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The map label for this gene is rbsK [H]

Identifier: 222102778

GI number: 222102778

Start: 437466

End: 438362

Strand: Reverse

Name: rbsK [H]

Synonym: Avi_7479

Alternate gene names: 222102778

Gene position: 438362-437466 (Counterclockwise)

Preceding gene: 222102781

Following gene: 222102770

Centisome position: 69.39

GC content: 60.65

Gene sequence:

>897_bases
ATGCGTGCCTGGGTAATCGGTAATGTCGCAATCGATGAAATCATGTCCGTACCGACCATGCCAGAGGCCGGCGCGTCGAT
TTTTGGCCAGCAGCAAAGCACGGATCTGGGTGGCAAAGGCGCCAACCAGGCGATTGTTCTGGGCCGCGCCGGTTTGGACA
CCACGCTGATTGCCGCTGTCGGCAACGACCTTCGCGGCTCGATGATCCGGCAGAGCCTGTCGCTGGAGCCGATCGATAGC
CGCTTGATCGAGCTTGTCGATAAAGCCAGCGATATCTCGATGATCTTCACCACGCCGGATGGCGAAAATGCCATCATCAC
CACAACAGACTGTGCCACCAGCGTCCGGCCTGAGCATGTTACCAGTGTCTTACAGACGGCAAAACCCGGCGATCTGGCCA
TTCTCCAAGGCAATCTCACCGATGACACCACGGCTGCCCTCCTCCACGAGGCCAAACGCTGCGGCATGATCACCGCCTTT
AACCCATCACCGCTGCGGCCCGGCTTTGCCGCCCTTTGGTCGCTGATCGACATTGCCTTTTTGAACCAGGGCGAAGCCGA
TAAGCTGACAGGTGAAAGCGGCGAAGCCGCCACCCAATGCTTGCGTGATGCCGGTGTTGGTACCGTCATCATCACCCTTG
GCGGCAAGGGTGCAATCTTGGCGGATCGCACCGGCACCACCACAATCCCAGCCGTTCCATCCGTTGCTGTTGACACCACA
GGCGCAGGCGACACGTTCATGGCGGTTGCGCTGGCATCCAGCAGTTTGCGCCATGTCATGCCCGATGGCCTGGCGCTGCG
CCACGCAGCACAGGCCGCCAGCATCACCGTCAGTCGCCGGGGAACCCGGTCTGCGTTTCCATCACAGACCGAGTTGGCCG
CGATCTTCGCCACGTGA

Upstream 100 bases:

>100_bases
GCGCCCGAAAATTTCTCGCATAGTGCTTGATGTGTTGTCGGATATATCCAGCATTTCTCATTTCCTTTTGAAAGCCTGCC
ATGCGTGTTGAAAGTCTGTG

Downstream 100 bases:

>100_bases
GAGCATCACCGCGCTTGCGTCATCCAGCCCAGAATGTTCTTCCACAGCTTGCCATAGCCTTCCCATTCACAAAATGCAGG
CGAGAGCCAATGGGGTCCGA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MRAWVIGNVAIDEIMSVPTMPEAGASIFGQQQSTDLGGKGANQAIVLGRAGLDTTLIAAVGNDLRGSMIRQSLSLEPIDS
RLIELVDKASDISMIFTTPDGENAIITTTDCATSVRPEHVTSVLQTAKPGDLAILQGNLTDDTTAALLHEAKRCGMITAF
NPSPLRPGFAALWSLIDIAFLNQGEADKLTGESGEAATQCLRDAGVGTVIITLGGKGAILADRTGTTTIPAVPSVAVDTT
GAGDTFMAVALASSSLRHVMPDGLALRHAAQAASITVSRRGTRSAFPSQTELAAIFAT

Sequences:

>Translated_298_residues
MRAWVIGNVAIDEIMSVPTMPEAGASIFGQQQSTDLGGKGANQAIVLGRAGLDTTLIAAVGNDLRGSMIRQSLSLEPIDS
RLIELVDKASDISMIFTTPDGENAIITTTDCATSVRPEHVTSVLQTAKPGDLAILQGNLTDDTTAALLHEAKRCGMITAF
NPSPLRPGFAALWSLIDIAFLNQGEADKLTGESGEAATQCLRDAGVGTVIITLGGKGAILADRTGTTTIPAVPSVAVDTT
GAGDTFMAVALASSSLRHVMPDGLALRHAAQAASITVSRRGTRSAFPSQTELAAIFAT
>Mature_298_residues
MRAWVIGNVAIDEIMSVPTMPEAGASIFGQQQSTDLGGKGANQAIVLGRAGLDTTLIAAVGNDLRGSMIRQSLSLEPIDS
RLIELVDKASDISMIFTTPDGENAIITTTDCATSVRPEHVTSVLQTAKPGDLAILQGNLTDDTTAALLHEAKRCGMITAF
NPSPLRPGFAALWSLIDIAFLNQGEADKLTGESGEAATQCLRDAGVGTVIITLGGKGAILADRTGTTTIPAVPSVAVDTT
GAGDTFMAVALASSSLRHVMPDGLALRHAAQAASITVSRRGTRSAFPSQTELAAIFAT

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=301, Percent_Identity=29.2358803986711, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1790193, Length=299, Percent_Identity=29.7658862876254, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081971, Length=254, Percent_Identity=28.740157480315, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=299, Percent_Identity=30.4347826086957, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319884, Length=322, Percent_Identity=23.6024844720497, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI20128807, Length=301, Percent_Identity=32.2259136212625, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=28.3828382838284, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30754; Mature: 30754

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAWVIGNVAIDEIMSVPTMPEAGASIFGQQQSTDLGGKGANQAIVLGRAGLDTTLIAAV
CCEEEECCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEHHHH
GNDLRGSMIRQSLSLEPIDSRLIELVDKASDISMIFTTPDGENAIITTTDCATSVRPEHV
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHH
TSVLQTAKPGDLAILQGNLTDDTTAALLHEAKRCGMITAFNPSPLRPGFAALWSLIDIAF
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHH
LNQGEADKLTGESGEAATQCLRDAGVGTVIITLGGKGAILADRTGTTTIPAVPSVAVDTT
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEECCCCCCEEEECC
GAGDTFMAVALASSSLRHVMPDGLALRHAAQAASITVSRRGTRSAFPSQTELAAIFAT
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MRAWVIGNVAIDEIMSVPTMPEAGASIFGQQQSTDLGGKGANQAIVLGRAGLDTTLIAAV
CCEEEECCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEHHHH
GNDLRGSMIRQSLSLEPIDSRLIELVDKASDISMIFTTPDGENAIITTTDCATSVRPEHV
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCCCCCCHHHH
TSVLQTAKPGDLAILQGNLTDDTTAALLHEAKRCGMITAFNPSPLRPGFAALWSLIDIAF
HHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHH
LNQGEADKLTGESGEAATQCLRDAGVGTVIITLGGKGAILADRTGTTTIPAVPSVAVDTT
CCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEECCCCCCEEEECC
GAGDTFMAVALASSSLRHVMPDGLALRHAAQAASITVSRRGTRSAFPSQTELAAIFAT
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]