Click here to switch to the map view.

The map label for this gene is fecD [C]

Identifier: 222102883

GI number: 222102883

Start: 561073

End: 562137

Strand: Direct

Name: fecD [C]

Synonym: Avi_7623

Alternate gene names: 222102883

Gene position: 561073-562137 (Clockwise)

Preceding gene: 222102882

Following gene: 222102884

Centisome position: 88.81

GC content: 60.09

Gene sequence:

>1065_bases
ATGACGACCTTTTCCGCAGAGATTGATGGGATGCGCGACGGCTATCGCCGCGCATCCGCTCGTCGGACTTTAGTCATGAT
CGGCGCCCTCATTTGCCTTGTTTTGCTGATGGTGCTCGATCTCACCACCGGTCCATCCGGCATGCCGCTTGCCGAAGTAT
GGCATGGGCTTCTCGCCGGGCCTGCCGGTGACGACCGCATGGTTGCAACGATCCTGTGGCAATTGCGCATGCCGCAAACT
GTCATGGGCGTCCTGGTCGGCGCCTGCCTCGGCCTTGCCGGCCTGCAAATGCAGACGATCCTTGGCAATCCGCTGGCCAG
CCCCTTCACACTCGGCTTTTCGGCAGCGGCAGGCTTTGGCGCGGCATTAGCGATCATGTTCGGCTCGCTCATCCCGCTGC
CCGGTTTCATCGTCATCCCCGCCTGCGCCTTTGTGATGACCCTGGTGGCCTGTGCTCTGGTCTATCTGATCGCGCGGCTT
CGTGGCGCGACACCGGAAATCCTCGTGCTTGGAGGCATTGCGGTGTTGTTCTTCTTCCAATCGCTCCAGTCCCTGCTTCA
GTTTCTGGCGTCACCGGAAGTCTTGCAGCAGATTGTCTTCTGGCTATTCGGCAGCCTCTTGAAGTCAAGCTGGACGAGCG
TCACAGTGAGTGCTGCGATTGCATGCGCCTGCCTTCCCTTCATTACCCGTAGCACCTGGGCCTTGACCACGTTGCGTCTC
GGAGATGCCAATGCCCGAAGCCTCGGGCTATCGGTTGAGAAAATCCGTCGGAATACCTTCCTGATCGTGGCATTGTTGAC
AGCCGGAGCCGTCTCCTTCGTCGGAACCATCGGCTTTGTTGGGCTCATCGCACCGCATGTTGCCCGCGCACTCGTCGGAG
AGGACCATCGGTTCTCCCTGCCGCTGGCAGCCCTAACGGGAGCCATCATTTTGATCGGCGCGTGCGTGTTCGGAAAATTC
ATCTCTCCGGCTGCCGTCATTCCGGTCGGCATCATCACGGCCATCGCAGGCGTACCGATGCTGTTTGTCGTCATCGCCAA
ACGCGGTCAGCGAGGCCTGACATGA

Upstream 100 bases:

>100_bases
AGAACGTCGATCCGGCAAAGAACATTGCTGATTATTATAATAATTGGCTGCCGATCAAGGCCGACGGTGTGTTTGTTCTC
CCTTATGAAGCGAACGGACA

Downstream 100 bases:

>100_bases
CGGCGCGGCTGGTCTTGAGAGACGTAAGCGTCCAACATGGGCGCACCACGATTGTTTCAGGTGTATCGACCTCTATTGCT
GCTGGGCAGATCGTTGGCCT

Product: ABC transporter membrane spanning protein (iron)

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTTFSAEIDGMRDGYRRASARRTLVMIGALICLVLLMVLDLTTGPSGMPLAEVWHGLLAGPAGDDRMVATILWQLRMPQT
VMGVLVGACLGLAGLQMQTILGNPLASPFTLGFSAAAGFGAALAIMFGSLIPLPGFIVIPACAFVMTLVACALVYLIARL
RGATPEILVLGGIAVLFFFQSLQSLLQFLASPEVLQQIVFWLFGSLLKSSWTSVTVSAAIACACLPFITRSTWALTTLRL
GDANARSLGLSVEKIRRNTFLIVALLTAGAVSFVGTIGFVGLIAPHVARALVGEDHRFSLPLAALTGAIILIGACVFGKF
ISPAAVIPVGIITAIAGVPMLFVVIAKRGQRGLT

Sequences:

>Translated_354_residues
MTTFSAEIDGMRDGYRRASARRTLVMIGALICLVLLMVLDLTTGPSGMPLAEVWHGLLAGPAGDDRMVATILWQLRMPQT
VMGVLVGACLGLAGLQMQTILGNPLASPFTLGFSAAAGFGAALAIMFGSLIPLPGFIVIPACAFVMTLVACALVYLIARL
RGATPEILVLGGIAVLFFFQSLQSLLQFLASPEVLQQIVFWLFGSLLKSSWTSVTVSAAIACACLPFITRSTWALTTLRL
GDANARSLGLSVEKIRRNTFLIVALLTAGAVSFVGTIGFVGLIAPHVARALVGEDHRFSLPLAALTGAIILIGACVFGKF
ISPAAVIPVGIITAIAGVPMLFVVIAKRGQRGLT
>Mature_353_residues
TTFSAEIDGMRDGYRRASARRTLVMIGALICLVLLMVLDLTTGPSGMPLAEVWHGLLAGPAGDDRMVATILWQLRMPQTV
MGVLVGACLGLAGLQMQTILGNPLASPFTLGFSAAAGFGAALAIMFGSLIPLPGFIVIPACAFVMTLVACALVYLIARLR
GATPEILVLGGIAVLFFFQSLQSLLQFLASPEVLQQIVFWLFGSLLKSSWTSVTVSAAIACACLPFITRSTWALTTLRLG
DANARSLGLSVEKIRRNTFLIVALLTAGAVSFVGTIGFVGLIAPHVARALVGEDHRFSLPLAALTGAIILIGACVFGKFI
SPAAVIPVGIITAIAGVPMLFVVIAKRGQRGLT

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=287, Percent_Identity=34.1463414634146, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786805, Length=289, Percent_Identity=35.9861591695502, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1788004, Length=279, Percent_Identity=31.1827956989247, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790741, Length=284, Percent_Identity=30.6338028169014, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=31.095406360424, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786804, Length=312, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37067; Mature: 36936

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFSAEIDGMRDGYRRASARRTLVMIGALICLVLLMVLDLTTGPSGMPLAEVWHGLLAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
PAGDDRMVATILWQLRMPQTVMGVLVGACLGLAGLQMQTILGNPLASPFTLGFSAAAGFG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHHHH
AALAIMFGSLIPLPGFIVIPACAFVMTLVACALVYLIARLRGATPEILVLGGIAVLFFFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
SLQSLLQFLASPEVLQQIVFWLFGSLLKSSWTSVTVSAAIACACLPFITRSTWALTTLRL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEE
GDANARSLGLSVEKIRRNTFLIVALLTAGAVSFVGTIGFVGLIAPHVARALVGEDHRFSL
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLAALTGAIILIGACVFGKFISPAAVIPVGIITAIAGVPMLFVVIAKRGQRGLT
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTFSAEIDGMRDGYRRASARRTLVMIGALICLVLLMVLDLTTGPSGMPLAEVWHGLLAG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCC
PAGDDRMVATILWQLRMPQTVMGVLVGACLGLAGLQMQTILGNPLASPFTLGFSAAAGFG
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCHHHHHHHH
AALAIMFGSLIPLPGFIVIPACAFVMTLVACALVYLIARLRGATPEILVLGGIAVLFFFQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
SLQSLLQFLASPEVLQQIVFWLFGSLLKSSWTSVTVSAAIACACLPFITRSTWALTTLRL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEE
GDANARSLGLSVEKIRRNTFLIVALLTAGAVSFVGTIGFVGLIAPHVARALVGEDHRFSL
CCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLAALTGAIILIGACVFGKFISPAAVIPVGIITAIAGVPMLFVVIAKRGQRGLT
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]