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The map label for this gene is grsT [H]

Identifier: 222102640

GI number: 222102640

Start: 253238

End: 254032

Strand: Reverse

Name: grsT [H]

Synonym: Avi_7295

Alternate gene names: 222102640

Gene position: 254032-253238 (Counterclockwise)

Preceding gene: 222102641

Following gene: 222102639

Centisome position: 40.21

GC content: 59.75

Gene sequence:

>795_bases
ATGACGATAACGCCATCACGCCCCGTGCTTCTTTGCCTGCCGCCAGCAGGCACCGGGGCCGGGCTTTTCCGCAACTGGGT
ACAAACCGCGCCGAGCACGATGACGGTGCATCCGGTCGCACTGCCGGGCCGCGAAGCGCGCTATTGCGAACCGGCACCGA
GGTCAATTGACGCGCTTGCCGATCAACTGGCCGTTGAGCTTGAGCCTTATATCGGCGGGCGCTATGCGATTTTCGGCTAT
TCGATGGGTGCCCTCCTCGGCTATGAAATCGCCCGTCGCTTTTCAGCGGCAGGCTTGCCGATGCCGGAGGTGTTTTTCGC
GCTCGGTTGCAATGCGCCGGACCGCATGGTCTATGAGCGAGAGCCGTTCCACACGATGGAAGCCGACGCCTTTCGCCAAG
CGCTTATCGATCTCGGCGGAACAGATGCTGAAATCCTCAACAATCCCGAGGCAATGGAGCTTTTCGAACCGTTGCTGCGC
AATGATTTCAGAATATGCGAGACCTATACCCATGATGCGACGCGCGGCACGCTCGATTGTCCCGTCCATATTTTCCTCTC
CGATGGAGACGCCTTTGTAAACCGGCAGGCCGCCGCAGCCTGGTGTGATTTCGTGACCGGCGGCACGCGCCTGCATCCGG
TCGCGGGCGCGCATATGCTGGAGCGACCGGTACTTGACACGCTGCCCGCACGACTGGCAACTCTCTGGTTCGGAACTGGC
GAAAATCGCCTACAGCATCGGTCCGAAAAGTGGGAACCGGTTTTCGGAAAGTCCGATGCGAAAACAAGAATCTAG

Upstream 100 bases:

>100_bases
GCGTCCTTTTTGAGCACCCCGTCCTTGCCGACCTTGCGGCCTATATCGACAGCCTTCGCCCGCAAGTCCCCCCGGCCACA
GACCATATTGAGATTGACAT

Downstream 100 bases:

>100_bases
AGCATCGTGCCGATTCCAATTTTTGGTACGATGCTCTAAGGCGCGAGGGTTAAGCGATGATGGCGGCGATGGACATACCA
ACATCGGAGGAGGCAATGGT

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTITPSRPVLLCLPPAGTGAGLFRNWVQTAPSTMTVHPVALPGREARYCEPAPRSIDALADQLAVELEPYIGGRYAIFGY
SMGALLGYEIARRFSAAGLPMPEVFFALGCNAPDRMVYEREPFHTMEADAFRQALIDLGGTDAEILNNPEAMELFEPLLR
NDFRICETYTHDATRGTLDCPVHIFLSDGDAFVNRQAAAAWCDFVTGGTRLHPVAGAHMLERPVLDTLPARLATLWFGTG
ENRLQHRSEKWEPVFGKSDAKTRI

Sequences:

>Translated_264_residues
MTITPSRPVLLCLPPAGTGAGLFRNWVQTAPSTMTVHPVALPGREARYCEPAPRSIDALADQLAVELEPYIGGRYAIFGY
SMGALLGYEIARRFSAAGLPMPEVFFALGCNAPDRMVYEREPFHTMEADAFRQALIDLGGTDAEILNNPEAMELFEPLLR
NDFRICETYTHDATRGTLDCPVHIFLSDGDAFVNRQAAAAWCDFVTGGTRLHPVAGAHMLERPVLDTLPARLATLWFGTG
ENRLQHRSEKWEPVFGKSDAKTRI
>Mature_263_residues
TITPSRPVLLCLPPAGTGAGLFRNWVQTAPSTMTVHPVALPGREARYCEPAPRSIDALADQLAVELEPYIGGRYAIFGYS
MGALLGYEIARRFSAAGLPMPEVFFALGCNAPDRMVYEREPFHTMEADAFRQALIDLGGTDAEILNNPEAMELFEPLLRN
DFRICETYTHDATRGTLDCPVHIFLSDGDAFVNRQAAAAWCDFVTGGTRLHPVAGAHMLERPVLDTLPARLATLWFGTGE
NRLQHRSEKWEPVFGKSDAKTRI

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=213, Percent_Identity=26.2910798122066, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI8922871, Length=187, Percent_Identity=25.1336898395722, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 29138; Mature: 29006

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITPSRPVLLCLPPAGTGAGLFRNWVQTAPSTMTVHPVALPGREARYCEPAPRSIDALA
CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
DQLAVELEPYIGGRYAIFGYSMGALLGYEIARRFSAAGLPMPEVFFALGCNAPDRMVYER
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECC
EPFHTMEADAFRQALIDLGGTDAEILNNPEAMELFEPLLRNDFRICETYTHDATRGTLDC
CCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCC
PVHIFLSDGDAFVNRQAAAAWCDFVTGGTRLHPVAGAHMLERPVLDTLPARLATLWFGTG
CEEEEEECCHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENRLQHRSEKWEPVFGKSDAKTRI
HHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TITPSRPVLLCLPPAGTGAGLFRNWVQTAPSTMTVHPVALPGREARYCEPAPRSIDALA
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHH
DQLAVELEPYIGGRYAIFGYSMGALLGYEIARRFSAAGLPMPEVFFALGCNAPDRMVYER
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEECC
EPFHTMEADAFRQALIDLGGTDAEILNNPEAMELFEPLLRNDFRICETYTHDATRGTLDC
CCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHCCCCCCCCCCC
PVHIFLSDGDAFVNRQAAAAWCDFVTGGTRLHPVAGAHMLERPVLDTLPARLATLWFGTG
CEEEEEECCHHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ENRLQHRSEKWEPVFGKSDAKTRI
HHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]