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The map label for this gene is smbA

Identifier: 222097270

GI number: 222097270

Start: 3572301

End: 3572798

Strand: Reverse

Name: smbA

Synonym: BCQ_3610

Alternate gene names: 222097270

Gene position: 3572798-3572301 (Counterclockwise)

Preceding gene: 222097271

Following gene: 222097269

Centisome position: 68.52

GC content: 38.96

Gene sequence:

>498_bases
ATGGGCATGTTAGCGACAGTTATGAATTCATTAGCTCTTCAAGATAGCTTGGAGAACATCGGGATTCAAACTCGCGTACA
AACTTCAATTGAAATGCGTCAAGTGGCAGAGCCTTACATTCGTCGTAAAGCAGTTCGTCACTTAGAGAAAAAACGTGTTG
TTATCTTTGCAGCAGGTACTGGTAACCCATACTTCTCTACAGATACAACGGCAGCATTACGTGCGGCGGAAATTGAAGCT
GACGTAATTTTAATGGCGAAAAACAATGTGGATGGCGTATATAATGCAGATCCATCTATTGACCCAACAGCTACGAAATA
CGAAACACTTACTTACTTAGATGTATTAAAAGAAGGTTTAGGTGTAATGGATTCTACAGCTTCTTCTCTATGTATGGATA
ATGATATTCCATTAATTGTATTCTCAGTTATGGAAAAAGGGAATATTAAACGTGCCGTGTTAGGCGAAAATATCGGAACA
GTTGTAAGGGGGAAATAA

Upstream 100 bases:

>100_bases
AGAACTAGATGTAGAGGTTGCTGTTGTTGTTGGCGGCGGTAACATTTGGCGTGGGAAAATTGGAAGTGAGATGGGCATGG
ATCGTGCAGGAGCGGATTAC

Downstream 100 bases:

>100_bases
ATATGGGACAACAAGTATTGAAGTCTGCAAATGAAAAAATGAAAAAGCGGTTGCTGCTTATTCACGCGAATTAGCAACAG
TTCGCGCTGGTCGTGCAAAC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MGMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEA
DVILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGT
VVRGK

Sequences:

>Translated_165_residues
MGMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEA
DVILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGT
VVRGK
>Mature_164_residues
GMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGTGNPYFSTDTTAALRAAEIEAD
VILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGLGVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGTV
VRGK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family

Homologues:

Organism=Escherichia coli, GI1786367, Length=162, Percent_Identity=48.7654320987654, Blast_Score=157, Evalue=4e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRH_BACAN (Q81WL0)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_846206.1
- RefSeq:   YP_020602.2
- RefSeq:   YP_029927.1
- ProteinModelPortal:   Q81WL0
- SMR:   Q81WL0
- EnsemblBacteria:   EBBACT00000009368
- EnsemblBacteria:   EBBACT00000014903
- EnsemblBacteria:   EBBACT00000024399
- GeneID:   1086816
- GeneID:   2819541
- GeneID:   2850619
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_3963
- KEGG:   bar:GBAA_3963
- KEGG:   bat:BAS3676
- TIGR:   BA_3963
- TIGR:   GBAA_3963
- GeneTree:   EBGT00050000001796
- HOGENOM:   HBG497552
- OMA:   RHMEKGR
- ProtClustDB:   PRK00358
- BioCyc:   BANT260799:BAS3676-MONOMER
- BioCyc:   BANT261594:GBAA3963-MONOMER
- BRENDA:   2.7.4.22
- GO:   GO:0005737
- HAMAP:   MF_01220_B
- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF005650
- TIGRFAMs:   TIGR02075

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.4.22

Molecular weight: Translated: 17983; Mature: 17852

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: BINDING 54-54 BINDING 55-55 BINDING 59-59 BINDING 74-74 BINDING 163-163 BINDING 169-169 BINDING 172-172

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGT
CCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
GNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGL
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHC
GVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGTVVRGK
CCHHCCHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCEEEECC
>Mature Secondary Structure 
GMLATVMNSLALQDSLENIGIQTRVQTSIEMRQVAEPYIRRKAVRHLEKKRVVIFAAGT
CHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECC
GNPYFSTDTTAALRAAEIEADVILMAKNNVDGVYNADPSIDPTATKYETLTYLDVLKEGL
CCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHC
GVMDSTASSLCMDNDIPLIVFSVMEKGNIKRAVLGENIGTVVRGK
CCHHCCHHHHHCCCCCCEEEEEECCCCCCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629