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The map label for this gene is 222109368

Identifier: 222109368

GI number: 222109368

Start: 165132

End: 166340

Strand: Direct

Name: 222109368

Synonym: Dtpsy_0147

Alternate gene names: NA

Gene position: 165132-166340 (Clockwise)

Preceding gene: 222109367

Following gene: 222109369

Centisome position: 4.35

GC content: 70.72

Gene sequence:

>1209_bases
ATGAGCCGCGTTCCGCAATCCCCCCTGGACGCCGCCGCCGTGAACCGGCCGCTGCGCGGCCGCGCAGCCATCGTCGGCGC
CGCCACCTACGGCTGCGGCGAGGCGCCCGGCATGGACGACATGACGCTGCTGGTGCGTGCAGCACACGCGGCCGTGGCCG
ACGCGGGGCTGACCATGCAGGACATCGACGGCCTGGCCACCTGCAGTGTGAACGCCAGCATGTGGACCATGCCGGTGATC
GAACACCTCGGCATCAACCCGACCTATGTGGACGGCACGATGATCGGTGGCTCCAGCTTCATCGCCCACCTGCTGCCCGC
CATCCGCGCGCTGGAGGCCGGGCAGTGCAAGGCCGTGCTGGTGTGCTACGGCAGCGCGCAGCGCTCGGCCACCTTCGGGC
GCAAGGAAAGCGTGGCCGCACGCCGCTTCCTGGACCCGCAGCCGTACGAATTCCCGTATGAGCCGGTGCTGCCCGTGTCC
GCCTATGCGCTGGCCGCCGCGCGCCACATGCACGAATTCGGCACCACGCGCGAACAACTGGCCGAGGTGGCCGTGGCCGC
ACGTGCCTGGGCGCAGCAGAACCCCGAGGCGTTCATGCGCGACCCGCTCACCATCGAGGATGTGCTGGCGGCCCGGCCGA
TCGCCAGCCCGCTCACCGTGCGCGACTGCTGCCTGGTGACGGACGGTGGCGGCGCTCTCGTGCTCACCCGCGCCGAGCGC
GCGCGCGACCTGCCCAACCCGCCCGTCTATGTGCTGGGCAATGCCACGGCCATCTGGAACCGCCAGATCTCCTGCATGCC
CGACCTGACGACCACCGCGGCAGCGCAGTCGGGCGCCCAGGCCTTCGCGATGGCGGGTTTGCAGGCCAAAGACATGGACA
TGGCCCAGGTGTACGACGCTTTCACCATCAACACCCTGCTGTTCCTGGAAGACCTGGGCTTCTGTGCCAAGGGCGAGGCC
GGCGCCTTCGTGCAGAACGGCGGCATCGCGCCCGGCGGGCGCCTGGCCGTGAACACCAACGGCGGCGGCCTGTCGTGCGT
GCACCCGGGCATGTACGGCATCTTTGCGCTGATCGAGGCCGTGCGCCAGCTGCGCGGCGAGGCCGGCGCGCGCCAGCTAT
CGCGTCATGACACCGCCGTGGTGCATGGCAACGGCGGCACGCTGTCCAGCCAGTCCACCGCCGTGCTCGGCACCGCCGAC
ACCCTCTGA

Upstream 100 bases:

>100_bases
CCGAAGACGTGCGCATCGGCCAGCGGGTGCAGGCCCGCGTGGCGCAGAAGGACGGGCGTGGCCTGGTGCTGTTCCAGCCC
GCAGCGCAAGGGGGTGCCGC

Downstream 100 bases:

>100_bases
ACCCGCATACCGAAGAAAGAACCCTCATGATCCGCGACCCAGACATCTTGGAAGCCCTGCTCGACAGCGTGCGCCGCTTT
GTGCGAGAACGCCTGGTGCC

Product: thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSRVPQSPLDAAAVNRPLRGRAAIVGAATYGCGEAPGMDDMTLLVRAAHAAVADAGLTMQDIDGLATCSVNASMWTMPVI
EHLGINPTYVDGTMIGGSSFIAHLLPAIRALEAGQCKAVLVCYGSAQRSATFGRKESVAARRFLDPQPYEFPYEPVLPVS
AYALAAARHMHEFGTTREQLAEVAVAARAWAQQNPEAFMRDPLTIEDVLAARPIASPLTVRDCCLVTDGGGALVLTRAER
ARDLPNPPVYVLGNATAIWNRQISCMPDLTTTAAAQSGAQAFAMAGLQAKDMDMAQVYDAFTINTLLFLEDLGFCAKGEA
GAFVQNGGIAPGGRLAVNTNGGGLSCVHPGMYGIFALIEAVRQLRGEAGARQLSRHDTAVVHGNGGTLSSQSTAVLGTAD
TL

Sequences:

>Translated_402_residues
MSRVPQSPLDAAAVNRPLRGRAAIVGAATYGCGEAPGMDDMTLLVRAAHAAVADAGLTMQDIDGLATCSVNASMWTMPVI
EHLGINPTYVDGTMIGGSSFIAHLLPAIRALEAGQCKAVLVCYGSAQRSATFGRKESVAARRFLDPQPYEFPYEPVLPVS
AYALAAARHMHEFGTTREQLAEVAVAARAWAQQNPEAFMRDPLTIEDVLAARPIASPLTVRDCCLVTDGGGALVLTRAER
ARDLPNPPVYVLGNATAIWNRQISCMPDLTTTAAAQSGAQAFAMAGLQAKDMDMAQVYDAFTINTLLFLEDLGFCAKGEA
GAFVQNGGIAPGGRLAVNTNGGGLSCVHPGMYGIFALIEAVRQLRGEAGARQLSRHDTAVVHGNGGTLSSQSTAVLGTAD
TL
>Mature_401_residues
SRVPQSPLDAAAVNRPLRGRAAIVGAATYGCGEAPGMDDMTLLVRAAHAAVADAGLTMQDIDGLATCSVNASMWTMPVIE
HLGINPTYVDGTMIGGSSFIAHLLPAIRALEAGQCKAVLVCYGSAQRSATFGRKESVAARRFLDPQPYEFPYEPVLPVSA
YALAAARHMHEFGTTREQLAEVAVAARAWAQQNPEAFMRDPLTIEDVLAARPIASPLTVRDCCLVTDGGGALVLTRAERA
RDLPNPPVYVLGNATAIWNRQISCMPDLTTTAAAQSGAQAFAMAGLQAKDMDMAQVYDAFTINTLLFLEDLGFCAKGEAG
AFVQNGGIAPGGRLAVNTNGGGLSCVHPGMYGIFALIEAVRQLRGEAGARQLSRHDTAVVHGNGGTLSSQSTAVLGTADT
L

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344760, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI19923233, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI302344767, Length=248, Percent_Identity=28.6290322580645, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI302344762, Length=248, Percent_Identity=28.6290322580645, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI55956775, Length=211, Percent_Identity=26.5402843601896, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537653, Length=393, Percent_Identity=23.9185750636132, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921506, Length=234, Percent_Identity=29.4871794871795, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24585051, Length=234, Percent_Identity=29.4871794871795, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: NA

Molecular weight: Translated: 42085; Mature: 41954

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVPQSPLDAAAVNRPLRGRAAIVGAATYGCGEAPGMDDMTLLVRAAHAAVADAGLTMQ
CCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
DIDGLATCSVNASMWTMPVIEHLGINPTYVDGTMIGGSSFIAHLLPAIRALEAGQCKAVL
HCCCEEEEECCCCHHHHHHHHHCCCCCEEECCEEECHHHHHHHHHHHHHHHCCCCCCEEE
VCYGSAQRSATFGRKESVAARRFLDPQPYEFPYEPVLPVSAYALAAARHMHEFGTTREQL
EEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AEVAVAARAWAQQNPEAFMRDPLTIEDVLAARPIASPLTVRDCCLVTDGGGALVLTRAER
HHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECHH
ARDLPNPPVYVLGNATAIWNRQISCMPDLTTTAAAQSGAQAFAMAGLQAKDMDMAQVYDA
HCCCCCCCEEEEECCEEEECCCEECCCCCHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHH
FTINTLLFLEDLGFCAKGEAGAFVQNGGIAPGGRLAVNTNGGGLSCVHPGMYGIFALIEA
HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHH
VRQLRGEAGARQLSRHDTAVVHGNGGTLSSQSTAVLGTADTL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SRVPQSPLDAAAVNRPLRGRAAIVGAATYGCGEAPGMDDMTLLVRAAHAAVADAGLTMQ
CCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHH
DIDGLATCSVNASMWTMPVIEHLGINPTYVDGTMIGGSSFIAHLLPAIRALEAGQCKAVL
HCCCEEEEECCCCHHHHHHHHHCCCCCEEECCEEECHHHHHHHHHHHHHHHCCCCCCEEE
VCYGSAQRSATFGRKESVAARRFLDPQPYEFPYEPVLPVSAYALAAARHMHEFGTTREQL
EEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH
AEVAVAARAWAQQNPEAFMRDPLTIEDVLAARPIASPLTVRDCCLVTDGGGALVLTRAER
HHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECHH
ARDLPNPPVYVLGNATAIWNRQISCMPDLTTTAAAQSGAQAFAMAGLQAKDMDMAQVYDA
HCCCCCCCEEEEECCEEEECCCEECCCCCHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHH
FTINTLLFLEDLGFCAKGEAGAFVQNGGIAPGGRLAVNTNGGGLSCVHPGMYGIFALIEA
HHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHH
VRQLRGEAGARQLSRHDTAVVHGNGGTLSSQSTAVLGTADTL
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]