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The map label for this gene is dtd [H]

Identifier: 222109706

GI number: 222109706

Start: 504356

End: 504817

Strand: Direct

Name: dtd [H]

Synonym: Dtpsy_0488

Alternate gene names: 222109706

Gene position: 504356-504817 (Clockwise)

Preceding gene: 222109705

Following gene: 222109707

Centisome position: 13.28

GC content: 71.43

Gene sequence:

>462_bases
ATGATCGGCCTGCTGCAGCGCGTGCGCGAGGCGCGCGTGGAAGTGGCCGGCGAGATCGTGGGCCGCATCGGCCCGGGGCT
GCTGGCGCTGGTGTGCGCCGAGCAGGGCGACAGCGAGGCGCAGGCCGACAAGCTGCTGGCCAAAATGCTCAAGCTGCGCA
TCTTCAGCGACGAGGCCGGAAAGATGAACCGCAGCGTGCAGGACCTGGACGGGCAGGGCACCTGCGGCGGCCTGCTCATC
GTCAGCCAGTTCACCCTGGCCGCCGACACGCGCGGCGGCAACCGGCCCAGCTTCACGCAGGCGGCACCGCCGGCGCAGGG
GGAGCGGCTGTACGACTACTTCGTCGCCCAGGCGCGCGCCGTGCACCCCATGGTGGCCACGGGCCGCTTTGCCGCCGACA
TGCAGGTGCACCTGGTCAACGACGGGCCGGTGACCCTTCCGCTGCGGATAGCGCCGGGATAA

Upstream 100 bases:

>100_bases
AGGCCGTGCCCGGCCTGCGCGCCACCATCGAACTGCTGCCCGAAGGGCAGGCTACGGTGTTCGAGACCGCCGAGGCGGCC
GCGCCGGGAGGAGCCGGCAC

Downstream 100 bases:

>100_bases
TTGGCGACCATGACTATCTCTTCAGGCGCGTCGCCTGCCCCGTCCGCCACCGCCTTCTCATCGCTGCCTCTGTCCCCTGA
AATGCTGGCCAACCTGCAGC

Product: d-tyrosyl-tRNA(tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAGKMNRSVQDLDGQGTCGGLLI
VSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARAVHPMVATGRFAADMQVHLVNDGPVTLPLRIAPG

Sequences:

>Translated_153_residues
MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAGKMNRSVQDLDGQGTCGGLLI
VSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARAVHPMVATGRFAADMQVHLVNDGPVTLPLRIAPG
>Mature_153_residues
MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAGKMNRSVQDLDGQGTCGGLLI
VSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARAVHPMVATGRFAADMQVHLVNDGPVTLPLRIAPG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=157, Percent_Identity=39.4904458598726, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1790320, Length=150, Percent_Identity=54, Blast_Score=154, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=37.8378378378378, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319982, Length=147, Percent_Identity=37.4149659863946, Blast_Score=88, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281361569, Length=150, Percent_Identity=38.6666666666667, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16269; Mature: 16269

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAG
CCHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
KMNRSVQDLDGQGTCGGLLIVSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARA
HHCCCHHCCCCCCCCCCEEEEHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VHPMVATGRFAADMQVHLVNDGPVTLPLRIAPG
CCCHHHCCCEECCEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MIGLLQRVREARVEVAGEIVGRIGPGLLALVCAEQGDSEAQADKLLAKMLKLRIFSDEAG
CCHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCC
KMNRSVQDLDGQGTCGGLLIVSQFTLAADTRGGNRPSFTQAAPPAQGERLYDYFVAQARA
HHCCCHHCCCCCCCCCCEEEEHHHHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VHPMVATGRFAADMQVHLVNDGPVTLPLRIAPG
CCCHHHCCCEECCEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA