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The map label for this gene is allB [H]

Identifier: 222102816

GI number: 222102816

Start: 481492

End: 482868

Strand: Direct

Name: allB [H]

Synonym: Avi_7538

Alternate gene names: 222102816

Gene position: 481492-482868 (Clockwise)

Preceding gene: 222102815

Following gene: 222102817

Centisome position: 76.21

GC content: 58.17

Gene sequence:

>1377_bases
ATGAGTGATTTCGACAGAGTGGTGCGCGGAACCCTCGTGACCGAGGACGGGATCACTGAAAATGGCTTTGTGGCCATCCG
CGACGGTATCATCGCAGCCCTTGGAAGCGGTTCGGCTCCAGCAGCCAGAGAGGTCGATGATTTCGGCTCGGCGCTGATTC
TGCCCGGCATCATTGATGGGCAGGTTCATTCCCGCTCGCAAAAGGATCAGGAGGATTTTATCTGGTCCACCCGATCCGCT
GCGGCAGGTGGCGTCACCACAATCGTCGACATGCCCTATGATGCTGGCGGAAAATTGATCTGCACGGCAGAGCTTTTGAC
AGAAAAGGCCGAAAGTGCAGCCGAGCAGGCCCGTGTGGATTTTGCGCTCTACGGCACCATTCGCCCCTCTGATGGCCCGA
AGCACATTGCTGAGATGGCAGATGCAGGGGCGGCAGGCTTTAAATTTTCAACCTTTGAGACCGATCCAAACCGTTTTCCG
CGCATTCCAACGCCACTGCTCTATGCCGCCTTTGCTGAAGTGGCCAAGACCGGATTGATTGCCGGTGTTCACAACGAAAA
TGACGAATGCGTCAAGGTGTGGAGCGAAGCGGTGAAGGCCACAGGCCGCACGGACTATCTGACCCATGGAGAAAGCCGTC
CACCGATCGCCGAAACACTGGCCATCGCCGAGGTTTATGAAATTGCAGCCGCCACCGGATGCCCGGCCCATATCGTGCAT
TGCTCGGTTGGGCGCGGCTATGAGCTCGCGCAAGCCTACCGCGCCCAAGGTGTGGACGCGACCATTGAGGCCTGCATCCA
TTACCTCGTGTGTAGCGAGGAGGAAGACGTGTCGCGTCTGCTGGGTCGCGCAAAATGCAATCCGCCCATTCGTTCCGCCA
AGGAGCGTGAGAAGCTCTGGCAGCATCTTGCAGCAGGCCATATCACCATAGTCTCTACCGACCATGTATCATGGAGCCTT
GCGGCAAAATCCGCGACTGTGATGCTGGAAAATTCTTCCGGCATGCCGGGTCTTGAGGTGCTCGCAAGCCTGCTGCTGGA
CGGGCTGACAGATCGCGGCCTGCCACTCACCTTTGCCGCAAAACTGCTGTGCGGTAATCCGGCCCGGCTGTTTCGCCTGA
CGGCCCAAAAAGGCGCGCTGTCTATTGGTCTGGATGCGGATATTGCGGTCTTTGCAGAGCGGCCAAGAATTTACGATGCG
GCGGCCAGCGGCCATAACGTGGTGGGTTGGAGCCCCTATGAGGGCAAGCGTATCCGCCACACGGCCATTGCAACCTTTCT
GCGCGGCCAGATGATTTATGACGGCAAGGATGTTCTGGCAGCACCCGGAACGGGCCGCTTTATCAAGCCCACCCGCGCCC
TATCAAAAGTAGCTTGA

Upstream 100 bases:

>100_bases
GCGGTGTGCCTGAGGGGCAGCGTGGGGCAGCGCTTCTGTTTTTTCAAGCCGCTGCCCATGGCGCACATATTCAAAATCAT
GACCAAGGAAGAAGGCTGCT

Downstream 100 bases:

>100_bases
TCCGATGGCCAATATGCAATCCGTCCCCAGCATTGACCGCACAAAGCTGCAAGCCGATTTCGATGCGCTGGCAGCCCTGA
CAGAGCCGGGCCGCCCTTGG

Product: allantoinase protein

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MSDFDRVVRGTLVTEDGITENGFVAIRDGIIAALGSGSAPAAREVDDFGSALILPGIIDGQVHSRSQKDQEDFIWSTRSA
AAGGVTTIVDMPYDAGGKLICTAELLTEKAESAAEQARVDFALYGTIRPSDGPKHIAEMADAGAAGFKFSTFETDPNRFP
RIPTPLLYAAFAEVAKTGLIAGVHNENDECVKVWSEAVKATGRTDYLTHGESRPPIAETLAIAEVYEIAAATGCPAHIVH
CSVGRGYELAQAYRAQGVDATIEACIHYLVCSEEEDVSRLLGRAKCNPPIRSAKEREKLWQHLAAGHITIVSTDHVSWSL
AAKSATVMLENSSGMPGLEVLASLLLDGLTDRGLPLTFAAKLLCGNPARLFRLTAQKGALSIGLDADIAVFAERPRIYDA
AASGHNVVGWSPYEGKRIRHTAIATFLRGQMIYDGKDVLAAPGTGRFIKPTRALSKVA

Sequences:

>Translated_458_residues
MSDFDRVVRGTLVTEDGITENGFVAIRDGIIAALGSGSAPAAREVDDFGSALILPGIIDGQVHSRSQKDQEDFIWSTRSA
AAGGVTTIVDMPYDAGGKLICTAELLTEKAESAAEQARVDFALYGTIRPSDGPKHIAEMADAGAAGFKFSTFETDPNRFP
RIPTPLLYAAFAEVAKTGLIAGVHNENDECVKVWSEAVKATGRTDYLTHGESRPPIAETLAIAEVYEIAAATGCPAHIVH
CSVGRGYELAQAYRAQGVDATIEACIHYLVCSEEEDVSRLLGRAKCNPPIRSAKEREKLWQHLAAGHITIVSTDHVSWSL
AAKSATVMLENSSGMPGLEVLASLLLDGLTDRGLPLTFAAKLLCGNPARLFRLTAQKGALSIGLDADIAVFAERPRIYDA
AASGHNVVGWSPYEGKRIRHTAIATFLRGQMIYDGKDVLAAPGTGRFIKPTRALSKVA
>Mature_457_residues
SDFDRVVRGTLVTEDGITENGFVAIRDGIIAALGSGSAPAAREVDDFGSALILPGIIDGQVHSRSQKDQEDFIWSTRSAA
AGGVTTIVDMPYDAGGKLICTAELLTEKAESAAEQARVDFALYGTIRPSDGPKHIAEMADAGAAGFKFSTFETDPNRFPR
IPTPLLYAAFAEVAKTGLIAGVHNENDECVKVWSEAVKATGRTDYLTHGESRPPIAETLAIAEVYEIAAATGCPAHIVHC
SVGRGYELAQAYRAQGVDATIEACIHYLVCSEEEDVSRLLGRAKCNPPIRSAKEREKLWQHLAAGHITIVSTDHVSWSLA
AKSATVMLENSSGMPGLEVLASLLLDGLTDRGLPLTFAAKLLCGNPARLFRLTAQKGALSIGLDADIAVFAERPRIYDAA
ASGHNVVGWSPYEGKRIRHTAIATFLRGQMIYDGKDVLAAPGTGRFIKPTRALSKVA

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=472, Percent_Identity=26.4830508474576, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI18105007, Length=434, Percent_Identity=27.6497695852535, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI190194363, Length=461, Percent_Identity=24.5119305856833, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4503377, Length=465, Percent_Identity=24.3010752688172, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4503051, Length=471, Percent_Identity=23.1422505307856, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI62422571, Length=468, Percent_Identity=22.8632478632479, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4503379, Length=464, Percent_Identity=22.6293103448276, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI19923821, Length=483, Percent_Identity=25.4658385093168, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI87082175, Length=460, Percent_Identity=29.1304347826087, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1786722, Length=458, Percent_Identity=29.4759825327511, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71989490, Length=467, Percent_Identity=26.5524625267666, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193204318, Length=402, Percent_Identity=24.8756218905473, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17539558, Length=472, Percent_Identity=25.8474576271186, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322218, Length=423, Percent_Identity=28.6052009456265, Blast_Score=139, Evalue=6e-34,
Organism=Drosophila melanogaster, GI18859883, Length=440, Percent_Identity=28.6363636363636, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24642586, Length=429, Percent_Identity=26.3403263403263, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI221377917, Length=462, Percent_Identity=26.4069264069264, Blast_Score=92, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 48818; Mature: 48687

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFDRVVRGTLVTEDGITENGFVAIRDGIIAALGSGSAPAAREVDDFGSALILPGIIDG
CCHHHHHHHCEEEECCCCCCCCEEEEECCEEEEECCCCCCCHHHHHHCCCEEEECCEECC
QVHSRSQKDQEDFIWSTRSAAAGGVTTIVDMPYDAGGKLICTAELLTEKAESAAEQARVD
CHHCCCCCCHHHHHEECCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHEE
FALYGTIRPSDGPKHIAEMADAGAAGFKFSTFETDPNRFPRIPTPLLYAAFAEVAKTGLI
EEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCEE
AGVHNENDECVKVWSEAVKATGRTDYLTHGESRPPIAETLAIAEVYEIAAATGCPAHIVH
EEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
CSVGRGYELAQAYRAQGVDATIEACIHYLVCSEEEDVSRLLGRAKCNPPIRSAKEREKLW
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
QHLAAGHITIVSTDHVSWSLAAKSATVMLENSSGMPGLEVLASLLLDGLTDRGLPLTFAA
HHHHCCCEEEEEECCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
KLLCGNPARLFRLTAQKGALSIGLDADIAVFAERPRIYDAAASGHNVVGWSPYEGKRIRH
HHHCCCHHHHEEEECCCCCEEECCCCCEEEEECCCCEEECCCCCCCCEECCCCCCCCHHH
TAIATFLRGQMIYDGKDVLAAPGTGRFIKPTRALSKVA
HHHHHHHHCCEEECCCCEEECCCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
SDFDRVVRGTLVTEDGITENGFVAIRDGIIAALGSGSAPAAREVDDFGSALILPGIIDG
CHHHHHHHCEEEECCCCCCCCEEEEECCEEEEECCCCCCCHHHHHHCCCEEEECCEECC
QVHSRSQKDQEDFIWSTRSAAAGGVTTIVDMPYDAGGKLICTAELLTEKAESAAEQARVD
CHHCCCCCCHHHHHEECCCCCCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHEE
FALYGTIRPSDGPKHIAEMADAGAAGFKFSTFETDPNRFPRIPTPLLYAAFAEVAKTGLI
EEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCEE
AGVHNENDECVKVWSEAVKATGRTDYLTHGESRPPIAETLAIAEVYEIAAATGCPAHIVH
EEECCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
CSVGRGYELAQAYRAQGVDATIEACIHYLVCSEEEDVSRLLGRAKCNPPIRSAKEREKLW
ECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
QHLAAGHITIVSTDHVSWSLAAKSATVMLENSSGMPGLEVLASLLLDGLTDRGLPLTFAA
HHHHCCCEEEEEECCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHH
KLLCGNPARLFRLTAQKGALSIGLDADIAVFAERPRIYDAAASGHNVVGWSPYEGKRIRH
HHHCCCHHHHEEEECCCCCEEECCCCCEEEEECCCCEEECCCCCCCCEECCCCCCCCHHH
TAIATFLRGQMIYDGKDVLAAPGTGRFIKPTRALSKVA
HHHHHHHHCCEEECCCCEEECCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA