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The map label for this gene is argS

Identifier: 222109552

GI number: 222109552

Start: 341331

End: 343034

Strand: Direct

Name: argS

Synonym: Dtpsy_0332

Alternate gene names: 222109552

Gene position: 341331-343034 (Clockwise)

Preceding gene: 222109550

Following gene: 222109553

Centisome position: 8.99

GC content: 65.9

Gene sequence:

>1704_bases
ATGCTCTCCGTCAAACAGGAATTGCTCGCGGCGCTGGCCGACGAGCTGGAAAAGGTGTCGCCCGGCGCAGGCAGCCGCGC
GGCCTTCGAATCTCCCAAGGTCGCTGCCCATGGCGACCTCGCGTGCACGGCCGCCATGCAGCTGGCCAAGCCCCTCAAGC
AGAATCCCCGCGCACTGGGCGAACAGCTACAGGCCGCGCTGGAGGCCACGCCCGCGTTCCAAAAATGGGTGCAAGCCATC
GAGATCGCCGGCCCCGGTTTTCTGAACATCCGCCTCAAGCCCGCCGCCAAGCAGCAGGTGGTGCGCGAGGTGCTGGCGCA
AGGCGCGCAATATGGCTACCAGCCGGCGCGCGGCGAGAAAGTCCTGGTGGAGTTCGTCTCCGCCAACCCCACCGGCCCGC
TGCACGTCGGTCACGGCCGCCAGGCCGCCATCGGCGACGCCATCAGCCATCTGTACGCCACCCAGGGCTGGAGCGTGCAC
CGCGAGTTCTATTACAACGACGCGGGCGTGCAGATCGACACGCTCACCAAGAGCACGCAACTGCGCGCCAAGGGCTTCAA
GCCCGGCGACGACTGCTGGCCCACGGACAGCGAGAACCCGCTGGCCAAGAATTTCTACAACGGCGATTACATCCAGGACA
TCGCCGACGCCTTCCTCGCCAAGGCCACCGTCCAGGCCGATGACCGCGCGTTCACGGCCAATGGCGATGTCGAGGATTAC
GAGAACATCCGCCAGTTCGCCGTGGCCTACCTGCGCAACGAGCAGGACAAGGATCTGCAGGCCTTCAACCTCCAGTTCGA
CCAGTACTACCTGGAGTCCAGCCTCTACGCCAACGGCCATGTGGACGCTACCGTGCAGCGCCTCGTCGCCAACGGCAAAA
CCTACGAGCAGGACGGCGCGCTGTGGCTCAAATCCACCGACTACGGGGACGACAAGGACCGCGTCATGCGCAAGCAGGAC
GGCACGTACACCTACTTCGTGCCTGATGTGGCCTACCACATCCAGAAGTTCCAGCGCGGCTTCACCAAGGTGGTGAACAT
CCAGGGCACGGACCACCACGGCACCATCGCGCGCGTGCGCGCCGGCCTGCAGGCGGCGGACGTGGGCATCCCCCAGGGCT
ACCCCGACTACGTGCTGCACACCATGGTGCGCGTGGTGCGCAATGGCGAGGAGGTCAAGATCAGCAAGCGCGCCGGCAGC
TACGTGACGCTGCGCGACCTGATCGAGTGGACCAGCAAGGACGCGGTGCGTTTCTTCCTGCTGTCGCGCAAGCCCGACAC
CGAATACACCTTCGACGTCGACCTGGCCGTGGCGCAGAACAACGACAACCCCGTGTATTACGTGCAGTACGCCCATGCGC
GCATCTGCTCGGTGCTGCGCGGCTGGCGCGAGGACTACGACGTGGCCGCGCTGCGCGATGTGGACCTGTCGCCGCTGGAA
GGCCCGCAGGCCCAGGCGCTGATGCTGCTGCTCGCCAAGTATCCCGAGATGCTCACCGCAGCCGCGGCCGGCAATGCGCC
GCACGACGTGACCTTCTACCTGCGCGACCTGGCCGCCGCCTACCACAGCTATTACGACGCCGAACGCATTCTGGTGGACG
ACGAGGCCGTCAAGCAGGCGCGGCTGGCGCTCGTCGCGGCCACAGCGCAGGTATTGCACAATGGATTGGCGGTGCTGGGC
GTGTCTGCGCCAGCCAGAATGTAA

Upstream 100 bases:

>100_bases
GGTGAATGCGCCCGTCGGCAACGCAGTGCCCCACGGGCCACCCAGCATAACGCCGGGCGGTCACGAATGGATGACGGGTC
GGCCCGTAGAATCCGCCCCC

Downstream 100 bases:

>100_bases
GTGACCACTGATATGAAGAAACAGCAACGCGGCGGCACCATCGTGGGCTTCATCCTCGGGGTGATCGTGGGCCTGGGAGC
CGCGCTGGCCGTGGCCGTGT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MLSVKQELLAALADELEKVSPGAGSRAAFESPKVAAHGDLACTAAMQLAKPLKQNPRALGEQLQAALEATPAFQKWVQAI
EIAGPGFLNIRLKPAAKQQVVREVLAQGAQYGYQPARGEKVLVEFVSANPTGPLHVGHGRQAAIGDAISHLYATQGWSVH
REFYYNDAGVQIDTLTKSTQLRAKGFKPGDDCWPTDSENPLAKNFYNGDYIQDIADAFLAKATVQADDRAFTANGDVEDY
ENIRQFAVAYLRNEQDKDLQAFNLQFDQYYLESSLYANGHVDATVQRLVANGKTYEQDGALWLKSTDYGDDKDRVMRKQD
GTYTYFVPDVAYHIQKFQRGFTKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVRNGEEVKISKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLRGWREDYDVAALRDVDLSPLE
GPQAQALMLLLAKYPEMLTAAAAGNAPHDVTFYLRDLAAAYHSYYDAERILVDDEAVKQARLALVAATAQVLHNGLAVLG
VSAPARM

Sequences:

>Translated_567_residues
MLSVKQELLAALADELEKVSPGAGSRAAFESPKVAAHGDLACTAAMQLAKPLKQNPRALGEQLQAALEATPAFQKWVQAI
EIAGPGFLNIRLKPAAKQQVVREVLAQGAQYGYQPARGEKVLVEFVSANPTGPLHVGHGRQAAIGDAISHLYATQGWSVH
REFYYNDAGVQIDTLTKSTQLRAKGFKPGDDCWPTDSENPLAKNFYNGDYIQDIADAFLAKATVQADDRAFTANGDVEDY
ENIRQFAVAYLRNEQDKDLQAFNLQFDQYYLESSLYANGHVDATVQRLVANGKTYEQDGALWLKSTDYGDDKDRVMRKQD
GTYTYFVPDVAYHIQKFQRGFTKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVRNGEEVKISKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLRGWREDYDVAALRDVDLSPLE
GPQAQALMLLLAKYPEMLTAAAAGNAPHDVTFYLRDLAAAYHSYYDAERILVDDEAVKQARLALVAATAQVLHNGLAVLG
VSAPARM
>Mature_567_residues
MLSVKQELLAALADELEKVSPGAGSRAAFESPKVAAHGDLACTAAMQLAKPLKQNPRALGEQLQAALEATPAFQKWVQAI
EIAGPGFLNIRLKPAAKQQVVREVLAQGAQYGYQPARGEKVLVEFVSANPTGPLHVGHGRQAAIGDAISHLYATQGWSVH
REFYYNDAGVQIDTLTKSTQLRAKGFKPGDDCWPTDSENPLAKNFYNGDYIQDIADAFLAKATVQADDRAFTANGDVEDY
ENIRQFAVAYLRNEQDKDLQAFNLQFDQYYLESSLYANGHVDATVQRLVANGKTYEQDGALWLKSTDYGDDKDRVMRKQD
GTYTYFVPDVAYHIQKFQRGFTKVVNIQGTDHHGTIARVRAGLQAADVGIPQGYPDYVLHTMVRVVRNGEEVKISKRAGS
YVTLRDLIEWTSKDAVRFFLLSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLRGWREDYDVAALRDVDLSPLE
GPQAQALMLLLAKYPEMLTAAAAGNAPHDVTFYLRDLAAAYHSYYDAERILVDDEAVKQARLALVAATAQVLHNGLAVLG
VSAPARM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=23.8333333333333, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI1788184, Length=603, Percent_Identity=27.1973466003317, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71985061, Length=603, Percent_Identity=22.0563847429519, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71985068, Length=568, Percent_Identity=21.6549295774648, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320548, Length=598, Percent_Identity=25.5852842809365, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6321883, Length=512, Percent_Identity=27.34375, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_ACIET (B9MBD2)

Other databases:

- EMBL:   CP001392
- RefSeq:   YP_002551816.1
- ProteinModelPortal:   B9MBD2
- GeneID:   7385340
- GenomeReviews:   CP001392_GR
- KEGG:   dia:Dtpsy_0332
- ProtClustDB:   PRK01611
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62703; Mature: 62703

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSVKQELLAALADELEKVSPGAGSRAAFESPKVAAHGDLACTAAMQLAKPLKQNPRALG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
EQLQAALEATPAFQKWVQAIEIAGPGFLNIRLKPAAKQQVVREVLAQGAQYGYQPARGEK
HHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCE
VLVEFVSANPTGPLHVGHGRQAAIGDAISHLYATQGWSVHREFYYNDAGVQIDTLTKSTQ
EEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCHH
LRAKGFKPGDDCWPTDSENPLAKNFYNGDYIQDIADAFLAKATVQADDRAFTANGDVEDY
HHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHH
ENIRQFAVAYLRNEQDKDLQAFNLQFDQYYLESSLYANGHVDATVQRLVANGKTYEQDGA
HHHHHHHHHHHHCCCCCCCHHEECHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
LWLKSTDYGDDKDRVMRKQDGTYTYFVPDVAYHIQKFQRGFTKVVNIQGTDHHGTIARVR
EEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
AGLQAADVGIPQGYPDYVLHTMVRVVRNGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFL
HCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHCCCHHEEEEE
LSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLRGWREDYDVAALRDVDLSPLE
EECCCCCCEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
GPQAQALMLLLAKYPEMLTAAAAGNAPHDVTFYLRDLAAAYHSYYDAERILVDDEAVKQA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
RLALVAATAQVLHNGLAVLGVSAPARM
HHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure
MLSVKQELLAALADELEKVSPGAGSRAAFESPKVAAHGDLACTAAMQLAKPLKQNPRALG
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
EQLQAALEATPAFQKWVQAIEIAGPGFLNIRLKPAAKQQVVREVLAQGAQYGYQPARGEK
HHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCE
VLVEFVSANPTGPLHVGHGRQAAIGDAISHLYATQGWSVHREFYYNDAGVQIDTLTKSTQ
EEEEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCHH
LRAKGFKPGDDCWPTDSENPLAKNFYNGDYIQDIADAFLAKATVQADDRAFTANGDVEDY
HHCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHH
ENIRQFAVAYLRNEQDKDLQAFNLQFDQYYLESSLYANGHVDATVQRLVANGKTYEQDGA
HHHHHHHHHHHHCCCCCCCHHEECHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
LWLKSTDYGDDKDRVMRKQDGTYTYFVPDVAYHIQKFQRGFTKVVNIQGTDHHGTIARVR
EEEEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHH
AGLQAADVGIPQGYPDYVLHTMVRVVRNGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFL
HCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHCCCHHEEEEE
LSRKPDTEYTFDVDLAVAQNNDNPVYYVQYAHARICSVLRGWREDYDVAALRDVDLSPLE
EECCCCCCEEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
GPQAQALMLLLAKYPEMLTAAAAGNAPHDVTFYLRDLAAAYHSYYDAERILVDDEAVKQA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
RLALVAATAQVLHNGLAVLGVSAPARM
HHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA