTGGACTGCCTCACCCTGTGGCTCACCAA
CTGGCTCATGCCGGCCGACCCCCAAGATGTAGAGCAAAAACAGCCTCTAGCGCCCGACTGGCAAGCGCAGGCAGCTCACT
TTTTTGAAGCGTTGACGCACGCGCCCGGCCCCGTGGTGCTGGTGGGCAACGAGATCGGCCTGGGCGTGATCCCCCTGGGG
CGCGAAGTGCGCGCCTTCGTGGACGCGCTGGGCGCCCTGAACCAGCGCGCGGCGGCAGCCTGCCAGCGCGTCACGCTGAT
GGCGGCGGGCCTGCCGCTTACCCTGAAGGACGTACCATGA

Upstream 100 bases:

>100_bases
CCGTGTACCGCCACGGCAGCATCCACGCGAGTTACTTTCACGCATGGTTTGCATCCAGCCCGCAGGCGACCGCAGCCTTG
CTGGGCGCGGAGGCGGGGCC

Downstream 100 bases:

>100_bases
TGCCTCTTCGCTGGCGCCGCCAGCTTGCTGCCGCCGGCTGGATGCTGGGTCTGCTGCTGGCCTTGCCCAGCGCCCACGCG
GTAACCATCACCGACGACCG

Product: cobalbumin biosynthesis protein

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNAAPQTIARSELILGGQKSGKSRRAELLARQWLQAAPAHRALLLATGQPWDDEMRARIARHQRERAERVPGLQTVEEPR
DLAHALACHSTPQTLIVVDCLTLWLTNWLMPADPQDVEQKQPLAPDWQAQAAHFFEALTHAPGPVVLVGNEIGLGVIPLG
REVRAFVDALGALNQRAAAACQRVTLMAAGLPLTLKDVP

Sequences:

>Translated_199_residues
MNAAPQTIARSELILGGQKSGKSRRAELLARQWLQAAPAHRALLLATGQPWDDEMRARIARHQRERAERVPGLQTVEEPR
DLAHALACHSTPQTLIVVDCLTLWLTNWLMPADPQDVEQKQPLAPDWQAQAAHFFEALTHAPGPVVLVGNEIGLGVIPLG
REVRAFVDALGALNQRAAAACQRVTLMAAGLPLTLKDVP
>Mature_199_residues
MNAAPQTIARSELILGGQKSGKSRRAELLARQWLQAAPAHRALLLATGQPWDDEMRARIARHQRERAERVPGLQTVEEPR
DLAHALACHSTPQTLIVVDCLTLWLTNWLMPADPQDVEQKQPLAPDWQAQAAHFFEALTHAPGPVVLVGNEIGLGVIPLG
REVRAFVDALGALNQRAAAACQRVTLMAAGLPLTLKDVP

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=188, Percent_Identity=34.5744680851064, Blast_Score=96, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 21692; Mature: 21692

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAPQTIARSELILGGQKSGKSRRAELLARQWLQAAPAHRALLLATGQPWDDEMRARIA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
RHQRERAERVPGLQTVEEPRDLAHALACHSTPQTLIVVDCLTLWLTNWLMPADPQDVEQK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHC
QPLAPDWQAQAAHFFEALTHAPGPVVLVGNEIGLGVIPLGREVRAFVDALGALNQRAAAA
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
CQRVTLMAAGLPLTLKDVP
HHHHHHHHCCCCEEECCCC
>Mature Secondary Structure
MNAAPQTIARSELILGGQKSGKSRRAELLARQWLQAAPAHRALLLATGQPWDDEMRARIA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
RHQRERAERVPGLQTVEEPRDLAHALACHSTPQTLIVVDCLTLWLTNWLMPADPQDVEQK
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHC
QPLAPDWQAQAAHFFEALTHAPGPVVLVGNEIGLGVIPLGREVRAFVDALGALNQRAAAA
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHH
CQRVTLMAAGLPLTLKDVP
HHHHHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]