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The map label for this gene is yfdE [H]

Identifier: 222109372

GI number: 222109372

Start: 168997

End: 170349

Strand: Direct

Name: yfdE [H]

Synonym: Dtpsy_0151

Alternate gene names: 222109372

Gene position: 168997-170349 (Clockwise)

Preceding gene: 222109370

Following gene: 222109377

Centisome position: 4.45

GC content: 70.73

Gene sequence:

>1353_bases
ATGCAAAGCCGCGGCGCCGGGGCGGGCCGTACCATGCGCCTTCCGCTCGGCAAACACCGCCTGTCCATGACCACCCCTGA
TTCCTCCTCTTCCCCAGGCGCAGGCCGCGCCGGCGCGCTCGGCCATCTGCGCGTGCTCGACCTATCGCGCGTGCTGGCCG
GCCCGTGGTGCACCCAGAACCTGGCCGACATGGGCGCCGACGTGATCAAGATCGAGAAGCCCGGCGACGGCGACGACACG
CGCCACTGGGGCCCGCCGTTCTTTCCCGATGCCGACGGCCAGCCGAGCGAACACGCCTGCTACTTCGCCGCCTGCAACCG
CAACAAGCGCTCCGTCACCGTGGACATGGCCACGCCCGAGGGGCAGCGGCTGATCCGCGAGCTGGCCCAGCAAAGCGATG
TGGTGGTGGAGAACTTCAAGACCGGCGGCCTCAAGCGCTACGGGCTGGACTACGAAAGCCTGTCGGCCCTGAACCCGCGC
CTGATCTACTGCTCGGTCACCGGCTTCGGCCACACCGGGCCGTATGCGCCGCGGGCCGGCTACGACCTGCTGATCCAGGC
CATGAGCGGCCTGATGAGCGTCACCGGCCATGCCGATGGCGAGCCTGGCGGCGGCCCGATGCGCGTGGGCGTGGCCGTGA
TCGACCTGTTCACCGGCATGTATGCCACCACCGCCATCCTGGGCGCGCTGGAGGCGCGCCACCGCACGGGACGCGGCCAG
CACATCGACATGGCGTTGCTGGACGTGGCCATGGCGGTGCTGGCCAACCAGGGTGCGGGCTTCCTCAACGCCGGCAACAT
TCCGAAGCGCCAGGGCAACACCCACCCCAGCGTCGTGCCCTACCAGGACTTTCCCACGCAGGACGGCAACATGCTGCTGG
CCATCGGCAACGACGGGCAGTTCGCACGCTTTTGCGAAGCGGCGGGTACCGACTGGGCCGGCGACGAACGCTTTGCCACC
AACGCCGGCCGGGTGACCCACCGTGAGACGCTGATCCCCCTGATGGCCGCCCTCACGCGCACGCGGCCCACGGCCGCCTG
GATCGCGCTGTTGGAGGACAAGGCCGTGCCCTGCGGCCCGATCAACCATGTCGGCCAGGCGTTCGACGATGCGCAGGTGC
GCGCACGCGGACTGCGCGTGGAGCAGCAGCGCTACCCCGGCGCCCAGCCGCCGGCCGGCGAGGTGGTCAACCGCGTGGTG
ACCACCGCCAGCCCGCTGCGCTTGTCCGATACGCCCGTCACCCTGCGCTATGCCCCGCCCCCACTGGGTCAGCACACCGA
CGAGGTGCTGCGCGAGCGGCTGGGGCTGGATGCCGCGCAACTGCAGGCGCTGCGCGCGCAGCGCGTGCTCTGA

Upstream 100 bases:

>100_bases
ATCAGGCGCAGATCCACAAGATCGAAATGCATGGCCATGGCCGGCATTGTAGAAAGCGCTGGATACCCTGGCGGCCCTGC
GTGAACGCCAGCTTTCACAA

Downstream 100 bases:

>100_bases
GGCAGCGTCAGAAGGCGTGGGCCACGCCCACGCCGAACGCCGTACGCGAGGGGTTGTGTTCGTAGCGCTGGTGCCCCAGG
CTCGCGTAGAGCATGGTGCG

Product: l-carnitine dehydratase/bile acid-inducible protein f

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MQSRGAGAGRTMRLPLGKHRLSMTTPDSSSSPGAGRAGALGHLRVLDLSRVLAGPWCTQNLADMGADVIKIEKPGDGDDT
RHWGPPFFPDADGQPSEHACYFAACNRNKRSVTVDMATPEGQRLIRELAQQSDVVVENFKTGGLKRYGLDYESLSALNPR
LIYCSVTGFGHTGPYAPRAGYDLLIQAMSGLMSVTGHADGEPGGGPMRVGVAVIDLFTGMYATTAILGALEARHRTGRGQ
HIDMALLDVAMAVLANQGAGFLNAGNIPKRQGNTHPSVVPYQDFPTQDGNMLLAIGNDGQFARFCEAAGTDWAGDERFAT
NAGRVTHRETLIPLMAALTRTRPTAAWIALLEDKAVPCGPINHVGQAFDDAQVRARGLRVEQQRYPGAQPPAGEVVNRVV
TTASPLRLSDTPVTLRYAPPPLGQHTDEVLRERLGLDAAQLQALRAQRVL

Sequences:

>Translated_450_residues
MQSRGAGAGRTMRLPLGKHRLSMTTPDSSSSPGAGRAGALGHLRVLDLSRVLAGPWCTQNLADMGADVIKIEKPGDGDDT
RHWGPPFFPDADGQPSEHACYFAACNRNKRSVTVDMATPEGQRLIRELAQQSDVVVENFKTGGLKRYGLDYESLSALNPR
LIYCSVTGFGHTGPYAPRAGYDLLIQAMSGLMSVTGHADGEPGGGPMRVGVAVIDLFTGMYATTAILGALEARHRTGRGQ
HIDMALLDVAMAVLANQGAGFLNAGNIPKRQGNTHPSVVPYQDFPTQDGNMLLAIGNDGQFARFCEAAGTDWAGDERFAT
NAGRVTHRETLIPLMAALTRTRPTAAWIALLEDKAVPCGPINHVGQAFDDAQVRARGLRVEQQRYPGAQPPAGEVVNRVV
TTASPLRLSDTPVTLRYAPPPLGQHTDEVLRERLGLDAAQLQALRAQRVL
>Mature_450_residues
MQSRGAGAGRTMRLPLGKHRLSMTTPDSSSSPGAGRAGALGHLRVLDLSRVLAGPWCTQNLADMGADVIKIEKPGDGDDT
RHWGPPFFPDADGQPSEHACYFAACNRNKRSVTVDMATPEGQRLIRELAQQSDVVVENFKTGGLKRYGLDYESLSALNPR
LIYCSVTGFGHTGPYAPRAGYDLLIQAMSGLMSVTGHADGEPGGGPMRVGVAVIDLFTGMYATTAILGALEARHRTGRGQ
HIDMALLDVAMAVLANQGAGFLNAGNIPKRQGNTHPSVVPYQDFPTQDGNMLLAIGNDGQFARFCEAAGTDWAGDERFAT
NAGRVTHRETLIPLMAALTRTRPTAAWIALLEDKAVPCGPINHVGQAFDDAQVRARGLRVEQQRYPGAQPPAGEVVNRVV
TTASPLRLSDTPVTLRYAPPPLGQHTDEVLRERLGLDAAQLQALRAQRVL

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=396, Percent_Identity=40.4040404040404, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI300863124, Length=421, Percent_Identity=37.7672209026128, Blast_Score=293, Evalue=2e-79,
Organism=Homo sapiens, GI300863126, Length=396, Percent_Identity=34.8484848484849, Blast_Score=246, Evalue=5e-65,
Organism=Homo sapiens, GI13376042, Length=421, Percent_Identity=33.9667458432304, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI266456254, Length=416, Percent_Identity=25.2403846153846, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI42794625, Length=416, Percent_Identity=25.2403846153846, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI266458397, Length=215, Percent_Identity=32.093023255814, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI266458393, Length=215, Percent_Identity=32.093023255814, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI266458395, Length=152, Percent_Identity=34.2105263157895, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=34.2105263157895, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI87082093, Length=345, Percent_Identity=37.3913043478261, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788717, Length=433, Percent_Identity=30.4849884526559, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1786222, Length=263, Percent_Identity=27.7566539923954, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115535051, Length=351, Percent_Identity=24.7863247863248, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32564160, Length=260, Percent_Identity=25.7692307692308, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648431, Length=409, Percent_Identity=43.7652811735941, Blast_Score=333, Evalue=2e-91,
Organism=Drosophila melanogaster, GI24585488, Length=215, Percent_Identity=30.2325581395349, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 48166; Mature: 48166

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRGAGAGRTMRLPLGKHRLSMTTPDSSSSPGAGRAGALGHLRVLDLSRVLAGPWCTQN
CCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
LADMGADVIKIEKPGDGDDTRHWGPPFFPDADGQPSEHACYFAACNRNKRSVTVDMATPE
HHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCC
GQRLIRELAQQSDVVVENFKTGGLKRYGLDYESLSALNPRLIYCSVTGFGHTGPYAPRAG
HHHHHHHHHHHCCEEEEHHCCCCEEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCH
YDLLIQAMSGLMSVTGHADGEPGGGPMRVGVAVIDLFTGMYATTAILGALEARHRTGRGQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HIDMALLDVAMAVLANQGAGFLNAGNIPKRQGNTHPSVVPYQDFPTQDGNMLLAIGNDGQ
EEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCCC
FARFCEAAGTDWAGDERFATNAGRVTHRETLIPLMAALTRTRPTAAWIALLEDKAVPCGP
HHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
INHVGQAFDDAQVRARGLRVEQQRYPGAQPPAGEVVNRVVTTASPLRLSDTPVTLRYAPP
HHHHHHHCCHHHHHHHCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCEEEEECCC
PLGQHTDEVLRERLGLDAAQLQALRAQRVL
CCCCCHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQSRGAGAGRTMRLPLGKHRLSMTTPDSSSSPGAGRAGALGHLRVLDLSRVLAGPWCTQN
CCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
LADMGADVIKIEKPGDGDDTRHWGPPFFPDADGQPSEHACYFAACNRNKRSVTVDMATPE
HHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCC
GQRLIRELAQQSDVVVENFKTGGLKRYGLDYESLSALNPRLIYCSVTGFGHTGPYAPRAG
HHHHHHHHHHHCCEEEEHHCCCCEEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCH
YDLLIQAMSGLMSVTGHADGEPGGGPMRVGVAVIDLFTGMYATTAILGALEARHRTGRGQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
HIDMALLDVAMAVLANQGAGFLNAGNIPKRQGNTHPSVVPYQDFPTQDGNMLLAIGNDGQ
EEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCEEEEECCCCC
FARFCEAAGTDWAGDERFATNAGRVTHRETLIPLMAALTRTRPTAAWIALLEDKAVPCGP
HHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
INHVGQAFDDAQVRARGLRVEQQRYPGAQPPAGEVVNRVVTTASPLRLSDTPVTLRYAPP
HHHHHHHCCHHHHHHHCCEEHHHHCCCCCCCHHHHHHHHHHCCCCCEECCCCEEEEECCC
PLGQHTDEVLRERLGLDAAQLQALRAQRVL
CCCCCHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]