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The map label for this gene is htrB [C]

Identifier: 222109900

GI number: 222109900

Start: 711400

End: 712275

Strand: Direct

Name: htrB [C]

Synonym: Dtpsy_0684

Alternate gene names: 222109900

Gene position: 711400-712275 (Clockwise)

Preceding gene: 222109898

Following gene: 222109901

Centisome position: 18.74

GC content: 70.89

Gene sequence:

>876_bases
ATGTCATCCCTCTTTCGGCTCGTTTCCGCGCTGCCCTTGTGGTTGCTGCATGTCATTGGCGCGGCGCTTGGCTGGGTGGC
GTTTTGCGCATCGCCCACCTACCGCCGCCGCTTCATCGACAACGCCGCGCGCGCGGGCTATGCCTTGCGTGACGTGCGTG
CGGCCATAGCGCACGCAGGGCGCATGGTGGCCGAGGCGCCGCGTCTGTGGCTGCGGCCCGAGCCGCCGGCCTGCGAGATA
CACGGGGCCGAATGCGTGCAACGGGCCTGGGGCCAAGGCCGCGGCATCGTGTTCCTCACGCCGCACATTGGCTGTTTCGA
GTTGTCGGTGCAGGCGGCGGCGCGGCGCTGGTCGCCGGAGCACGGCCCCATCACCATCCTGTACCGGCCCGCGCGCCAGC
GCTGGCTGGCCGAGGTGATGCAGACCGCGCGCAACCGCCCCGGCATCCAGGCCGTGCCCACCACGTTGCAGGGCGTGCGC
CAGATGATCAAGGCGCTGCGGCGCGGCGAGGCGGTGGGCCTGCTGCCTGACCAGGTGCCGCCGCAGGGGCTGGGGGTGTG
GTCGCCGTTCTTCGGCCGCCCGGCCTACACCATGACGCTGGCTGCGCGCCTGGTGCAGCAGACCGGTGCGGCGGTGATCC
TGGCGCGGTGCGAGCGCCTGCCACGCGGGCGCGGCTATGTGCTGCACCTGGAGGATTTGCCCCAGCCGCTGGCGCCTACA
CTCGACGCGGCCGTGCTGCAGCTCAACCAAGCCATGGAATACCTCATCCGCCAAAGCCCCGACCAATACCTGTGGGGCTA
TGCCCGCTACAAGCAGCCCCGCGCAGAGATGCATACCTCTGCCGGGACCGATGCGCCGCCGGAGGGCCGCGCATGA

Upstream 100 bases:

>100_bases
GTTGCCCAGAGCCTCATGGAGCCTCGGCGAACGCTTTAGCAGTTGTGTTTAACGTCGCCCTGCAAGTTGCTCATTTAACT
CGGCGACGACCGTCATTGTA

Downstream 100 bases:

>100_bases
TGGCGCGCGCGGGCATCGCGCTGCTGAATCTGCTGGGTCGCCTGCCGCTGCCGATGCTGCGCGCGCTGGGGCGGTTCATC
GGCCGGGTGCTGTTCGTGCT

Product: lipid a biosynthesis acyltransferase

Products: NA

Alternate protein names: Lipid A Biosynthesis Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lipid A Biosynthesis Acyltransferase Family; Bacterial Lipid A Biosynthesis Acyltransferase; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Lipid A Biosynthesis Lauroyl Acyltransferase Protein; Acyltransferase Protein; Lauroyl Acyltransferase; Lipid A Lauroyl Acyltransferase Protein; Decanoyltransferase LpxX; Lauryl-Acyl Carrier Protein-Dependent Acyltransferase

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MSSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAGRMVAEAPRLWLRPEPPACEI
HGAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPEHGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVR
QMIKALRRGEAVGLLPDQVPPQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPT
LDAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA

Sequences:

>Translated_291_residues
MSSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAGRMVAEAPRLWLRPEPPACEI
HGAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPEHGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVR
QMIKALRRGEAVGLLPDQVPPQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPT
LDAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA
>Mature_290_residues
SSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAGRMVAEAPRLWLRPEPPACEIH
GAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPEHGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVRQ
MIKALRRGEAVGLLPDQVPPQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPTL
DAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787292, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082094, Length=216, Percent_Identity=25.462962962963, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.-

Molecular weight: Translated: 32274; Mature: 32143

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVAEAPRLWLRPEPPACEIHGAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPE
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
HGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVRQMIKALRRGEAVGLLPDQVP
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
PQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHCCCCCCHH
LDAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMVAEAPRLWLRPEPPACEIHGAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPE
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHCCCC
HGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVRQMIKALRRGEAVGLLPDQVP
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
PQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHCCCCCCHH
LDAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA