Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 222109919

GI number: 222109919

Start: 732935

End: 734038

Strand: Direct

Name: aroB [H]

Synonym: Dtpsy_0704

Alternate gene names: 222109919

Gene position: 732935-734038 (Clockwise)

Preceding gene: 222109918

Following gene: 222109920

Centisome position: 19.31

GC content: 61.96

Gene sequence:

>1104_bases
ATGGCAAAGATGGCTACGGTACAGATCGAACTAGGGGATCGGGGCTACGCCATCTATATCGGCAACGGTCTGCTGGAGAA
TGCAGGCACCTACAAGGGCTTGCCCGCAGCGTACGCCGCGCTCATTGTCAGCAATACCTCGGTTGCACCGTTGTATGCAC
AGAGATTGCGGAATGCCTTGCGGATGCAATATGCGCAGCTGCACGAAGTCGTCTTGCCAGATGGCGAGTCACACAAGGAT
TGGCATACGCTGAATCTGATCTTTGACGGTTTGCTGCAGCACGGCTGCGACCGTAGAACTGTTTTATTCGCCTTGGGCGG
CGGTGTCATCGGCGACATGACCGGTTTCGCCGCGGCGTGCTACATGCGCGGCGTGCCCTTCGTGCAAGTGCCCACCACAT
TGCTGGCGCAAGTGGATTCGTCGGTGGGCGGCAAGACTGCCATCAACCATCCGCTGGGTAAGAACATGATCGGCGCGTTC
TATCAGCCTCAGTTGGTGGTATGTGATCTGGACACGTTGGACACTTTGCCGGCCCGCGAGTTGGCGGCGGGCCTGGCCGA
GGTGATCAAGTACGGGCCTATCGCAGACATGGAGCTGTTTGCCTGGCTCGAGGCCCACATGGACGCGCTCGTTGCGCGGG
AGCGCGGCGCGCTGGCCCATGTGGTCAAGCGCAGCTGCGAGATCAAGGCGGCGGTGGTAGGCGCGGATGAACGCGAAGCC
GGGCTGCGTGCCATTTTGAATTTCGGCCATACCTTTGGCCATGCCATCGAGGCGGGCATGGGCTACGGCGTGTGGCTGCA
TGGCGAAGGGGTTGCCGCAGGCATGGTGATGGCCGCGCATCTATCGCAGCGGCTGGGTTTGGTGGACGGCTCTTTCGTTG
AACGCCTGACGCGCCTGATCGAGCGCGCCGGTCTGCCCACACGGGGGCCGGTGCTTGACGCGCAGGACAATGCGGGGCGC
TATCTGGAACTCATGCGCGTGGACAAGAAGGCAGAAGGCGGTGAGATCCGCTTCGTGCTGATCGACGGACCCGGCAAAGC
CATCATGCGCGCCGCGCCGGATGCGCTGGTGCGCGAAGTCATCGACCAGTGCTGCGCATCCTGA

Upstream 100 bases:

>100_bases
TCATCACAGATCGCGGGCCGGTACGCTGAGGCACGTGTTCAGTTAGTTCGACAGGGGGTGGTTCACCCCCTGTTTTTATT
GGGTAGATGGAGTGGCATGT

Downstream 100 bases:

>100_bases
TGTTTACTATAAAAATAGTAGCTGATTGCGCTTTTCTGGTGGGCGTTATGGGGCTGTTTGGTGCTTGAGACGCATTTGGC
GTCGTATGCCTGTCATTCGG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MAKMATVQIELGDRGYAIYIGNGLLENAGTYKGLPAAYAALIVSNTSVAPLYAQRLRNALRMQYAQLHEVVLPDGESHKD
WHTLNLIFDGLLQHGCDRRTVLFALGGGVIGDMTGFAAACYMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAF
YQPQLVVCDLDTLDTLPARELAAGLAEVIKYGPIADMELFAWLEAHMDALVARERGALAHVVKRSCEIKAAVVGADEREA
GLRAILNFGHTFGHAIEAGMGYGVWLHGEGVAAGMVMAAHLSQRLGLVDGSFVERLTRLIERAGLPTRGPVLDAQDNAGR
YLELMRVDKKAEGGEIRFVLIDGPGKAIMRAAPDALVREVIDQCCAS

Sequences:

>Translated_367_residues
MAKMATVQIELGDRGYAIYIGNGLLENAGTYKGLPAAYAALIVSNTSVAPLYAQRLRNALRMQYAQLHEVVLPDGESHKD
WHTLNLIFDGLLQHGCDRRTVLFALGGGVIGDMTGFAAACYMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAF
YQPQLVVCDLDTLDTLPARELAAGLAEVIKYGPIADMELFAWLEAHMDALVARERGALAHVVKRSCEIKAAVVGADEREA
GLRAILNFGHTFGHAIEAGMGYGVWLHGEGVAAGMVMAAHLSQRLGLVDGSFVERLTRLIERAGLPTRGPVLDAQDNAGR
YLELMRVDKKAEGGEIRFVLIDGPGKAIMRAAPDALVREVIDQCCAS
>Mature_366_residues
AKMATVQIELGDRGYAIYIGNGLLENAGTYKGLPAAYAALIVSNTSVAPLYAQRLRNALRMQYAQLHEVVLPDGESHKDW
HTLNLIFDGLLQHGCDRRTVLFALGGGVIGDMTGFAAACYMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAFY
QPQLVVCDLDTLDTLPARELAAGLAEVIKYGPIADMELFAWLEAHMDALVARERGALAHVVKRSCEIKAAVVGADEREAG
LRAILNFGHTFGHAIEAGMGYGVWLHGEGVAAGMVMAAHLSQRLGLVDGSFVERLTRLIERAGLPTRGPVLDAQDNAGRY
LELMRVDKKAEGGEIRFVLIDGPGKAIMRAAPDALVREVIDQCCAS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=53.8674033149171, Blast_Score=356, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6320332, Length=340, Percent_Identity=40.8823529411765, Blast_Score=217, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39359; Mature: 39228

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKMATVQIELGDRGYAIYIGNGLLENAGTYKGLPAAYAALIVSNTSVAPLYAQRLRNAL
CCCEEEEEEEECCCEEEEEECCCEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RMQYAQLHEVVLPDGESHKDWHTLNLIFDGLLQHGCDRRTVLFALGGGVIGDMTGFAAAC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
YMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPQLVVCDLDTLDTLPARE
HHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCHHH
LAAGLAEVIKYGPIADMELFAWLEAHMDALVARERGALAHVVKRSCEIKAAVVGADEREA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCHHHH
GLRAILNFGHTFGHAIEAGMGYGVWLHGEGVAAGMVMAAHLSQRLGLVDGSFVERLTRLI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ERAGLPTRGPVLDAQDNAGRYLELMRVDKKAEGGEIRFVLIDGPGKAIMRAAPDALVREV
HHCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHCCHHHHHHHH
IDQCCAS
HHHHHCC
>Mature Secondary Structure 
AKMATVQIELGDRGYAIYIGNGLLENAGTYKGLPAAYAALIVSNTSVAPLYAQRLRNAL
CCEEEEEEEECCCEEEEEECCCEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RMQYAQLHEVVLPDGESHKDWHTLNLIFDGLLQHGCDRRTVLFALGGGVIGDMTGFAAAC
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHH
YMRGVPFVQVPTTLLAQVDSSVGGKTAINHPLGKNMIGAFYQPQLVVCDLDTLDTLPARE
HHCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCHHH
LAAGLAEVIKYGPIADMELFAWLEAHMDALVARERGALAHVVKRSCEIKAAVVGADEREA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCHHHH
GLRAILNFGHTFGHAIEAGMGYGVWLHGEGVAAGMVMAAHLSQRLGLVDGSFVERLTRLI
HHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ERAGLPTRGPVLDAQDNAGRYLELMRVDKKAEGGEIRFVLIDGPGKAIMRAAPDALVREV
HHCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHCCHHHHHHHH
IDQCCAS
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA