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The map label for this gene is rbsK [H]

Identifier: 222102696

GI number: 222102696

Start: 344325

End: 345224

Strand: Direct

Name: rbsK [H]

Synonym: Avi_7369

Alternate gene names: 222102696

Gene position: 344325-345224 (Clockwise)

Preceding gene: 222102695

Following gene: 222102698

Centisome position: 54.5

GC content: 61.22

Gene sequence:

>900_bases
ATGACATTCTCGCCTATCGTCACCGTTTTCGGCAGCCTGCATTATGATATCGCGGTCTTCGGTCCAGACCGGCCACGTCA
GGGAGAAACTGTTGCAGGCACGTCCTGGCACCCCAAAAGCGGCGGCAAGGGTGGCAATCAGGCTGTCTCGGCAGCACAGG
CTGGCGTCTCGACATTCATGATCGGCGCAGTTGCCGACGACGAATTCGGACGGTTTCTGTTGGAAAATCTTAAACGCCGA
CAGGTTGATGATCGCTTCGTGCGGCGCGACGCCGTGGCGTCTACCGGCCACGCCACCGGCATGAGCGTGGCGATTTTCGA
CGCGCAGGGCGATTACGGTGCCGTTATTGTGTCCGGCGCTAACCTGACGCTTGGCGATCAGGATGTTGCAGCCGCAGCCG
ATCTGCTGGGCCGGACAACGGTTCTTGTGCTACAGAACGAGATCCCCGACGCCGCCAATGTCGCCGCAGCAAGGGCCGTC
CGGCAGGCTGGCGGCCGAGTCCTGATCAATGCCGCACCGGCGCGCGCCTTGTCAGCCGACCTTCAGAACCTGATCGACAT
CATCGTCGTCAACGCCATCGAGGCTGAAATGCTGGCGGGTGTCCCGGTTGTCGAAACGCTCGATGGCGCATTGGAAGCGG
CAAGGAGGCTGTTGGCGAACTTCCCGGACGTTGTGGTCACCGCAGGCGGCGCGGGTGTCGCCTACGCAAGTCGAGGCGGA
GACGAAATTGTCCTGCCTGCCGTGAAGGTGAAAGTGGAAAGCACGCACGGAGCCGGCGACATGTTCATCGGCGTGATGGC
CGCAACCCTCGCCACGGGAAAATCGATGCGCGACGCACTTTCACTGGCAAATATCGAAGCCGCAAAACTGGTTGCGACAC
CAGAGGCTGAACGCCTTTAG

Upstream 100 bases:

>100_bases
CCATTTTCGTCGCCGTCGCCCAGCGCGACTATCAGGCCGCCGAGCGCAATCTCGACCGCACCATGTCCGCCGTCACCTCT
AAACGTAGAGATCGCCTTCC

Downstream 100 bases:

>100_bases
AGTTTGTCAGGGAAAAGGGAAAACCGATTTTTCCGAAAACACAAACGAAAACAAGAGAATTTAGAGTCTGTCTGGTTCAA
TCTGAACGTGACAGACTCTA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTFSPIVTVFGSLHYDIAVFGPDRPRQGETVAGTSWHPKSGGKGGNQAVSAAQAGVSTFMIGAVADDEFGRFLLENLKRR
QVDDRFVRRDAVASTGHATGMSVAIFDAQGDYGAVIVSGANLTLGDQDVAAAADLLGRTTVLVLQNEIPDAANVAAARAV
RQAGGRVLINAAPARALSADLQNLIDIIVVNAIEAEMLAGVPVVETLDGALEAARRLLANFPDVVVTAGGAGVAYASRGG
DEIVLPAVKVKVESTHGAGDMFIGVMAATLATGKSMRDALSLANIEAAKLVATPEAERL

Sequences:

>Translated_299_residues
MTFSPIVTVFGSLHYDIAVFGPDRPRQGETVAGTSWHPKSGGKGGNQAVSAAQAGVSTFMIGAVADDEFGRFLLENLKRR
QVDDRFVRRDAVASTGHATGMSVAIFDAQGDYGAVIVSGANLTLGDQDVAAAADLLGRTTVLVLQNEIPDAANVAAARAV
RQAGGRVLINAAPARALSADLQNLIDIIVVNAIEAEMLAGVPVVETLDGALEAARRLLANFPDVVVTAGGAGVAYASRGG
DEIVLPAVKVKVESTHGAGDMFIGVMAATLATGKSMRDALSLANIEAAKLVATPEAERL
>Mature_298_residues
TFSPIVTVFGSLHYDIAVFGPDRPRQGETVAGTSWHPKSGGKGGNQAVSAAQAGVSTFMIGAVADDEFGRFLLENLKRRQ
VDDRFVRRDAVASTGHATGMSVAIFDAQGDYGAVIVSGANLTLGDQDVAAAADLLGRTTVLVLQNEIPDAANVAAARAVR
QAGGRVLINAAPARALSADLQNLIDIIVVNAIEAEMLAGVPVVETLDGALEAARRLLANFPDVVVTAGGAGVAYASRGGD
EIVLPAVKVKVESTHGAGDMFIGVMAATLATGKSMRDALSLANIEAAKLVATPEAERL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=283, Percent_Identity=37.4558303886926, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1790193, Length=272, Percent_Identity=31.6176470588235, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17532905, Length=284, Percent_Identity=34.5070422535211, Blast_Score=128, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319884, Length=316, Percent_Identity=28.4810126582279, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20128807, Length=272, Percent_Identity=35.6617647058824, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24583886, Length=273, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30743; Mature: 30612

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSPIVTVFGSLHYDIAVFGPDRPRQGETVAGTSWHPKSGGKGGNQAVSAAQAGVSTFM
CCCCHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHCHHHEE
IGAVADDEFGRFLLENLKRRQVDDRFVRRDAVASTGHATGMSVAIFDAQGDYGAVIVSGA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEECC
NLTLGDQDVAAAADLLGRTTVLVLQNEIPDAANVAAARAVRQAGGRVLINAAPARALSAD
EEEECCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
LQNLIDIIVVNAIEAEMLAGVPVVETLDGALEAARRLLANFPDVVVTAGGAGVAYASRGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCC
DEIVLPAVKVKVESTHGAGDMFIGVMAATLATGKSMRDALSLANIEAAKLVATPEAERL
CEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHEEEECCCCCCC
>Mature Secondary Structure 
TFSPIVTVFGSLHYDIAVFGPDRPRQGETVAGTSWHPKSGGKGGNQAVSAAQAGVSTFM
CCCHHHHHHCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHCHHHEE
IGAVADDEFGRFLLENLKRRQVDDRFVRRDAVASTGHATGMSVAIFDAQGDYGAVIVSGA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEECC
NLTLGDQDVAAAADLLGRTTVLVLQNEIPDAANVAAARAVRQAGGRVLINAAPARALSAD
EEEECCHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
LQNLIDIIVVNAIEAEMLAGVPVVETLDGALEAARRLLANFPDVVVTAGGAGVAYASRGG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCC
DEIVLPAVKVKVESTHGAGDMFIGVMAATLATGKSMRDALSLANIEAAKLVATPEAERL
CEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]