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The map label for this gene is mhpR [H]

Identifier: 222102729

GI number: 222102729

Start: 382376

End: 383233

Strand: Reverse

Name: mhpR [H]

Synonym: Avi_7409

Alternate gene names: 222102729

Gene position: 383233-382376 (Counterclockwise)

Preceding gene: 222102734

Following gene: 222102721

Centisome position: 60.66

GC content: 52.21

Gene sequence:

>858_bases
ATGTCAGAAAACATCAGAGCTTTGTCCCGTGGACTCAATGTGCTTGAGTTTCTCAGCGAGACCGGTGGCGCGACCAGACA
GGCCACCGTTGCCCATTTCGGGCTCTCGCGACCCACGATCTATCGTTTACTCGGTACCCTTGAAAAAAGTGGCCTTATCT
CGCTTGGTGACGATGGTGTCTATCGACCGACCATTGCCACGCGCGCCCTCAAGGAAGGGCTGACGGATGACGTATGGGCG
CTCTGGGCGGCTGAGCCCATTCTGCTCGAGTTACAAAAGGAAGTGGTCTGGACCAGTGAGATCACCACCTTCGATGCTTA
CAGCTGTACAATGCTCAAGCGTGATACAACCCACTCACTAAACCCCTATCATATCAACCTGCTGGATTTTGATGACAACC
ACCGATCAATGCTGACAAGTGCATGCGGTCTTGCCTATTTGGCCTTCTGCCCCCAACAACAGCGGGCGCAGATTCTCGAG
CATCTCGGACATTTTGGTGATCGGACCCAGTCCGATAGTCAGCGGCCCGATAGTCAGCGGGGTGCCGGTGCCCACACTCG
AAATTTGATCAACAAAGTTATTAGCGACGGGTACGCTGTCGAGCAACGAAACTCGTATCCACTGATCGCGGCCATCGCCG
TTCCCATTCGTTATGACAATCGTGTGCTTGCATGTCTGAGCATTGTTTGGCTTCCGCGTGCTGTAAAGCTGCAGGATGGC
ATCACTCAGTTTTTACCGGCTCTCAAACGAGCACAATCTTTCATTGAACAGAAGCTCCTGGACGATGCCTCAATTGAGTA
TGATACGAATTTTACCGCCAAATATGTCCATCATGGGCAACAGCACGAGCTGATTTAA

Upstream 100 bases:

>100_bases
CCACAAAAGTTGCCGTTATCGGCACCGTCCGCTCTTGGGCGCAAAGCATATTGACAGACGTTAAAATGAGTGGCCATTTT
GATGTGGGAGGAATAACAAC

Downstream 100 bases:

>100_bases
TCGAAATCCTATCCTTTTTTTGATTGACGTTTTTAAAGTTTCGGGCAGCAATCGGGGCAAGACACAAAACCGAAATCGTC
GTCCGGCGGTAAACCGGACG

Product: Transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSENIRALSRGLNVLEFLSETGGATRQATVAHFGLSRPTIYRLLGTLEKSGLISLGDDGVYRPTIATRALKEGLTDDVWA
LWAAEPILLELQKEVVWTSEITTFDAYSCTMLKRDTTHSLNPYHINLLDFDDNHRSMLTSACGLAYLAFCPQQQRAQILE
HLGHFGDRTQSDSQRPDSQRGAGAHTRNLINKVISDGYAVEQRNSYPLIAAIAVPIRYDNRVLACLSIVWLPRAVKLQDG
ITQFLPALKRAQSFIEQKLLDDASIEYDTNFTAKYVHHGQQHELI

Sequences:

>Translated_285_residues
MSENIRALSRGLNVLEFLSETGGATRQATVAHFGLSRPTIYRLLGTLEKSGLISLGDDGVYRPTIATRALKEGLTDDVWA
LWAAEPILLELQKEVVWTSEITTFDAYSCTMLKRDTTHSLNPYHINLLDFDDNHRSMLTSACGLAYLAFCPQQQRAQILE
HLGHFGDRTQSDSQRPDSQRGAGAHTRNLINKVISDGYAVEQRNSYPLIAAIAVPIRYDNRVLACLSIVWLPRAVKLQDG
ITQFLPALKRAQSFIEQKLLDDASIEYDTNFTAKYVHHGQQHELI
>Mature_284_residues
SENIRALSRGLNVLEFLSETGGATRQATVAHFGLSRPTIYRLLGTLEKSGLISLGDDGVYRPTIATRALKEGLTDDVWAL
WAAEPILLELQKEVVWTSEITTFDAYSCTMLKRDTTHSLNPYHINLLDFDDNHRSMLTSACGLAYLAFCPQQQRAQILEH
LGHFGDRTQSDSQRPDSQRGAGAHTRNLINKVISDGYAVEQRNSYPLIAAIAVPIRYDNRVLACLSIVWLPRAVKLQDGI
TQFLPALKRAQSFIEQKLLDDASIEYDTNFTAKYVHHGQQHELI

Specific function: Activator of the mhpRABCDEF operon coding for components of the 3-hydroxyphenylpropionate degradation pathway [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI145693096, Length=267, Percent_Identity=33.7078651685393, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31954; Mature: 31822

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENIRALSRGLNVLEFLSETGGATRQATVAHFGLSRPTIYRLLGTLEKSGLISLGDDGV
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCC
YRPTIATRALKEGLTDDVWALWAAEPILLELQKEVVWTSEITTFDAYSCTMLKRDTTHSL
CCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCC
NPYHINLLDFDDNHRSMLTSACGLAYLAFCPQQQRAQILEHLGHFGDRTQSDSQRPDSQR
CCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GAGAHTRNLINKVISDGYAVEQRNSYPLIAAIAVPIRYDNRVLACLSIVWLPRAVKLQDG
CCCHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCHHHHHHH
ITQFLPALKRAQSFIEQKLLDDASIEYDTNFTAKYVHHGQQHELI
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
SENIRALSRGLNVLEFLSETGGATRQATVAHFGLSRPTIYRLLGTLEKSGLISLGDDGV
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCC
YRPTIATRALKEGLTDDVWALWAAEPILLELQKEVVWTSEITTFDAYSCTMLKRDTTHSL
CCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCEECCCEEEEEECCCCCCC
NPYHINLLDFDDNHRSMLTSACGLAYLAFCPQQQRAQILEHLGHFGDRTQSDSQRPDSQR
CCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GAGAHTRNLINKVISDGYAVEQRNSYPLIAAIAVPIRYDNRVLACLSIVWLPRAVKLQDG
CCCHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHCCCHHHHHHH
ITQFLPALKRAQSFIEQKLLDDASIEYDTNFTAKYVHHGQQHELI
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]