Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 222110117

GI number: 222110117

Start: 926334

End: 927245

Strand: Direct

Name: xerD [H]

Synonym: Dtpsy_0903

Alternate gene names: 222110117

Gene position: 926334-927245 (Clockwise)

Preceding gene: 222110116

Following gene: 222110118

Centisome position: 24.4

GC content: 69.08

Gene sequence:

>912_bases
ATGGTTTTCGCCATGTTGCCCGACAGCCAGAACGCCATAGACCCCTTCATCGACGCCCTGTGGCTGGAGGACGGCCTGTC
GCGCAACACGCTGGCCGCCTACCGCCGGGACCTCACGCTGTATGCCCAATGGCTGGCGCAGCAGAACCCTCCGCTGGCGC
TGGATGCCACGGCCGAGCACCACCTGCAGGGCTACTTCGCTGCCCGCCACGCGCAAACGCGCGCCACGTCGGCCAACCGC
CGCCTCACCGTGCTGCGGCGCTACTTCCACTGGGCATTGCGCGAGCGGCGCATCGCAGCCGACCCCACAGTGCGCCTGCA
AGCCGCGCGCCAGCCGCTGCGCGTGCCCAAGACGCTGACGCAGGCGCAGGTGGAGGCCCTGTTGCATGCGCCGGACGATG
CCACGCCGCTGGGCCTGCGCGACCGCACCATGTTGGAGCTGATGTACGCGAGCGGCCTGCGCGTGAGCGAGCTGGTCACG
CTGAAAACCTTCCACCTGGGGCTGGCTGAAGGCGTGCTGCGCGTCATGGGCAAGGGCGGCAAGGAGCGGCTGGTGCCCTT
TGGCGAAGAGGCGCACCGCTGGCTGCAGCGCTACCTGGCCGAGGGGCGTGGCGCCATCCTGGGCGGGCAGCAAACGGATG
ACCTGTTCGTCACGCAGCGCGGCGCGGCCATGTCGCGCGTGATGTTCTGGGTCATCGTCAAGAAATGCGCGCAGGCTGCA
GGCATCACCGCGCCGCTGTCGCCCCACACGCTGCGCCATGCCTTTGCCACGCACCTGTTGAACCACGGTGCGGACCTGCG
CGTGGTGCAACTGCTGCTGGGCCACGCCGACATTTCCACCACCACCATCTACACCCACGTGGCGCGCGAGCGGCTGAAGG
CGCTGCATGCGCAGCACCATCCGCGCGGTTGA

Upstream 100 bases:

>100_bases
TGTACAAGCAGGTGGTGCAAAAGCAGAAGCTCACGCTGGAATAAGCGCGCCCCCAGCCCTCTGAAAAACGCCCGCCTGCC
GCGGGCGTTTTTTTGATGCT

Downstream 100 bases:

>100_bases
AGGGGCATGGCGCGGAGTGCCGGCGGACAGCGGCAAACGGGTGAAAAATCGCGCTCTTTCTTGAAACTCTGGAGTTGCAA
TGACAGATTCCGTGCGCCGT

Product: tyrosine recombinase xerd

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MVFAMLPDSQNAIDPFIDALWLEDGLSRNTLAAYRRDLTLYAQWLAQQNPPLALDATAEHHLQGYFAARHAQTRATSANR
RLTVLRRYFHWALRERRIAADPTVRLQAARQPLRVPKTLTQAQVEALLHAPDDATPLGLRDRTMLELMYASGLRVSELVT
LKTFHLGLAEGVLRVMGKGGKERLVPFGEEAHRWLQRYLAEGRGAILGGQQTDDLFVTQRGAAMSRVMFWVIVKKCAQAA
GITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTTIYTHVARERLKALHAQHHPRG

Sequences:

>Translated_303_residues
MVFAMLPDSQNAIDPFIDALWLEDGLSRNTLAAYRRDLTLYAQWLAQQNPPLALDATAEHHLQGYFAARHAQTRATSANR
RLTVLRRYFHWALRERRIAADPTVRLQAARQPLRVPKTLTQAQVEALLHAPDDATPLGLRDRTMLELMYASGLRVSELVT
LKTFHLGLAEGVLRVMGKGGKERLVPFGEEAHRWLQRYLAEGRGAILGGQQTDDLFVTQRGAAMSRVMFWVIVKKCAQAA
GITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTTIYTHVARERLKALHAQHHPRG
>Mature_303_residues
MVFAMLPDSQNAIDPFIDALWLEDGLSRNTLAAYRRDLTLYAQWLAQQNPPLALDATAEHHLQGYFAARHAQTRATSANR
RLTVLRRYFHWALRERRIAADPTVRLQAARQPLRVPKTLTQAQVEALLHAPDDATPLGLRDRTMLELMYASGLRVSELVT
LKTFHLGLAEGVLRVMGKGGKERLVPFGEEAHRWLQRYLAEGRGAILGGQQTDDLFVTQRGAAMSRVMFWVIVKKCAQAA
GITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTTIYTHVARERLKALHAQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=54.2662116040956, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI1790244, Length=298, Percent_Identity=35.2348993288591, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1790768, Length=170, Percent_Identity=32.9411764705882, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790767, Length=168, Percent_Identity=27.3809523809524, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33947; Mature: 33947

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFAMLPDSQNAIDPFIDALWLEDGLSRNTLAAYRRDLTLYAQWLAQQNPPLALDATAEH
CEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHH
HLQGYFAARHAQTRATSANRRLTVLRRYFHWALRERRIAADPTVRLQAARQPLRVPKTLT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHH
QAQVEALLHAPDDATPLGLRDRTMLELMYASGLRVSELVTLKTFHLGLAEGVLRVMGKGG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KERLVPFGEEAHRWLQRYLAEGRGAILGGQQTDDLFVTQRGAAMSRVMFWVIVKKCAQAA
CCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHC
GITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTTIYTHVARERLKALHAQHH
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
PRG
CCC
>Mature Secondary Structure
MVFAMLPDSQNAIDPFIDALWLEDGLSRNTLAAYRRDLTLYAQWLAQQNPPLALDATAEH
CEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHH
HLQGYFAARHAQTRATSANRRLTVLRRYFHWALRERRIAADPTVRLQAARQPLRVPKTLT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCHHHHH
QAQVEALLHAPDDATPLGLRDRTMLELMYASGLRVSELVTLKTFHLGLAEGVLRVMGKGG
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
KERLVPFGEEAHRWLQRYLAEGRGAILGGQQTDDLFVTQRGAAMSRVMFWVIVKKCAQAA
CCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHC
GITAPLSPHTLRHAFATHLLNHGADLRVVQLLLGHADISTTTIYTHVARERLKALHAQHH
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
PRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]