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The map label for this gene is pilQ [H]

Identifier: 222109918

GI number: 222109918

Start: 730773

End: 732863

Strand: Direct

Name: pilQ [H]

Synonym: Dtpsy_0703

Alternate gene names: 222109918

Gene position: 730773-732863 (Clockwise)

Preceding gene: 222109917

Following gene: 222109919

Centisome position: 19.25

GC content: 52.8

Gene sequence:

>2091_bases
ATGATTCAAGAGAAGCTTCGTTTACACGCGTACTGGCGGATGTTGGGAGCCGCAGTTGTGGCTGCGCTGACGGTGTCTGT
GGCGCAAGCTCGCGGATCTATTGATTCCATCTCTGGTTTTTTGCAAGGTGGCGCCGAAGTTCTGCGGATTGAATTTTCTG
AGCCGCAAGCAGAATTGCCCACTGGGTTCTCTATCCAAAACCCTGCGCGCATTGCACTGGACTTTCCTGGAGTGAGCAAT
GGGACCGGGCGCTCATCAATAGATATCAATCAGGGGAATGTCAAGTCTGCCAACATTGTGCAAGCAGGAGCGCGGGCGCG
CGTAGTCTTGAATCTCAAGCAGCCCACTTCTTACCGCGCAGAGTTGCAAGGCAAGACAGTCCTGGTGCTGTTGGATGCTG
CGTCCTCGGCTGCAAAGATGCCTCCTCCTCAGGTGACGACATTCGCAGAAAGTCAAAATATTGACAATTTGCCGCTGAAG
GATCTTGATTTTCGACGTGGAACAGATGGGGCCGGTCGTATTGTTGTTGGGTTGCCTAACAATCAGGTGGGCGTCGATTT
GCAGCAGCAGGGTAAGGGGCTGATTGTTGATTTCCTGCGTTCATCGTTGCCCGAAGGCCTGCGCCGTAAACTGGACGTTT
CTGACTTCGGTACGCCCGTGCAAACCATTACTGCATCACAACAGGGTGAGCGTGTGCGTCTGACAATTGACCCTGTTGGT
GAATGGGAGCATAGCGCTTATCAAAGTGATAATCAGTTTGTAGTCGAGGTGCGGCCGAAGAAGGTTGATTTGACTAAATT
GACACAAGGTCCTGCATACTCTGGAGAGAAACTCTCTCTGAATTTTCAAAATATTGAAGTTCGTTCGTTGCTGCAAGTGA
TTGCGGATTTTACTAATTTCAATATTGTTACCTCGGACACTGTTACCGGTGCTTTGACCTTGCGGCTGAAGGATGTTCCC
TGGGATCAGGCTCTCCAGATCATCATGGACGCCAAGGGGCTTGGCATGCGCAAGTCTGGCACGGTACTGTGGATCGCGCC
TAAAGACGAAATAGACGAGCGCACAAAGAAGGATTACGAAGCCGCTTTGGCGATTCAGAAATTGGAGCCTTTGCGGACCC
AGGCTTTCCAATTGAATTATGCAAAAGCCGCCGACATGGTCACCCAACTGACCATGAGCAGTCAGGGTGGATCGTCCACG
AGCGGTTACTCCAATCGATTCCTGTCGGATCGCGGGAGTGCAATCTCGGAGCCGCGCACCAATCAGCTATTTGTTACGGA
TACTTCGGCCAAACTTGAAGAAGTTCGCCAGTTGTTGGCGACGCTTGATGTACCGGTGCGGCAGGTGATGATCGAGGCGC
GTATCGTGGAAGCGCGGGATACGTTTGGTCGTTCCTTGGGGGTGCGGCTGGGAGGAGGGTCGCGCACGGGCGGAAGTGCA
GTTGGCGGTACCTACGATAATGTGGCCGGCCCCACTGGGGGGAGTGGCATGTCACCGTTCGTTAGCCTGCCTGCATCTTT
ATCAGGGGTCTCCACTGTTGGATCATTCGCATTGTCGATCTTCAATTCCAACGCCAGTCGCTTCCTCTCTCTGGAGTTGT
CTGCCATGGAAGCGGATGGGCAGGGCAAGATCGTTTCCAGTCCGCGTTTAATTACGGCTGATCAGACCAAGGCGCTCATC
GAACAGGGGACGGAATATCCTTATTCGGTTACCGCTCCGAACGGTGCGACAACCATCGCCTTTAAGAAAGCCGTATTGAA
ACTGGAAGTGACGCCTCAGATCACCCCTGAGGGCAACATCATTCTTGATCTGGACGTCAACAAGGACAGTCGAGGAGAGA
GCACCACGCAGGGAGTGGCCATCGATACTAAGCACATCAAGACCCAAGTGTTGATCGAGAACGGCGGCACTGTCGTGATC
GGGGGTATTTTTGAGATGGAAGAGACCAACCAAGAGAACAAAATACCTGTCTTGGGTGACGTTCCCGTGGTCGGGAATCT
ATTCAAAAATAGAACGAAGGAGTCCACCAAGCGGGAGATGCTGGTGTTTATTACTCCCAAGGTCATCACAGATCGCGGGC
CGGTACGCTGA

Upstream 100 bases:

>100_bases
AGACCAATATGCGCCTGCGAGAGATTGTCCAAGATCCGACGGGCGATTGGGTAGAGCGTATGACAACACTGGATCTGCAA
GAGGGGAATGAGGTGAAGAA

Downstream 100 bases:

>100_bases
GGCACGTGTTCAGTTAGTTCGACAGGGGGTGGTTCACCCCCTGTTTTTATTGGGTAGATGGAGTGGCATGTATGGCAAAG
ATGGCTACGGTACAGATCGA

Product: type IV pilus secretin pilq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MIQEKLRLHAYWRMLGAAVVAALTVSVAQARGSIDSISGFLQGGAEVLRIEFSEPQAELPTGFSIQNPARIALDFPGVSN
GTGRSSIDINQGNVKSANIVQAGARARVVLNLKQPTSYRAELQGKTVLVLLDAASSAAKMPPPQVTTFAESQNIDNLPLK
DLDFRRGTDGAGRIVVGLPNNQVGVDLQQQGKGLIVDFLRSSLPEGLRRKLDVSDFGTPVQTITASQQGERVRLTIDPVG
EWEHSAYQSDNQFVVEVRPKKVDLTKLTQGPAYSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVP
WDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDERTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLTMSSQGGSST
SGYSNRFLSDRGSAISEPRTNQLFVTDTSAKLEEVRQLLATLDVPVRQVMIEARIVEARDTFGRSLGVRLGGGSRTGGSA
VGGTYDNVAGPTGGSGMSPFVSLPASLSGVSTVGSFALSIFNSNASRFLSLELSAMEADGQGKIVSSPRLITADQTKALI
EQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSRGESTTQGVAIDTKHIKTQVLIENGGTVVI
GGIFEMEETNQENKIPVLGDVPVVGNLFKNRTKESTKREMLVFITPKVITDRGPVR

Sequences:

>Translated_696_residues
MIQEKLRLHAYWRMLGAAVVAALTVSVAQARGSIDSISGFLQGGAEVLRIEFSEPQAELPTGFSIQNPARIALDFPGVSN
GTGRSSIDINQGNVKSANIVQAGARARVVLNLKQPTSYRAELQGKTVLVLLDAASSAAKMPPPQVTTFAESQNIDNLPLK
DLDFRRGTDGAGRIVVGLPNNQVGVDLQQQGKGLIVDFLRSSLPEGLRRKLDVSDFGTPVQTITASQQGERVRLTIDPVG
EWEHSAYQSDNQFVVEVRPKKVDLTKLTQGPAYSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVP
WDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDERTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLTMSSQGGSST
SGYSNRFLSDRGSAISEPRTNQLFVTDTSAKLEEVRQLLATLDVPVRQVMIEARIVEARDTFGRSLGVRLGGGSRTGGSA
VGGTYDNVAGPTGGSGMSPFVSLPASLSGVSTVGSFALSIFNSNASRFLSLELSAMEADGQGKIVSSPRLITADQTKALI
EQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSRGESTTQGVAIDTKHIKTQVLIENGGTVVI
GGIFEMEETNQENKIPVLGDVPVVGNLFKNRTKESTKREMLVFITPKVITDRGPVR
>Mature_696_residues
MIQEKLRLHAYWRMLGAAVVAALTVSVAQARGSIDSISGFLQGGAEVLRIEFSEPQAELPTGFSIQNPARIALDFPGVSN
GTGRSSIDINQGNVKSANIVQAGARARVVLNLKQPTSYRAELQGKTVLVLLDAASSAAKMPPPQVTTFAESQNIDNLPLK
DLDFRRGTDGAGRIVVGLPNNQVGVDLQQQGKGLIVDFLRSSLPEGLRRKLDVSDFGTPVQTITASQQGERVRLTIDPVG
EWEHSAYQSDNQFVVEVRPKKVDLTKLTQGPAYSGEKLSLNFQNIEVRSLLQVIADFTNFNIVTSDTVTGALTLRLKDVP
WDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDERTKKDYEAALAIQKLEPLRTQAFQLNYAKAADMVTQLTMSSQGGSST
SGYSNRFLSDRGSAISEPRTNQLFVTDTSAKLEEVRQLLATLDVPVRQVMIEARIVEARDTFGRSLGVRLGGGSRTGGSA
VGGTYDNVAGPTGGSGMSPFVSLPASLSGVSTVGSFALSIFNSNASRFLSLELSAMEADGQGKIVSSPRLITADQTKALI
EQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNIILDLDVNKDSRGESTTQGVAIDTKHIKTQVLIENGGTVVI
GGIFEMEETNQENKIPVLGDVPVVGNLFKNRTKESTKREMLVFITPKVITDRGPVR

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=425, Percent_Identity=32.4705882352941, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082242, Length=350, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 74903; Mature: 74903

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQEKLRLHAYWRMLGAAVVAALTVSVAQARGSIDSISGFLQGGAEVLRIEFSEPQAELP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEECCCCCCCC
TGFSIQNPARIALDFPGVSNGTGRSSIDINQGNVKSANIVQAGARARVVLNLKQPTSYRA
CCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHH
ELQGKTVLVLLDAASSAAKMPPPQVTTFAESQNIDNLPLKDLDFRRGTDGAGRIVVGLPN
CCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
NQVGVDLQQQGKGLIVDFLRSSLPEGLRRKLDVSDFGTPVQTITASQQGERVRLTIDPVG
CCCCCCHHHCCCCCHHHHHHHHCCHHHHHHCCHHHCCCCCEEEECCCCCCEEEEEECCCC
EWEHSAYQSDNQFVVEVRPKKVDLTKLTQGPAYSGEKLSLNFQNIEVRSLLQVIADFTNF
CCCHHHHCCCCEEEEEECCCEECCEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
NIVTSDTVTGALTLRLKDVPWDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDERTKKDYE
EEEECCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
AALAIQKLEPLRTQAFQLNYAKAADMVTQLTMSSQGGSSTSGYSNRFLSDRGSAISEPRT
HHHHHHHHCHHHHHHEEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
NQLFVTDTSAKLEEVRQLLATLDVPVRQVMIEARIVEARDTFGRSLGVRLGGGSRTGGSA
CEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
VGGTYDNVAGPTGGSGMSPFVSLPASLSGVSTVGSFALSIFNSNASRFLSLELSAMEADG
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEEEEEECCC
QGKIVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNI
CCEEECCCEEEECHHHHHHHHCCCCCCEEEECCCCCEEEEEEEEEEEEEECCCCCCCCCE
ILDLDVNKDSRGESTTQGVAIDTKHIKTQVLIENGGTVVIGGIFEMEETNQENKIPVLGD
EEEEECCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCEEEC
VPVVGNLFKNRTKESTKREMLVFITPKVITDRGPVR
CCHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCCC
>Mature Secondary Structure
MIQEKLRLHAYWRMLGAAVVAALTVSVAQARGSIDSISGFLQGGAEVLRIEFSEPQAELP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEECCCCCCCC
TGFSIQNPARIALDFPGVSNGTGRSSIDINQGNVKSANIVQAGARARVVLNLKQPTSYRA
CCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEECCCCEEEEEEECCCCCCHH
ELQGKTVLVLLDAASSAAKMPPPQVTTFAESQNIDNLPLKDLDFRRGTDGAGRIVVGLPN
CCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
NQVGVDLQQQGKGLIVDFLRSSLPEGLRRKLDVSDFGTPVQTITASQQGERVRLTIDPVG
CCCCCCHHHCCCCCHHHHHHHHCCHHHHHHCCHHHCCCCCEEEECCCCCCEEEEEECCCC
EWEHSAYQSDNQFVVEVRPKKVDLTKLTQGPAYSGEKLSLNFQNIEVRSLLQVIADFTNF
CCCHHHHCCCCEEEEEECCCEECCEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCC
NIVTSDTVTGALTLRLKDVPWDQALQIIMDAKGLGMRKSGTVLWIAPKDEIDERTKKDYE
EEEECCCCEEEEEEEEECCCHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHH
AALAIQKLEPLRTQAFQLNYAKAADMVTQLTMSSQGGSSTSGYSNRFLSDRGSAISEPRT
HHHHHHHHCHHHHHHEEECHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCC
NQLFVTDTSAKLEEVRQLLATLDVPVRQVMIEARIVEARDTFGRSLGVRLGGGSRTGGSA
CEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
VGGTYDNVAGPTGGSGMSPFVSLPASLSGVSTVGSFALSIFNSNASRFLSLELSAMEADG
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHEEECCCCCEEEEEEEEEEECCC
QGKIVSSPRLITADQTKALIEQGTEYPYSVTAPNGATTIAFKKAVLKLEVTPQITPEGNI
CCEEECCCEEEECHHHHHHHHCCCCCCEEEECCCCCEEEEEEEEEEEEEECCCCCCCCCE
ILDLDVNKDSRGESTTQGVAIDTKHIKTQVLIENGGTVVIGGIFEMEETNQENKIPVLGD
EEEEECCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEEEEEEEECCCCCCCCCCEEEC
VPVVGNLFKNRTKESTKREMLVFITPKVITDRGPVR
CCHHHHHHHHCCCCCCCCCEEEEECCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]