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The map label for this gene is glpD2 [H]

Identifier: 222109602

GI number: 222109602

Start: 394369

End: 395967

Strand: Direct

Name: glpD2 [H]

Synonym: Dtpsy_0382

Alternate gene names: 222109602

Gene position: 394369-395967 (Clockwise)

Preceding gene: 222109601

Following gene: 222109603

Centisome position: 10.39

GC content: 69.79

Gene sequence:

>1599_bases
ATGACTAGCGACACCTCCACCCCTTTGGCAACCGTACGGGCCGACCTGTTGGCCCGCCTGGCTCAACCCGTGACCTACGA
CCTGGCGGTCGTCGGAGGTGGGGCGACGGGCCTGGGGGTGGCGCTGGATGCGGCGGCGCGCGGCTTTTCCGTCGTGCTGC
TGGAATCGCACGACTTCGCCAAGGGCACCTCCTCGCGTGCCACCAAGCTGGTGCACGGCGGCGTGCGCTACCTCGCGCAG
GGCAACATCGCCCTGGTGCGCGAGGCGCTGCACGAGCGCACCACGCTGTTGCGCAACGCCCCCCATCTGGCGCAGCCGTT
GGCATTCGTCATGCCTTCTTACAAGGTGTGGGAAACGCCGTTCTACGGTGTGGGCCTGAAGATGTACGACGCCCTGGCCG
GCAAGGCGGGCCTGGGGCCTACCGAATTCCTTGGGCGCATGGAAACCCTGCGCTGCCTGCCCACGGCCATGGCCGACGGG
CTCAAGGGCGGCGTGAAGTATTGGGACGGGCAGTTCGACGACGCCCGACTGGCCCTGGCCCTGGCGCGTACCGCCGCGCA
GCGGGGGGCTCTGCTGCTCAACTACTGCCCCGTGGATGACCTGTTGTACGACGGGGGGAAGGTGGCGGGCGTGGTTTGCC
AGGATGCCGAGACCGGGCAGCGCTACGAGGTGCGCGCGCGCTGCGTGGTCAACGCCACCGGCGTGTGGGTGGACGCCCTG
CGCCAGCGCGATGGCGATGTGAGCGGCCAGCCCGCCAAGCCCATGGTGGCGCCCAGCCAGGGGGTGCATATCGTGGTGGA
CCGCGAGTTCTTGCCCTCCGACCATGCGCTGATGGTGCCCAAGACGGCCGACGGGCGGGTGCTGTTTGCGGTGCCCTGGC
TGGGCAAGGTGATTTTGGGCACGACCGACAGCCCACGCCAGGATCTGGCGCGCGAGCCCCAGGCCATGCGGGAGGAAGTG
GCCTTCATCCTGGGGGAATCGGCGCGCTACCTGCGGCGCGCCCCCCAGGCTAGCGATGTGCGCAGCATCTGGGTGGGCCT
GCGTCCCTTGGTCAAGCCCTCGGACGAAGACGCCGCCGCCACCAAGAGCATCAGCCGGGAACACACCGTGCTGGCCAGCC
GCAGCGGGCTGGTCACCGTGACTGGCGGCAAGTGGACCACCTACCGCGCCATGGCCGAGGATGTACTGCTCAAGTGCATG
GACGAACACCTGCTGCCGCGCCGCCCGGGCGGGATCACCGTTGCGCTGCCCCTGGTAGGAGCCGGTGCCACCCGGGAGCG
CCAGGGAATGAACGCGCCCCAGGGGCTGCATTCCTACGGTGACGAGGCCGCGCGGGTGCAAGCCCTTCCGGGTTCGCAGG
TGCAACTGGCCGAAGGGCTCAGCGAGGCCATGGTGCGCTTTGCCGCGCGCCATGAGTACGCACGCACCGTGGAGGACGTG
CTCGCACGGCGCTCGCGCGTGCTGTTTCTCGATGCGCGCCTGGCGGCCGCGCTGGCGCCGCGCGTGGCGGACATCCTGCG
CGAGGAAATCCCCGGCCAGGACCCGCAGCTGCCCGCGTTCCTGGAGTTGGCCGCACACTACGCCACGGTGCCGGTATAA

Upstream 100 bases:

>100_bases
GCCGCAGCGGATGGGCCCTTTGCCGGGCCCATCCCGCGGATCCGGTCACAATTCAGGGTAAACCCTGATTTTTCTGCCAG
GGTTACGGACCATTCCCCTT

Downstream 100 bases:

>100_bases
AAAGCGCTTGACGCCCGGTTTTAAGTTTGCGATACTACCGGGCTTCGCGTTAAGTGCGCGAGGTTTCTGCCCAGCGGGAA
GCGCCGCAAATGGTTTGCGG

Product: fad dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 531

Protein sequence:

>532_residues
MTSDTSTPLATVRADLLARLAQPVTYDLAVVGGGATGLGVALDAAARGFSVVLLESHDFAKGTSSRATKLVHGGVRYLAQ
GNIALVREALHERTTLLRNAPHLAQPLAFVMPSYKVWETPFYGVGLKMYDALAGKAGLGPTEFLGRMETLRCLPTAMADG
LKGGVKYWDGQFDDARLALALARTAAQRGALLLNYCPVDDLLYDGGKVAGVVCQDAETGQRYEVRARCVVNATGVWVDAL
RQRDGDVSGQPAKPMVAPSQGVHIVVDREFLPSDHALMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLAREPQAMREEV
AFILGESARYLRRAPQASDVRSIWVGLRPLVKPSDEDAAATKSISREHTVLASRSGLVTVTGGKWTTYRAMAEDVLLKCM
DEHLLPRRPGGITVALPLVGAGATRERQGMNAPQGLHSYGDEAARVQALPGSQVQLAEGLSEAMVRFAARHEYARTVEDV
LARRSRVLFLDARLAAALAPRVADILREEIPGQDPQLPAFLELAAHYATVPV

Sequences:

>Translated_532_residues
MTSDTSTPLATVRADLLARLAQPVTYDLAVVGGGATGLGVALDAAARGFSVVLLESHDFAKGTSSRATKLVHGGVRYLAQ
GNIALVREALHERTTLLRNAPHLAQPLAFVMPSYKVWETPFYGVGLKMYDALAGKAGLGPTEFLGRMETLRCLPTAMADG
LKGGVKYWDGQFDDARLALALARTAAQRGALLLNYCPVDDLLYDGGKVAGVVCQDAETGQRYEVRARCVVNATGVWVDAL
RQRDGDVSGQPAKPMVAPSQGVHIVVDREFLPSDHALMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLAREPQAMREEV
AFILGESARYLRRAPQASDVRSIWVGLRPLVKPSDEDAAATKSISREHTVLASRSGLVTVTGGKWTTYRAMAEDVLLKCM
DEHLLPRRPGGITVALPLVGAGATRERQGMNAPQGLHSYGDEAARVQALPGSQVQLAEGLSEAMVRFAARHEYARTVEDV
LARRSRVLFLDARLAAALAPRVADILREEIPGQDPQLPAFLELAAHYATVPV
>Mature_531_residues
TSDTSTPLATVRADLLARLAQPVTYDLAVVGGGATGLGVALDAAARGFSVVLLESHDFAKGTSSRATKLVHGGVRYLAQG
NIALVREALHERTTLLRNAPHLAQPLAFVMPSYKVWETPFYGVGLKMYDALAGKAGLGPTEFLGRMETLRCLPTAMADGL
KGGVKYWDGQFDDARLALALARTAAQRGALLLNYCPVDDLLYDGGKVAGVVCQDAETGQRYEVRARCVVNATGVWVDALR
QRDGDVSGQPAKPMVAPSQGVHIVVDREFLPSDHALMVPKTADGRVLFAVPWLGKVILGTTDSPRQDLAREPQAMREEVA
FILGESARYLRRAPQASDVRSIWVGLRPLVKPSDEDAAATKSISREHTVLASRSGLVTVTGGKWTTYRAMAEDVLLKCMD
EHLLPRRPGGITVALPLVGAGATRERQGMNAPQGLHSYGDEAARVQALPGSQVQLAEGLSEAMVRFAARHEYARTVEDVL
ARRSRVLFLDARLAAALAPRVADILREEIPGQDPQLPAFLELAAHYATVPV

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=547, Percent_Identity=39.853747714808, Blast_Score=359, Evalue=4e-99,
Organism=Homo sapiens, GI285002231, Length=547, Percent_Identity=39.853747714808, Blast_Score=359, Evalue=4e-99,
Organism=Escherichia coli, GI2367226, Length=467, Percent_Identity=29.9785867237687, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788574, Length=363, Percent_Identity=30.5785123966942, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17509253, Length=545, Percent_Identity=39.8165137614679, Blast_Score=334, Evalue=8e-92,
Organism=Caenorhabditis elegans, GI115534726, Length=529, Percent_Identity=35.9168241965974, Blast_Score=308, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6322036, Length=597, Percent_Identity=34.8408710217755, Blast_Score=314, Evalue=2e-86,
Organism=Drosophila melanogaster, GI161077125, Length=536, Percent_Identity=38.8059701492537, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24653942, Length=536, Percent_Identity=38.8059701492537, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24653944, Length=536, Percent_Identity=38.8059701492537, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI20130025, Length=536, Percent_Identity=38.8059701492537, Blast_Score=328, Evalue=6e-90,
Organism=Drosophila melanogaster, GI24586295, Length=566, Percent_Identity=31.6254416961131, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI19921278, Length=505, Percent_Identity=28.7128712871287, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI45550977, Length=388, Percent_Identity=27.5773195876289, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 57187; Mature: 57056

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDTSTPLATVRADLLARLAQPVTYDLAVVGGGATGLGVALDAAARGFSVVLLESHDFA
CCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCC
KGTSSRATKLVHGGVRYLAQGNIALVREALHERTTLLRNAPHLAQPLAFVMPSYKVWETP
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCC
FYGVGLKMYDALAGKAGLGPTEFLGRMETLRCLPTAMADGLKGGVKYWDGQFDDARLALA
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHH
LARTAAQRGALLLNYCPVDDLLYDGGKVAGVVCQDAETGQRYEVRARCVVNATGVWVDAL
HHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHH
RQRDGDVSGQPAKPMVAPSQGVHIVVDREFLPSDHALMVPKTADGRVLFAVPWLGKVILG
HHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEC
TTDSPRQDLAREPQAMREEVAFILGESARYLRRAPQASDVRSIWVGLRPLVKPSDEDAAA
CCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHH
TKSISREHTVLASRSGLVTVTGGKWTTYRAMAEDVLLKCMDEHLLPRRPGGITVALPLVG
HHHHCHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
AGATRERQGMNAPQGLHSYGDEAARVQALPGSQVQLAEGLSEAMVRFAARHEYARTVEDV
CCCCHHHCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARRSRVLFLDARLAAALAPRVADILREEIPGQDPQLPAFLELAAHYATVPV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSDTSTPLATVRADLLARLAQPVTYDLAVVGGGATGLGVALDAAARGFSVVLLESHDFA
CCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCC
KGTSSRATKLVHGGVRYLAQGNIALVREALHERTTLLRNAPHLAQPLAFVMPSYKVWETP
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCC
FYGVGLKMYDALAGKAGLGPTEFLGRMETLRCLPTAMADGLKGGVKYWDGQFDDARLALA
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHH
LARTAAQRGALLLNYCPVDDLLYDGGKVAGVVCQDAETGQRYEVRARCVVNATGVWVDAL
HHHHHHHCCCEEEEECCHHHHHHCCCCEEEEEECCCCCCCCEEEEEEEEEECCHHHHHHH
RQRDGDVSGQPAKPMVAPSQGVHIVVDREFLPSDHALMVPKTADGRVLFAVPWLGKVILG
HHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCEEEEC
TTDSPRQDLAREPQAMREEVAFILGESARYLRRAPQASDVRSIWVGLRPLVKPSDEDAAA
CCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHH
TKSISREHTVLASRSGLVTVTGGKWTTYRAMAEDVLLKCMDEHLLPRRPGGITVALPLVG
HHHHCHHHHEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
AGATRERQGMNAPQGLHSYGDEAARVQALPGSQVQLAEGLSEAMVRFAARHEYARTVEDV
CCCCHHHCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARRSRVLFLDARLAAALAPRVADILREEIPGQDPQLPAFLELAAHYATVPV
HHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]