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The map label for this gene is nodT [H]

Identifier: 222102783

GI number: 222102783

Start: 444788

End: 446260

Strand: Reverse

Name: nodT [H]

Synonym: Avi_7487

Alternate gene names: 222102783

Gene position: 446260-444788 (Counterclockwise)

Preceding gene: 222102786

Following gene: 222102782

Centisome position: 70.64

GC content: 56.28

Gene sequence:

>1473_bases
ATGACGCCAGCACATGACAATGCACTTCAACCGAACAATAAGCTGCATGGCAAATGGTGGCTCAGTCTGATTGTTGTACC
CTTGTCGGCCTGCGTGGCGGTGACCCAGTCAAATGTGGATATTTCCAAATTGGCAAACCGCTGGCATGCGACGTTGCCGC
ATTCGGGCAGCACCGCACAGCTGGTTGATTGGTGGAACACCTTTAATGATCCTGCCCTCTCAGAGCTTTTGCGCACCGCC
GAAGCCAACAGCCCCACCCTTGAATCCGCAGTTGCCGAGATTGAAGAAGCCCGCGCCACCTTGGCCTCATCAAAGGCGGA
CTATTTCCCATCCCTGACCGGTTCTGGATCCTATGACCGTTCTGGAACGCGGGGATCGAAAGCCAATCGCGTGGCCCCCT
CCACCACGGGCACCGGAGAGCTGGATGCATCTTGGGAGCTGGATTTTTTCGGCAAGACACGCAACACCGTCGAGGCCGCC
CGCCAGCGCGTCGCCGAGGAAACGGCGGACTGGTATGATGCCCGCGTAACGCTTGCCGCTGAGGTTGCCGATGATTACGT
GCAATACAAGGGATGTCGGCAGTTGCAGGGCATTTATGCAGCCGAGCTGGTTTCTCAACAACAGACGGTCAAGGCGACAG
AGGTTTCCACCGCATCCGGATTGAAATCGAGTTCCGATCTGGCCCTGATCAAAGCAAGTGCGGCGAGCACGTCTTCGTCC
CTGAAGTCACAGGTGGCGGATTGCGAGGTTCTGATCAAATCGATTACCGAACTCGTTGCTGTTGATGAAGACAAAGTGCG
CGATATTCTCAATAAAAGCTCGTCGAAAATACCGCGCCCTGCGAAACTGTCCGTTGATGCAATTCCGGCCAATGTTATCC
GGCAAAGACCGGATGTGAATGCGCTGGAAAAAGAAGCCGCCGCCTCGCTTGCCGATGTCGCAACCGCCAAAGCCGATCTT
TACCCAAGCTTTTCTCTCAGCGGCACGCTGACGGCGAGCCATTCGACATCCAGTGGCACAAGCTTGCCATGGTCGTTTGG
GCCAGCGGTTTCAATCCCGATTTTTGACGGGGGATCACTTCGCGCCACCGTCAAATATAAGGAAGCGGCCTATAAGGCGG
CCATTGCCAGTTACAAGTCCGGTGTTCTGACCGCCATCAACGCCGTGGAAACGGCGATGGTGAATGTCGATAGCACGGAG
CGCCAGATTGGTGATGCTGTGGTCGCGGCAAAGAACTATCGGGCGTATTTCAAAGCCATAGACACCAATTGGAAAGCGGG
CGGGGCAAGTGTTCTTGACCGCGAAGATGCGCGCCGCGAGTTGCAGGCCGCCGAGTTAACGCTTGTGGAAAATCAACGCG
ATGCCGTGCGCGATTGGATCGCTCTTTACAAGGCGATGGGCGGCGGCTGGACCCCGAATGCAACGGGCGGCGAGATGGCA
AGTGACGTAGATGCCAAAGGAGTAAAACAGTGA

Upstream 100 bases:

>100_bases
GCAAGTGTTATTTTACCCAATTTTACACATCCCTGACGGCACTTAACATTCACATCTTTAAAGATTGGTCCGGACGATTG
CGAAACCAGGGCCGGATCTG

Downstream 100 bases:

>100_bases
GTTCAGTTTTCCGCCGTGCGGGGTTGGTTGTTGTGTCGGTGGCGTGTCTTGGCGTGCCATCCATGGGCTTTTCCAAGACC
GATCAAGCGCAAACCACGCA

Product: nodulation protein T precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTPAHDNALQPNNKLHGKWWLSLIVVPLSACVAVTQSNVDISKLANRWHATLPHSGSTAQLVDWWNTFNDPALSELLRTA
EANSPTLESAVAEIEEARATLASSKADYFPSLTGSGSYDRSGTRGSKANRVAPSTTGTGELDASWELDFFGKTRNTVEAA
RQRVAEETADWYDARVTLAAEVADDYVQYKGCRQLQGIYAAELVSQQQTVKATEVSTASGLKSSSDLALIKASAASTSSS
LKSQVADCEVLIKSITELVAVDEDKVRDILNKSSSKIPRPAKLSVDAIPANVIRQRPDVNALEKEAAASLADVATAKADL
YPSFSLSGTLTASHSTSSGTSLPWSFGPAVSIPIFDGGSLRATVKYKEAAYKAAIASYKSGVLTAINAVETAMVNVDSTE
RQIGDAVVAAKNYRAYFKAIDTNWKAGGASVLDREDARRELQAAELTLVENQRDAVRDWIALYKAMGGGWTPNATGGEMA
SDVDAKGVKQ

Sequences:

>Translated_490_residues
MTPAHDNALQPNNKLHGKWWLSLIVVPLSACVAVTQSNVDISKLANRWHATLPHSGSTAQLVDWWNTFNDPALSELLRTA
EANSPTLESAVAEIEEARATLASSKADYFPSLTGSGSYDRSGTRGSKANRVAPSTTGTGELDASWELDFFGKTRNTVEAA
RQRVAEETADWYDARVTLAAEVADDYVQYKGCRQLQGIYAAELVSQQQTVKATEVSTASGLKSSSDLALIKASAASTSSS
LKSQVADCEVLIKSITELVAVDEDKVRDILNKSSSKIPRPAKLSVDAIPANVIRQRPDVNALEKEAAASLADVATAKADL
YPSFSLSGTLTASHSTSSGTSLPWSFGPAVSIPIFDGGSLRATVKYKEAAYKAAIASYKSGVLTAINAVETAMVNVDSTE
RQIGDAVVAAKNYRAYFKAIDTNWKAGGASVLDREDARRELQAAELTLVENQRDAVRDWIALYKAMGGGWTPNATGGEMA
SDVDAKGVKQ
>Mature_489_residues
TPAHDNALQPNNKLHGKWWLSLIVVPLSACVAVTQSNVDISKLANRWHATLPHSGSTAQLVDWWNTFNDPALSELLRTAE
ANSPTLESAVAEIEEARATLASSKADYFPSLTGSGSYDRSGTRGSKANRVAPSTTGTGELDASWELDFFGKTRNTVEAAR
QRVAEETADWYDARVTLAAEVADDYVQYKGCRQLQGIYAAELVSQQQTVKATEVSTASGLKSSSDLALIKASAASTSSSL
KSQVADCEVLIKSITELVAVDEDKVRDILNKSSSKIPRPAKLSVDAIPANVIRQRPDVNALEKEAAASLADVATAKADLY
PSFSLSGTLTASHSTSSGTSLPWSFGPAVSIPIFDGGSLRATVKYKEAAYKAAIASYKSGVLTAINAVETAMVNVDSTER
QIGDAVVAAKNYRAYFKAIDTNWKAGGASVLDREDARRELQAAELTLVENQRDAVRDWIALYKAMGGGWTPNATGGEMAS
DVDAKGVKQ

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=471, Percent_Identity=29.0870488322718, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI2367348, Length=429, Percent_Identity=26.1072261072261, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52258; Mature: 52126

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPAHDNALQPNNKLHGKWWLSLIVVPLSACVAVTQSNVDISKLANRWHATLPHSGSTAQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHH
LVDWWNTFNDPALSELLRTAEANSPTLESAVAEIEEARATLASSKADYFPSLTGSGSYDR
HHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SGTRGSKANRVAPSTTGTGELDASWELDFFGKTRNTVEAARQRVAEETADWYDARVTLAA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEHH
EVADDYVQYKGCRQLQGIYAAELVSQQQTVKATEVSTASGLKSSSDLALIKASAASTSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
LKSQVADCEVLIKSITELVAVDEDKVRDILNKSSSKIPRPAKLSVDAIPANVIRQRPDVN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHCCCCCC
ALEKEAAASLADVATAKADLYPSFSLSGTLTASHSTSSGTSLPWSFGPAVSIPIFDGGSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCE
RATVKYKEAAYKAAIASYKSGVLTAINAVETAMVNVDSTERQIGDAVVAAKNYRAYFKAI
EEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
DTNWKAGGASVLDREDARRELQAAELTLVENQRDAVRDWIALYKAMGGGWTPNATGGEMA
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
SDVDAKGVKQ
CCCCCCCCCC
>Mature Secondary Structure 
TPAHDNALQPNNKLHGKWWLSLIVVPLSACVAVTQSNVDISKLANRWHATLPHSGSTAQ
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHH
LVDWWNTFNDPALSELLRTAEANSPTLESAVAEIEEARATLASSKADYFPSLTGSGSYDR
HHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SGTRGSKANRVAPSTTGTGELDASWELDFFGKTRNTVEAARQRVAEETADWYDARVTLAA
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEEEHH
EVADDYVQYKGCRQLQGIYAAELVSQQQTVKATEVSTASGLKSSSDLALIKASAASTSSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHH
LKSQVADCEVLIKSITELVAVDEDKVRDILNKSSSKIPRPAKLSVDAIPANVIRQRPDVN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHCCCCCC
ALEKEAAASLADVATAKADLYPSFSLSGTLTASHSTSSGTSLPWSFGPAVSIPIFDGGSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCE
RATVKYKEAAYKAAIASYKSGVLTAINAVETAMVNVDSTERQIGDAVVAAKNYRAYFKAI
EEEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
DTNWKAGGASVLDREDARRELQAAELTLVENQRDAVRDWIALYKAMGGGWTPNATGGEMA
CCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
SDVDAKGVKQ
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2338917; 2622339 [H]