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The map label for this gene is appC [H]

Identifier: 222102551

GI number: 222102551

Start: 149950

End: 150957

Strand: Direct

Name: appC [H]

Synonym: Avi_7183

Alternate gene names: 222102551

Gene position: 149950-150957 (Clockwise)

Preceding gene: 222102550

Following gene: 222102552

Centisome position: 23.73

GC content: 58.53

Gene sequence:

>1008_bases
ATGACAATTATCAATGCAACGACACCGCTCGCCGAGGCTACGCGCCAGCGTGAAGGGGAAAAGGCAAGCGTTGAAACGGC
CAAAGAGGCCAAAGCCCCCAAAGGCTGGCCCTATGTCCATGCACCCGACGCGCTGACAGCCCGCACCAGTCTGATACCAA
AACGGGGTCTGCGCCGTGAGGTCAAAATCTTTCTCACCAACCCCAATGCGTTGATTGGCGTGGCGTTTCTGGCCATTGTC
ATCATCACAGCGCTTCTGGCTCCCTTGCTTTATCCCGGCGATCCGCTGGAAATGGTGTCGCGGCCCTTCCTCTGGCCGGG
GCAGAACCCCGCCTATCCACTGGGAACCGATTCCATGGGGCGTGACGTGCTGGCGGGTATTGTGCACGGGGCACGGGTTT
CGCTCACAGTCGGCATTGCCGCAACCGTGATGGGGCTGACCATCGGCGTCACCATTGGTGCATTTGCAGGCTATTTCGGT
GGCGTGATCGATGATGTTCTCGTCAAGATCATCGAGATTTTCCAGACGCTTCCCAGCTTTGTGCTGCTGGTGGTGTTGGT
GGCCATTGCACAGCCGTCGATCACCACCGTGACCTTTGCCATCGGTATCATTACATGGCCGATGGTGGCCCGGCTGACCC
GCGCCGAATTCCGCGCAATCCGCGAAAAAGATTATGTGCTGGCCGCGCGAAGTCTCGGCTATGGCCATGCCCGCATCGTG
TTTGCAGAAATTCTGCCCAATGCCCTGCCGCCGATTATTGTCACATCGTCGGTGATGGTCGCGGGTGCGATTTTGATGGA
AGCGGCCCTGTCTTTCATGGGTCTGGGCGATCCAAACCGGGTCTCCTGGGGTTCGATGATTGGCTCTGGCCGTGAGGTGA
TCCGTACGGCCTGGTATCTCACGGCCCTGCCGGGGCTGGCCATTGTGTTTACGGTCATCTCCCTCAACCTGATCAGTGAC
GGGTTGAATGATGCGCTCAATCCCCGCTTTTCGGAGGAACGTCGATGA

Upstream 100 bases:

>100_bases
TTTTGGGAATTCTGCTGCTGTCATCCTTTTTGGTGATCATCATCAATGCTGCCGTGGATCTGTTTCAGGCCTGGCTCGAC
CCGCGGATTGGAGAAAGCCA

Downstream 100 bases:

>100_bases
GTGCTTTGATTGATGTTCGGGATTTTTCCGTTGGTTTCGGCAGCGCCCAGCCGGTCAAGGGCGTCAGCTTTTCGGTGGAA
CGCGGCGAAATGCTGGCGAT

Product: ABC transporter membrane spanning protein (oligopeptide)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MTIINATTPLAEATRQREGEKASVETAKEAKAPKGWPYVHAPDALTARTSLIPKRGLRREVKIFLTNPNALIGVAFLAIV
IITALLAPLLYPGDPLEMVSRPFLWPGQNPAYPLGTDSMGRDVLAGIVHGARVSLTVGIAATVMGLTIGVTIGAFAGYFG
GVIDDVLVKIIEIFQTLPSFVLLVVLVAIAQPSITTVTFAIGIITWPMVARLTRAEFRAIREKDYVLAARSLGYGHARIV
FAEILPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGREVIRTAWYLTALPGLAIVFTVISLNLISD
GLNDALNPRFSEERR

Sequences:

>Translated_335_residues
MTIINATTPLAEATRQREGEKASVETAKEAKAPKGWPYVHAPDALTARTSLIPKRGLRREVKIFLTNPNALIGVAFLAIV
IITALLAPLLYPGDPLEMVSRPFLWPGQNPAYPLGTDSMGRDVLAGIVHGARVSLTVGIAATVMGLTIGVTIGAFAGYFG
GVIDDVLVKIIEIFQTLPSFVLLVVLVAIAQPSITTVTFAIGIITWPMVARLTRAEFRAIREKDYVLAARSLGYGHARIV
FAEILPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGREVIRTAWYLTALPGLAIVFTVISLNLISD
GLNDALNPRFSEERR
>Mature_334_residues
TIINATTPLAEATRQREGEKASVETAKEAKAPKGWPYVHAPDALTARTSLIPKRGLRREVKIFLTNPNALIGVAFLAIVI
ITALLAPLLYPGDPLEMVSRPFLWPGQNPAYPLGTDSMGRDVLAGIVHGARVSLTVGIAATVMGLTIGVTIGAFAGYFGG
VIDDVLVKIIEIFQTLPSFVLLVVLVAIAQPSITTVTFAIGIITWPMVARLTRAEFRAIREKDYVLAARSLGYGHARIVF
AEILPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGREVIRTAWYLTALPGLAIVFTVISLNLISDG
LNDALNPRFSEERR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=287, Percent_Identity=39.3728222996516, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787760, Length=293, Percent_Identity=31.3993174061433, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1787054, Length=267, Percent_Identity=31.0861423220974, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787498, Length=271, Percent_Identity=32.4723247232472, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789889, Length=227, Percent_Identity=32.15859030837, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=30.7339449541284, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787549, Length=280, Percent_Identity=29.2857142857143, Blast_Score=108, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35867; Mature: 35736

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIINATTPLAEATRQREGEKASVETAKEAKAPKGWPYVHAPDALTARTSLIPKRGLRRE
CEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCEE
VKIFLTNPNALIGVAFLAIVIITALLAPLLYPGDPLEMVSRPFLWPGQNPAYPLGTDSMG
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCH
RDVLAGIVHGARVSLTVGIAATVMGLTIGVTIGAFAGYFGGVIDDVLVKIIEIFQTLPSF
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLVVLVAIAQPSITTVTFAIGIITWPMVARLTRAEFRAIREKDYVLAARSLGYGHARIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FAEILPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGREVIRTAWYL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHH
TALPGLAIVFTVISLNLISDGLNDALNPRFSEERR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TIINATTPLAEATRQREGEKASVETAKEAKAPKGWPYVHAPDALTARTSLIPKRGLRRE
EEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHCCCEE
VKIFLTNPNALIGVAFLAIVIITALLAPLLYPGDPLEMVSRPFLWPGQNPAYPLGTDSMG
EEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCH
RDVLAGIVHGARVSLTVGIAATVMGLTIGVTIGAFAGYFGGVIDDVLVKIIEIFQTLPSF
HHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLLVVLVAIAQPSITTVTFAIGIITWPMVARLTRAEFRAIREKDYVLAARSLGYGHARIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FAEILPNALPPIIVTSSVMVAGAILMEAALSFMGLGDPNRVSWGSMIGSGREVIRTAWYL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHH
TALPGLAIVFTVISLNLISDGLNDALNPRFSEERR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]