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The map label for this gene is namA [H]

Identifier: 222102714

GI number: 222102714

Start: 364439

End: 365530

Strand: Direct

Name: namA [H]

Synonym: Avi_7390

Alternate gene names: 222102714

Gene position: 364439-365530 (Clockwise)

Preceding gene: 222102712

Following gene: 222102715

Centisome position: 57.68

GC content: 58.15

Gene sequence:

>1092_bases
ATGTCATCCTTGTTTACCCCTTTCACACTCAAAGGCATAACACTGCGAAATCGCATTGCGGTATCGCCGATGTGCCAGTA
TTCGGCCGAGGACGGCATCATCAATGACTGGCATCACGTCCATCTGGCTGGACTCGCGCGCGGCGGGGCAGGTTTGGTGG
TCGCTGAGGCGACAGCGGTATCGCCGGAAGGCCGGATCACTCCCGGATGCGCAGGCATCTGGAACGATGAGCAGATTGAG
CCTTGGAAAAAAGCGGTGCATTTGATGAAGGCGGCAGGTGCCGTTCCCGGGATTCAGATCGGACACGCGGGCCGCAAAGC
GAGCGCCAATCGTCCATGGGAGGGAGACGACCATATTTCCGGGTCTGACCCGCGTGGCTGGGAAACGCTGGCACCATCCG
CCATTGCGTTCGGAGCAAATCTTGGCAAGGTGCCGCAGGCCATGACCCTTGCCGATATCGAGCGTATCACGGCAGACTTT
GTCTCTGCGGCGAAGCGGGCGCTGGCCGCTGGCTTTGAATGGCTTGAGCTTCACTTTGCTCATGGCTATCTCGGACAAAG
CTTCTTTTCGACCTGGTCTAATAAGCGCACAGACAATTATGGCGGTGACTTTGACGGACGAGCCAGATTTCTGCTCGAAA
CGCTCGCTGCTGTTCGCGATGTCTGGCCCGAACATTTACCGCTTGCCGCTCGCTTTGGCGTGACCGAATTCGACGGTTCG
AACGACCTGGAAGAGGGGATCGAAATGGTTCGCCGCTTCAAGGCTGGCGGCCTCGACATTATTGATGTCAGCATTGGCTT
CTCCACACCGACCGCGAATATTCCGTGGGGGCCTGCTTTCATGGGGCCGATCGCCCAACGGGTACGGCGTGAGGTTGGAC
TTCCCGCCACCACGAGCTGGTTCATCAGCGAGCCAAAGCAGGCCGATGCACTGATCGCAGACGATTTTGTAGATATGGTG
TCGCTTGGCCGCCCGCTGCTTGCCAACAGCCATTGGCCTTATCAAGCGGCGCTTGAGCTAGGTATCGACAAGCCGTCCTG
GACACTTCCCGCACCATATGCTCATTGGCTGGAACGCTACAGAACGGCCTGA

Upstream 100 bases:

>100_bases
ATGATTCATTCTAGCATCACAAGGTGTTGTTGCAAAGTTCGATTGTAATCGAACTATCGAAAATATATATGTGCATTTAT
AACGATCAATTGGAGTCTCC

Downstream 100 bases:

>100_bases
ATCTGAACAGACCGTCGCGACAGAATAACCACCGCGATTAAGGAAACCGCGGTGGTTACAGTTTGTAATCTCTGCAAAAA
ATGGCGCGATAGAAAAGAGC

Product: xenobiotic reductase A

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSSLFTPFTLKGITLRNRIAVSPMCQYSAEDGIINDWHHVHLAGLARGGAGLVVAEATAVSPEGRITPGCAGIWNDEQIE
PWKKAVHLMKAAGAVPGIQIGHAGRKASANRPWEGDDHISGSDPRGWETLAPSAIAFGANLGKVPQAMTLADIERITADF
VSAAKRALAAGFEWLELHFAHGYLGQSFFSTWSNKRTDNYGGDFDGRARFLLETLAAVRDVWPEHLPLAARFGVTEFDGS
NDLEEGIEMVRRFKAGGLDIIDVSIGFSTPTANIPWGPAFMGPIAQRVRREVGLPATTSWFISEPKQADALIADDFVDMV
SLGRPLLANSHWPYQAALELGIDKPSWTLPAPYAHWLERYRTA

Sequences:

>Translated_363_residues
MSSLFTPFTLKGITLRNRIAVSPMCQYSAEDGIINDWHHVHLAGLARGGAGLVVAEATAVSPEGRITPGCAGIWNDEQIE
PWKKAVHLMKAAGAVPGIQIGHAGRKASANRPWEGDDHISGSDPRGWETLAPSAIAFGANLGKVPQAMTLADIERITADF
VSAAKRALAAGFEWLELHFAHGYLGQSFFSTWSNKRTDNYGGDFDGRARFLLETLAAVRDVWPEHLPLAARFGVTEFDGS
NDLEEGIEMVRRFKAGGLDIIDVSIGFSTPTANIPWGPAFMGPIAQRVRREVGLPATTSWFISEPKQADALIADDFVDMV
SLGRPLLANSHWPYQAALELGIDKPSWTLPAPYAHWLERYRTA
>Mature_362_residues
SSLFTPFTLKGITLRNRIAVSPMCQYSAEDGIINDWHHVHLAGLARGGAGLVVAEATAVSPEGRITPGCAGIWNDEQIEP
WKKAVHLMKAAGAVPGIQIGHAGRKASANRPWEGDDHISGSDPRGWETLAPSAIAFGANLGKVPQAMTLADIERITADFV
SAAKRALAAGFEWLELHFAHGYLGQSFFSTWSNKRTDNYGGDFDGRARFLLETLAAVRDVWPEHLPLAARFGVTEFDGSN
DLEEGIEMVRRFKAGGLDIIDVSIGFSTPTANIPWGPAFMGPIAQRVRREVGLPATTSWFISEPKQADALIADDFVDMVS
LGRPLLANSHWPYQAALELGIDKPSWTLPAPYAHWLERYRTA

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=361, Percent_Identity=29.0858725761773, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789463, Length=339, Percent_Identity=27.1386430678466, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17565138, Length=328, Percent_Identity=27.1341463414634, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=304, Percent_Identity=27.9605263157895, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17564188, Length=307, Percent_Identity=27.3615635179153, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=354, Percent_Identity=25.7062146892655, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=307, Percent_Identity=26.3843648208469, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=261, Percent_Identity=27.9693486590038, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=245, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=31.1965811965812, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=396, Percent_Identity=29.5454545454545, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39524; Mature: 39393

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLFTPFTLKGITLRNRIAVSPMCQYSAEDGIINDWHHVHLAGLARGGAGLVVAEATAV
CCCCCCCEEEECEEECCCEEECHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEE
SPEGRITPGCAGIWNDEQIEPWKKAVHLMKAAGAVPGIQIGHAGRKASANRPWEGDDHIS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
GSDPRGWETLAPSAIAFGANLGKVPQAMTLADIERITADFVSAAKRALAAGFEWLELHFA
CCCCCCCHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HGYLGQSFFSTWSNKRTDNYGGDFDGRARFLLETLAAVRDVWPEHLPLAARFGVTEFDGS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCHHHHCCCEECCCC
NDLEEGIEMVRRFKAGGLDIIDVSIGFSTPTANIPWGPAFMGPIAQRVRREVGLPATTSW
CCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
FISEPKQADALIADDFVDMVSLGRPLLANSHWPYQAALELGIDKPSWTLPAPYAHWLERY
HHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
RTA
CCC
>Mature Secondary Structure 
SSLFTPFTLKGITLRNRIAVSPMCQYSAEDGIINDWHHVHLAGLARGGAGLVVAEATAV
CCCCCCEEEECEEECCCEEECHHHHCCCCCCCCCCCCEEEEEEECCCCCCEEEEEEEEE
SPEGRITPGCAGIWNDEQIEPWKKAVHLMKAAGAVPGIQIGHAGRKASANRPWEGDDHIS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCC
GSDPRGWETLAPSAIAFGANLGKVPQAMTLADIERITADFVSAAKRALAAGFEWLELHFA
CCCCCCCHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
HGYLGQSFFSTWSNKRTDNYGGDFDGRARFLLETLAAVRDVWPEHLPLAARFGVTEFDGS
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCHHHHCCCEECCCC
NDLEEGIEMVRRFKAGGLDIIDVSIGFSTPTANIPWGPAFMGPIAQRVRREVGLPATTSW
CCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHH
FISEPKQADALIADDFVDMVSLGRPLLANSHWPYQAALELGIDKPSWTLPAPYAHWLERY
HHCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
RTA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA