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The map label for this gene is gatA1 [H]

Identifier: 222102507

GI number: 222102507

Start: 102052

End: 103362

Strand: Reverse

Name: gatA1 [H]

Synonym: Avi_7127

Alternate gene names: 222102507

Gene position: 103362-102052 (Counterclockwise)

Preceding gene: 222102513

Following gene: 222102505

Centisome position: 16.36

GC content: 58.66

Gene sequence:

>1311_bases
ATGGGAATGACATTGCCTTATCAATTGGATGCCTGCACGCTCACGACCCTTACCCACGGTGGGCAACTTTCGGTCACCGA
CATCGCAACGTCGATCATCCGCCGCATTGAAGAGCGCGACAGTGCCGTTCGTGCCTATGCTCATTTCGATCCCACCCAGG
TTCTGGCTGCCGCGCAGATGCTGGATGCGGCACCCCATAAAGGGCCGCTGCATGGCGTACCCATTGCCATCAAGGACGTT
ATCAACACCAAGGATATGCCGACGCAGCACAATTCAGCCCGCTATCATGGACACCAGCCGGGAATGGATGCCGCCTGCGT
CGATACCCTGCGCCAAGCCGGAGCGTTGTTGATCGGGAAGACAGTCACGACCGAATTTGCCACAACAAACCGGGGAAGCG
TGACACGCAATCCGCACGATCTTGCGTGCACGCCGGGCGGGTCCTCCAGTGGATCGGCTGCAGCGGTTGCCGATTTTCAG
GCCACATTGGCGCTTGGCACCCAGACGGGAGGCTCCACCATACGACCCGCCTCTTTTTGCGGGATTTACGGGTTCAAACC
AACCTGGAATGCAATCAGCCGGGAAGGGTTGAAAATGTATTCCGCCACCTGCGATACCCTTGGCCTTTACGGCCGCTCGG
CTGATGATCTTGCCCTTCTGGCTGATGTTTTTGCGCTTGATGCAACGGAAACGGCGCTTGCCGATGACCTTGCCGGAAAG
CGGATTGGCGTGTGCCTCTCACCGGCCTGGCCAAAAGCAGAGCTTGCCACGCAACAGGCGATGAACACGGCAATCGATGC
CCTGAAACAGGCAGGGGCCGTGGTTTCGGATATTGCCTTGCCCGCGATGTTCGATGGCATTCTGGCCGCCCACCATATCA
TTTTGCGCCGTGAGGGGCGCTCGGCCTTCCTCAACGAGGCGAATGCGACACCCGACCTTCACGACGAACTGAAAGCCATT
GTTGAAAATCGCCAGGCCATCACCCCATCTCAGGCCCGCGATGCCTACCGGCTGGCCGATCAATGCCGTGCCGCCTTCGA
CGACATTGCTGCGTCCTATGATGTGATCCTCACGCCGAGTTCCACGGGCGAAGCGCCAAGGGGGATTGAGACAACCGGAG
ATGCGATATTCAATTCGATATGGACGTTGATGCAGGTGCCTGTCGTCAATGTTCCCGGCCTATACGGGCCAAATGGCAGG
CCCGTCGGAGTGTCCCTGACAGCGCAGCGCTATCAGGATCGCAAGGTGATCGCCTACGCTGATTTGTTGGGTGCAGCCCT
GCAAAACCGACAGAGCATGGCGGCAGAATAG

Upstream 100 bases:

>100_bases
CAAATGACCATTTCTCAGCCGCGTCGTGAGAAAATCTGCCGTGTCATAGAACAAGAGTAACGGTAACCTGCGCGCCACGA
TCGCACCCACCAAGAAGGAC

Downstream 100 bases:

>100_bases
CTGTCTTCCACAAAAAAGCGCCGTGCCGCATAAGCAAGGCACGGCGCTTACTGCATAATTCTTTAAACCGGAATCGGTTT
AAAGAGAAAATTATGCAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Glu-ADT subunit A 1 [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MGMTLPYQLDACTLTTLTHGGQLSVTDIATSIIRRIEERDSAVRAYAHFDPTQVLAAAQMLDAAPHKGPLHGVPIAIKDV
INTKDMPTQHNSARYHGHQPGMDAACVDTLRQAGALLIGKTVTTEFATTNRGSVTRNPHDLACTPGGSSSGSAAAVADFQ
ATLALGTQTGGSTIRPASFCGIYGFKPTWNAISREGLKMYSATCDTLGLYGRSADDLALLADVFALDATETALADDLAGK
RIGVCLSPAWPKAELATQQAMNTAIDALKQAGAVVSDIALPAMFDGILAAHHIILRREGRSAFLNEANATPDLHDELKAI
VENRQAITPSQARDAYRLADQCRAAFDDIAASYDVILTPSSTGEAPRGIETTGDAIFNSIWTLMQVPVVNVPGLYGPNGR
PVGVSLTAQRYQDRKVIAYADLLGAALQNRQSMAAE

Sequences:

>Translated_436_residues
MGMTLPYQLDACTLTTLTHGGQLSVTDIATSIIRRIEERDSAVRAYAHFDPTQVLAAAQMLDAAPHKGPLHGVPIAIKDV
INTKDMPTQHNSARYHGHQPGMDAACVDTLRQAGALLIGKTVTTEFATTNRGSVTRNPHDLACTPGGSSSGSAAAVADFQ
ATLALGTQTGGSTIRPASFCGIYGFKPTWNAISREGLKMYSATCDTLGLYGRSADDLALLADVFALDATETALADDLAGK
RIGVCLSPAWPKAELATQQAMNTAIDALKQAGAVVSDIALPAMFDGILAAHHIILRREGRSAFLNEANATPDLHDELKAI
VENRQAITPSQARDAYRLADQCRAAFDDIAASYDVILTPSSTGEAPRGIETTGDAIFNSIWTLMQVPVVNVPGLYGPNGR
PVGVSLTAQRYQDRKVIAYADLLGAALQNRQSMAAE
>Mature_435_residues
GMTLPYQLDACTLTTLTHGGQLSVTDIATSIIRRIEERDSAVRAYAHFDPTQVLAAAQMLDAAPHKGPLHGVPIAIKDVI
NTKDMPTQHNSARYHGHQPGMDAACVDTLRQAGALLIGKTVTTEFATTNRGSVTRNPHDLACTPGGSSSGSAAAVADFQA
TLALGTQTGGSTIRPASFCGIYGFKPTWNAISREGLKMYSATCDTLGLYGRSADDLALLADVFALDATETALADDLAGKR
IGVCLSPAWPKAELATQQAMNTAIDALKQAGAVVSDIALPAMFDGILAAHHIILRREGRSAFLNEANATPDLHDELKAIV
ENRQAITPSQARDAYRLADQCRAAFDDIAASYDVILTPSSTGEAPRGIETTGDAIFNSIWTLMQVPVVNVPGLYGPNGRP
VGVSLTAQRYQDRKVIAYADLLGAALQNRQSMAAE

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=493, Percent_Identity=25.9634888438134, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI195972892, Length=237, Percent_Identity=25.3164556962025, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=458, Percent_Identity=28.6026200873362, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17537465, Length=458, Percent_Identity=23.3624454148472, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990152, Length=131, Percent_Identity=36.6412213740458, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323950, Length=193, Percent_Identity=34.7150259067358, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319685, Length=390, Percent_Identity=23.0769230769231, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24648113, Length=474, Percent_Identity=25.5274261603376, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648435, Length=237, Percent_Identity=28.2700421940928, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648437, Length=237, Percent_Identity=28.2700421940928, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45550774, Length=237, Percent_Identity=28.2700421940928, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24644968, Length=485, Percent_Identity=22.0618556701031, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648441, Length=181, Percent_Identity=33.7016574585635, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648439, Length=181, Percent_Identity=33.7016574585635, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356731, Length=388, Percent_Identity=24.7422680412371, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24652985, Length=472, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI19922090, Length=472, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24652981, Length=472, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24652983, Length=472, Percent_Identity=25.4237288135593, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: NA

Molecular weight: Translated: 46114; Mature: 45982

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMTLPYQLDACTLTTLTHGGQLSVTDIATSIIRRIEERDSAVRAYAHFDPTQVLAAAQM
CCCCCCEEECCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LDAAPHKGPLHGVPIAIKDVINTKDMPTQHNSARYHGHQPGMDAACVDTLRQAGALLIGK
HHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
TVTTEFATTNRGSVTRNPHDLACTPGGSSSGSAAAVADFQATLALGTQTGGSTIRPASFC
CHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHHHHEEEEEECCCCCCCCCCHHHH
GIYGFKPTWNAISREGLKMYSATCDTLGLYGRSADDLALLADVFALDATETALADDLAGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
RIGVCLSPAWPKAELATQQAMNTAIDALKQAGAVVSDIALPAMFDGILAAHHIILRREGR
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCC
SAFLNEANATPDLHDELKAIVENRQAITPSQARDAYRLADQCRAAFDDIAASYDVILTPS
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
STGEAPRGIETTGDAIFNSIWTLMQVPVVNVPGLYGPNGRPVGVSLTAQRYQDRKVIAYA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEEHHH
DLLGAALQNRQSMAAE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GMTLPYQLDACTLTTLTHGGQLSVTDIATSIIRRIEERDSAVRAYAHFDPTQVLAAAQM
CCCCCEEECCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LDAAPHKGPLHGVPIAIKDVINTKDMPTQHNSARYHGHQPGMDAACVDTLRQAGALLIGK
HHCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
TVTTEFATTNRGSVTRNPHDLACTPGGSSSGSAAAVADFQATLALGTQTGGSTIRPASFC
CHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHHHHEEEEEECCCCCCCCCCHHHH
GIYGFKPTWNAISREGLKMYSATCDTLGLYGRSADDLALLADVFALDATETALADDLAGK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
RIGVCLSPAWPKAELATQQAMNTAIDALKQAGAVVSDIALPAMFDGILAAHHIILRREGR
EEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCC
SAFLNEANATPDLHDELKAIVENRQAITPSQARDAYRLADQCRAAFDDIAASYDVILTPS
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
STGEAPRGIETTGDAIFNSIWTLMQVPVVNVPGLYGPNGRPVGVSLTAQRYQDRKVIAYA
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEHHHCCCCEEEHHH
DLLGAALQNRQSMAAE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]