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The map label for this gene is pkn6 [H]

Identifier: 222109819

GI number: 222109819

Start: 623042

End: 624928

Strand: Direct

Name: pkn6 [H]

Synonym: Dtpsy_0603

Alternate gene names: 222109819

Gene position: 623042-624928 (Clockwise)

Preceding gene: 222109817

Following gene: 222109820

Centisome position: 16.41

GC content: 67.99

Gene sequence:

>1887_bases
ATGTCTTCGCTCCCCCCCCGCTTCACGCCCGCCAGCGTCGCGCACCACGTCGACGCCCTCCCGGCGGGCACCCGGTTGGG
AGAGTTCGAGATCGTGGCGCTGCTGGGCGTGGGTGGCTTCGGCATGGTGTACCAGGCGTTCGACCATTCCCTGCTGCGTT
TCGTCGCGATCAAGGAATACATGCCTGCCGCCTTGGCGGGCCGCGCGGACGGGCATTCGCTCTGGGTGCGTTCCTCGTCG
GACGAGCAGTCTTTCCAGGCGGGCCTGGCCTCGTTCGTGGACGAGGCGCGCCTGCTGGCGCAGTTCGACCATCCCTCGCT
GGTGAAGGTCTTCCGGTTCTGGGAAGCCAATCACACGGCCTACATGGTCATGCCCCTGTACAGCGGCTTGACCCTCAAGC
AGGCGCGTGCGCACATGCGCACGCCGCCCCCCGAGGAATGGCTGCGCAAGGTGTTGTGGTCGGTCACCAGCGCGTTGCGG
GTGCTGCACGAAGGACAGACGCTGCACCGCGACATCTCGCCGGACAACATCTTCCTGCAGGACCATGGCCCACCAGTGCT
GCTGGACCTCGGCGCCGCGCGGCATGCGATCAGCGACCGGGACCAGAAGCACACGGCCGTGCTCAAAGTCAACTACGCGC
CCATAGAGCAGTACACGGACGCGGCATCGCACCTGCACCAAGGGCCGTGGAGCGACCTGTATTCGCTGGGCGCCGTCGTG
CATGGCTGCCTGTGCAACGACACGCCGCTGCCCGCTACTCTGCGTGCCATACGTGACCGCATGGTGTCGTTCTCCCGCGT
AGCACGCACGGTGCGCAAGCAGTTCGGCGTGGAATACTCGCGTCCGTTCGTCGATGCGGTGTCGCAATGCCTGGCGCTGC
AGCCGCAAGACCGTCCGCAATCGATCGACGCGTTCCTGCAGACGATGGGCATGACGGCGGCGCCCGCGGGACTGGACGGG
TTCGACTTCCGTGCCGAACTGGGCTCCATCTGGGTGGAGCCCTCGAGCAAGGATGCGCAGGGCGTGGCAGTCCCGATGAT
CGACCTCACGGCGATGTCGCAGCCGCAGGATTCCCGGCCGCAGACCGCCACCGTTGTGGCGGCGCCGGCTAGCGCGCCTT
CAGACCTCATGGTGTCACCCGTGGAGCCTGCGACCGTGTTTGCGGAAACCGTTGCCGATGCGGGCGACACGCAGGCCTTC
GCAGATACGCGCGAGATGCCGCAACATGACGCGCCGACCGGTTCACGCCACCCGACGCACGCGCGCACACCCCGCCCCCA
GAAGGCTGCACGCCATGCATCAGCCCCCCGTGTTGCCACAGCAGGCCATGGCGGACGGGCGCGGCTGGTGTGGGGTATGG
CTGCCTCTCTGGCGCTGCTGGTCATCGCCAGCAGTCCGTGGTGGGGAGGCCGGGAGAACGCGCCGCGGTATACACCCGAA
AACGAGATCATCACGGAACTTGCGTCACCAGCGCCAGCACCGGAGCCGGCAGAGGTGGTGATGGTGTCGCATGAGGCGGC
GGACCCCGCGTCGGCGCCAATGGCAGTGCAGCAAGAGGCTGCGTCGGTGGCTGAGGCCCGGCCTGCGGTCGTTTCCAAAC
CCCGGCTTGTGCGCAAGGCTGCCGAGGCGACCGCGCCTGCCCCAGCGCCCGCCCCTGTGGTTCCGGCTCCGGAGCCAGCG
CCGCCTCCCCCTGCGCCGTCACGCCCTGCGGTGCCCGCAAGGGTGCCCGGGCCTGACGAGGCCTGCGAGGCATCCAGTTT
CTTTGCACGCCCCTTGTGCATTCACGAGCAATGCCAGAAGCCGGGGCTGGCCAACCATCCCGTTTGCGTGGAAAACCGCC
GCCGGCAGGAAGCCGAGGAGCGCAGGCGACAGCTTTACTCGCAGTAG

Upstream 100 bases:

>100_bases
CATCATGGCGTCCGCTGCGGCGTGCCGCGGCGCTTCCTCCGCTTCCTCGTTAGACTTCGCTGCCCTCGCTGATCCGCATC
CCTTGTCCGCAACGCCCTCC

Downstream 100 bases:

>100_bases
AGCACTGCGCAGCGGTCGATTTTGTATAATGGCCGGCTTCGCAGCGATTTTTAGGTCCCGCGGCGAAGCGCGACATCCCA
CCTAAGAGGCTTTCATCAGA

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MSSLPPRFTPASVAHHVDALPAGTRLGEFEIVALLGVGGFGMVYQAFDHSLLRFVAIKEYMPAALAGRADGHSLWVRSSS
DEQSFQAGLASFVDEARLLAQFDHPSLVKVFRFWEANHTAYMVMPLYSGLTLKQARAHMRTPPPEEWLRKVLWSVTSALR
VLHEGQTLHRDISPDNIFLQDHGPPVLLDLGAARHAISDRDQKHTAVLKVNYAPIEQYTDAASHLHQGPWSDLYSLGAVV
HGCLCNDTPLPATLRAIRDRMVSFSRVARTVRKQFGVEYSRPFVDAVSQCLALQPQDRPQSIDAFLQTMGMTAAPAGLDG
FDFRAELGSIWVEPSSKDAQGVAVPMIDLTAMSQPQDSRPQTATVVAAPASAPSDLMVSPVEPATVFAETVADAGDTQAF
ADTREMPQHDAPTGSRHPTHARTPRPQKAARHASAPRVATAGHGGRARLVWGMAASLALLVIASSPWWGGRENAPRYTPE
NEIITELASPAPAPEPAEVVMVSHEAADPASAPMAVQQEAASVAEARPAVVSKPRLVRKAAEATAPAPAPAPVVPAPEPA
PPPPAPSRPAVPARVPGPDEACEASSFFARPLCIHEQCQKPGLANHPVCVENRRRQEAEERRRQLYSQ

Sequences:

>Translated_628_residues
MSSLPPRFTPASVAHHVDALPAGTRLGEFEIVALLGVGGFGMVYQAFDHSLLRFVAIKEYMPAALAGRADGHSLWVRSSS
DEQSFQAGLASFVDEARLLAQFDHPSLVKVFRFWEANHTAYMVMPLYSGLTLKQARAHMRTPPPEEWLRKVLWSVTSALR
VLHEGQTLHRDISPDNIFLQDHGPPVLLDLGAARHAISDRDQKHTAVLKVNYAPIEQYTDAASHLHQGPWSDLYSLGAVV
HGCLCNDTPLPATLRAIRDRMVSFSRVARTVRKQFGVEYSRPFVDAVSQCLALQPQDRPQSIDAFLQTMGMTAAPAGLDG
FDFRAELGSIWVEPSSKDAQGVAVPMIDLTAMSQPQDSRPQTATVVAAPASAPSDLMVSPVEPATVFAETVADAGDTQAF
ADTREMPQHDAPTGSRHPTHARTPRPQKAARHASAPRVATAGHGGRARLVWGMAASLALLVIASSPWWGGRENAPRYTPE
NEIITELASPAPAPEPAEVVMVSHEAADPASAPMAVQQEAASVAEARPAVVSKPRLVRKAAEATAPAPAPAPVVPAPEPA
PPPPAPSRPAVPARVPGPDEACEASSFFARPLCIHEQCQKPGLANHPVCVENRRRQEAEERRRQLYSQ
>Mature_627_residues
SSLPPRFTPASVAHHVDALPAGTRLGEFEIVALLGVGGFGMVYQAFDHSLLRFVAIKEYMPAALAGRADGHSLWVRSSSD
EQSFQAGLASFVDEARLLAQFDHPSLVKVFRFWEANHTAYMVMPLYSGLTLKQARAHMRTPPPEEWLRKVLWSVTSALRV
LHEGQTLHRDISPDNIFLQDHGPPVLLDLGAARHAISDRDQKHTAVLKVNYAPIEQYTDAASHLHQGPWSDLYSLGAVVH
GCLCNDTPLPATLRAIRDRMVSFSRVARTVRKQFGVEYSRPFVDAVSQCLALQPQDRPQSIDAFLQTMGMTAAPAGLDGF
DFRAELGSIWVEPSSKDAQGVAVPMIDLTAMSQPQDSRPQTATVVAAPASAPSDLMVSPVEPATVFAETVADAGDTQAFA
DTREMPQHDAPTGSRHPTHARTPRPQKAARHASAPRVATAGHGGRARLVWGMAASLALLVIASSPWWGGRENAPRYTPEN
EIITELASPAPAPEPAEVVMVSHEAADPASAPMAVQQEAASVAEARPAVVSKPRLVRKAAEATAPAPAPAPVVPAPEPAP
PPPAPSRPAVPARVPGPDEACEASSFFARPLCIHEQCQKPGLANHPVCVENRRRQEAEERRRQLYSQ

Specific function: Pkn5 and pkn6 may have reciprocal roles in growth and development. Pkn6 may be a transmembrane sensor of external signals for development [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI261244929, Length=296, Percent_Identity=25.3378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI222418622, Length=296, Percent_Identity=25.3378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI261244925, Length=296, Percent_Identity=25.3378378378378, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI207029299, Length=178, Percent_Identity=30.3370786516854, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI261244921, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI261244927, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI261244923, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI19923407, Length=296, Percent_Identity=25.3378378378378, Blast_Score=74, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86562808, Length=230, Percent_Identity=26.9565217391304, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321126, Length=276, Percent_Identity=25.3623188405797, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320685, Length=246, Percent_Identity=24.7967479674797, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6324557, Length=276, Percent_Identity=25.3623188405797, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324927, Length=179, Percent_Identity=29.608938547486, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR013229
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF08308 PEGA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 67770; Mature: 67639

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLPPRFTPASVAHHVDALPAGTRLGEFEIVALLGVGGFGMVYQAFDHSLLRFVAIKEY
CCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
MPAALAGRADGHSLWVRSSSDEQSFQAGLASFVDEARLLAQFDHPSLVKVFRFWEANHTA
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCE
YMVMPLYSGLTLKQARAHMRTPPPEEWLRKVLWSVTSALRVLHEGQTLHRDISPDNIFLQ
EEEEEHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEE
DHGPPVLLDLGAARHAISDRDQKHTAVLKVNYAPIEQYTDAASHLHQGPWSDLYSLGAVV
CCCCEEEEECCHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
HGCLCNDTPLPATLRAIRDRMVSFSRVARTVRKQFGVEYSRPFVDAVSQCLALQPQDRPQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH
SIDAFLQTMGMTAAPAGLDGFDFRAELGSIWVEPSSKDAQGVAVPMIDLTAMSQPQDSRP
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCCC
QTATVVAAPASAPSDLMVSPVEPATVFAETVADAGDTQAFADTREMPQHDAPTGSRHPTH
CEEEEEECCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCC
ARTPRPQKAARHASAPRVATAGHGGRARLVWGMAASLALLVIASSPWWGGRENAPRYTPE
CCCCCHHHHHHHCCCCCEEECCCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC
NEIITELASPAPAPEPAEVVMVSHEAADPASAPMAVQQEAASVAEARPAVVSKPRLVRKA
HHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHH
AEATAPAPAPAPVVPAPEPAPPPPAPSRPAVPARVPGPDEACEASSFFARPLCIHEQCQK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
PGLANHPVCVENRRRQEAEERRRQLYSQ
CCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSLPPRFTPASVAHHVDALPAGTRLGEFEIVALLGVGGFGMVYQAFDHSLLRFVAIKEY
CCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
MPAALAGRADGHSLWVRSSSDEQSFQAGLASFVDEARLLAQFDHPSLVKVFRFWEANHTA
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCE
YMVMPLYSGLTLKQARAHMRTPPPEEWLRKVLWSVTSALRVLHEGQTLHRDISPDNIFLQ
EEEEEHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEE
DHGPPVLLDLGAARHAISDRDQKHTAVLKVNYAPIEQYTDAASHLHQGPWSDLYSLGAVV
CCCCEEEEECCHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHH
HGCLCNDTPLPATLRAIRDRMVSFSRVARTVRKQFGVEYSRPFVDAVSQCLALQPQDRPQ
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHH
SIDAFLQTMGMTAAPAGLDGFDFRAELGSIWVEPSSKDAQGVAVPMIDLTAMSQPQDSRP
HHHHHHHHHCCCCCCCCCCCCHHHHHHCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCCC
QTATVVAAPASAPSDLMVSPVEPATVFAETVADAGDTQAFADTREMPQHDAPTGSRHPTH
CEEEEEECCCCCCCCCEECCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCC
ARTPRPQKAARHASAPRVATAGHGGRARLVWGMAASLALLVIASSPWWGGRENAPRYTPE
CCCCCHHHHHHHCCCCCEEECCCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCC
NEIITELASPAPAPEPAEVVMVSHEAADPASAPMAVQQEAASVAEARPAVVSKPRLVRKA
HHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCHHHHHH
AEATAPAPAPAPVVPAPEPAPPPPAPSRPAVPARVPGPDEACEASSFFARPLCIHEQCQK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHCC
PGLANHPVCVENRRRQEAEERRRQLYSQ
CCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8733241 [H]