| Definition | Acidovorax ebreus TPSY chromosome, complete genome. |
|---|---|
| Accession | NC_011992 |
| Length | 3,796,573 |
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The map label for this gene is livF [H]
Identifier: 222109396
GI number: 222109396
Start: 197101
End: 197880
Strand: Direct
Name: livF [H]
Synonym: Dtpsy_0175
Alternate gene names: 222109396
Gene position: 197101-197880 (Clockwise)
Preceding gene: 222109395
Following gene: 222109398
Centisome position: 5.19
GC content: 71.41
Gene sequence:
>780_bases ATGAACAATCAAAACGATAGCGCCTCGCGCTTGCCAGACAAGGCTTTGGTGGCAAAAACACCTTTGCTGGAGGTGGCGGA CCTGCACGCCTGGTATGGCGCCGCCCACATCCTGCACGGCGTATCGCTGAGCGTGGGGCACGGCGAGGTGGTGGCCCTGA TGGGGCGCAACGGCGCGGGCAAGTCCACCACGCTCAAGGGCATTGCCGGCCTGATGGAGCGGCGCAGCGGGCGCATCGAG TTCCTGGGCCAGCGCATCGACCGCCAGCCGCCGCACGCCATCGCGCGGCGCGGCCTGGGCTACGTGCCGGAGGACCGGCG CATCTTCACCGACCTCACGGTGCTGGAGAACCTGGAGGTGGGCCGCCAAAGGCCCCGCCACTGGCCGGACGGCACGCCCG CGCCGCTGTGGACGCCCGAGCGGCTGTTCACGCTGTTCCCCAACCTGGGCGAAATGCCCGACCGCCCCGGCGGGCGCATG AGCGGCGGCGAGCAGCAGATGCTGACCGTGGCGCGCACCCTCATGGGCCAGCCGCTGCTGGTGCTGCTGGACGAGCCCTC GGAGGGCGTGGCGCCGGTCATCGTGCAGCAGATGGCGCGCACCATCCGCGCGCTGAAGGCCCAGGGCATCGGCATCCTGC TGAGCGAGCAGAACCTGCCCTTCGCCGAGGCCGTGGCCGACCGCGCCTGCGTGCTGGAGCAGGGCCGCATCGTGTACAGC GCGGGGATGGCGCAGCTGGCGGGCGACGCCGCGGCGCGGCGGCAGTACCTGGGCGTCTAG
Upstream 100 bases:
>100_bases TGCTGGTGCGCGGCCAGCTGCTGGCCGAGGGCACGCCGCAGCAGATCCAGGACGACGCGCGGGTGCAGGCCGCCTACCTG GGCACGGAGCTGGAGTCGGC
Downstream 100 bases:
>100_bases CGGCCCAGGGACACGTGGGGGCCAGGCCGTTCAGGCGGCGGCCACCTGCGCCAGATGCTCCGCCACCACCTGCGCCAGCC AGTCCATCACCGTGCGCACA
Product: ABC transporter
Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein F [H]
Number of amino acids: Translated: 259; Mature: 259
Protein sequence:
>259_residues MNNQNDSASRLPDKALVAKTPLLEVADLHAWYGAAHILHGVSLSVGHGEVVALMGRNGAGKSTTLKGIAGLMERRSGRIE FLGQRIDRQPPHAIARRGLGYVPEDRRIFTDLTVLENLEVGRQRPRHWPDGTPAPLWTPERLFTLFPNLGEMPDRPGGRM SGGEQQMLTVARTLMGQPLLVLLDEPSEGVAPVIVQQMARTIRALKAQGIGILLSEQNLPFAEAVADRACVLEQGRIVYS AGMAQLAGDAAARRQYLGV
Sequences:
>Translated_259_residues MNNQNDSASRLPDKALVAKTPLLEVADLHAWYGAAHILHGVSLSVGHGEVVALMGRNGAGKSTTLKGIAGLMERRSGRIE FLGQRIDRQPPHAIARRGLGYVPEDRRIFTDLTVLENLEVGRQRPRHWPDGTPAPLWTPERLFTLFPNLGEMPDRPGGRM SGGEQQMLTVARTLMGQPLLVLLDEPSEGVAPVIVQQMARTIRALKAQGIGILLSEQNLPFAEAVADRACVLEQGRIVYS AGMAQLAGDAAARRQYLGV >Mature_259_residues MNNQNDSASRLPDKALVAKTPLLEVADLHAWYGAAHILHGVSLSVGHGEVVALMGRNGAGKSTTLKGIAGLMERRSGRIE FLGQRIDRQPPHAIARRGLGYVPEDRRIFTDLTVLENLEVGRQRPRHWPDGTPAPLWTPERLFTLFPNLGEMPDRPGGRM SGGEQQMLTVARTLMGQPLLVLLDEPSEGVAPVIVQQMARTIRALKAQGIGILLSEQNLPFAEAVADRACVLEQGRIVYS AGMAQLAGDAAARRQYLGV
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0410
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27436953, Length=199, Percent_Identity=32.6633165829146, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI45446740, Length=198, Percent_Identity=29.7979797979798, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI47078218, Length=198, Percent_Identity=29.7979797979798, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI153792144, Length=201, Percent_Identity=32.3383084577114, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI27477115, Length=199, Percent_Identity=34.1708542713568, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI6005701, Length=199, Percent_Identity=33.6683417085427, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI150417984, Length=214, Percent_Identity=30.3738317757009, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI27262624, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI27262626, Length=199, Percent_Identity=30.1507537688442, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI27881501, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI30795238, Length=207, Percent_Identity=31.4009661835749, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI31657092, Length=213, Percent_Identity=28.169014084507, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI116734710, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI9955963, Length=224, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI105990541, Length=226, Percent_Identity=28.7610619469027, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI87082268, Length=245, Percent_Identity=41.6326530612245, Blast_Score=162, Evalue=2e-41, Organism=Escherichia coli, GI1789593, Length=238, Percent_Identity=34.453781512605, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI1789672, Length=236, Percent_Identity=29.6610169491525, Blast_Score=110, Evalue=7e-26, Organism=Escherichia coli, GI1787792, Length=231, Percent_Identity=29.4372294372294, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1790190, Length=229, Percent_Identity=27.0742358078603, Blast_Score=104, Evalue=6e-24, Organism=Escherichia coli, GI1790525, Length=238, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI1787029, Length=217, Percent_Identity=29.9539170506912, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1788225, Length=248, Percent_Identity=31.8548387096774, Blast_Score=100, Evalue=8e-23, Organism=Escherichia coli, GI1788761, Length=238, Percent_Identity=29.8319327731092, Blast_Score=100, Evalue=2e-22, Organism=Escherichia coli, GI1789864, Length=250, Percent_Identity=28.4, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1789991, Length=229, Percent_Identity=27.9475982532751, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1787370, Length=220, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI87081791, Length=236, Percent_Identity=28.3898305084746, Blast_Score=91, Evalue=9e-20, Organism=Escherichia coli, GI87081782, Length=221, Percent_Identity=31.2217194570136, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786319, Length=228, Percent_Identity=30.2631578947368, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI1790544, Length=253, Percent_Identity=27.6679841897233, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=31.5533980582524, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=30.316742081448, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1786872, Length=236, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=7e-19, Organism=Escherichia coli, GI1788472, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1787712, Length=225, Percent_Identity=27.5555555555556, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI48994943, Length=231, Percent_Identity=29.004329004329, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1786253, Length=239, Percent_Identity=27.6150627615063, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1788450, Length=224, Percent_Identity=30.3571428571429, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI48995001, Length=219, Percent_Identity=27.3972602739726, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788644, Length=252, Percent_Identity=29.3650793650794, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1788210, Length=233, Percent_Identity=27.4678111587983, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI87081834, Length=216, Percent_Identity=31.0185185185185, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1790467, Length=210, Percent_Identity=30.4761904761905, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI87081709, Length=248, Percent_Identity=26.2096774193548, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787105, Length=232, Percent_Identity=28.8793103448276, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1786698, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1786703, Length=209, Percent_Identity=29.1866028708134, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1788165, Length=219, Percent_Identity=28.310502283105, Blast_Score=72, Evalue=5e-14, Organism=Escherichia coli, GI1789586, Length=242, Percent_Identity=26.8595041322314, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI145693107, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787164, Length=219, Percent_Identity=29.2237442922374, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1786398, Length=207, Percent_Identity=25.6038647342995, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1788506, Length=218, Percent_Identity=27.9816513761468, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1786654, Length=218, Percent_Identity=27.0642201834862, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787182, Length=221, Percent_Identity=25.3393665158371, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI71992285, Length=210, Percent_Identity=26.1904761904762, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI115533608, Length=210, Percent_Identity=29.0476190476191, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17510237, Length=212, Percent_Identity=29.7169811320755, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71984940, Length=201, Percent_Identity=29.3532338308458, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565586, Length=208, Percent_Identity=27.8846153846154, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI193202349, Length=224, Percent_Identity=25.8928571428571, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI193209708, Length=238, Percent_Identity=24.3697478991597, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71988343, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71996550, Length=208, Percent_Identity=24.0384615384615, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193208177, Length=224, Percent_Identity=26.7857142857143, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17541710, Length=263, Percent_Identity=26.2357414448669, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6323959, Length=210, Percent_Identity=30, Blast_Score=78, Evalue=1e-15, Organism=Drosophila melanogaster, GI221512771, Length=220, Percent_Identity=30.4545454545455, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24666092, Length=232, Percent_Identity=28.0172413793103, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI28574150, Length=226, Percent_Identity=27.8761061946903, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI116007328, Length=226, Percent_Identity=27.8761061946903, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI21357907, Length=205, Percent_Identity=29.7560975609756, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI116007184, Length=211, Percent_Identity=27.4881516587678, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI221500365, Length=211, Percent_Identity=27.4881516587678, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24641565, Length=219, Percent_Identity=24.2009132420091, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24643674, Length=218, Percent_Identity=25.2293577981651, Blast_Score=69, Evalue=5e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 28129; Mature: 28129
Theoretical pI: Translated: 9.56; Mature: 9.56
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNNQNDSASRLPDKALVAKTPLLEVADLHAWYGAAHILHGVSLSVGHGEVVALMGRNGAG CCCCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCC KSTTLKGIAGLMERRSGRIEFLGQRIDRQPPHAIARRGLGYVPEDRRIFTDLTVLENLEV CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHH GRQRPRHWPDGTPAPLWTPERLFTLFPNLGEMPDRPGGRMSGGEQQMLTVARTLMGQPLL HHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE VLLDEPSEGVAPVIVQQMARTIRALKAQGIGILLSEQNLPFAEAVADRACVLEQGRIVYS EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEE AGMAQLAGDAAARRQYLGV HHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MNNQNDSASRLPDKALVAKTPLLEVADLHAWYGAAHILHGVSLSVGHGEVVALMGRNGAG CCCCCCCHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCCC KSTTLKGIAGLMERRSGRIEFLGQRIDRQPPHAIARRGLGYVPEDRRIFTDLTVLENLEV CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHH GRQRPRHWPDGTPAPLWTPERLFTLFPNLGEMPDRPGGRMSGGEQQMLTVARTLMGQPLL HHCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEE VLLDEPSEGVAPVIVQQMARTIRALKAQGIGILLSEQNLPFAEAVADRACVLEQGRIVYS EEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEE AGMAQLAGDAAARRQYLGV HHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]
Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2195019; 8041620; 9278503 [H]