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The map label for this gene is ymfH [H]

Identifier: 222097233

GI number: 222097233

Start: 3528702

End: 3529988

Strand: Reverse

Name: ymfH [H]

Synonym: BCQ_3573

Alternate gene names: 222097233

Gene position: 3529988-3528702 (Counterclockwise)

Preceding gene: 222097234

Following gene: 222097232

Centisome position: 67.7

GC content: 32.4

Gene sequence:

>1287_bases
ATGGAGAAAATTGTTTATGAGCAATTAAAAGAGACACTCTATTATGAAAAACTTCCTAATGGATTAGATGTATATATTTT
ACCGAAGCAAGGATTTAATAAAACATTTGCAACGTTTACGACAAAATATGGTTCTGTGGATAATACATTCGTACCACTAG
GTAAAGAAGAAATGATTCGTGTGCCGGATGGGATTGCTCATTTTCTTGAGCATAAACTATTTGAAAAAGAAGATCACGAT
GCCTTCCAATTGTTTAGTAAACAAGGGGCATCGGCAAATGCTTTTACATCATTCACAAGAACAGCTTACCTTTTTTCATG
TACATCAAATGTAGAACAAAATTTAAATACATTGTTAAATTTCGTACAAGAGCCTTACTTTTCTGAAAAAACAGTTGAAA
AAGAGAAAGGTATTATTGGGCAAGAAATTCAAATGTATCAAGATAATCCAGATTGGCGCTTATATTTTGGGTTAATTGAT
AGCTTGTTTGTAAAGCACCCGATTAAAATTGATATTGCGGGTACAATCGAGTCTATTAGTAAAATTACGAAAGATCTACT
ATATGAATGTTATGAAACGTTTTATCATCCAAGCAATATGTTAATGTTTGTTGTAGGTGCAATTGATCCAGAGAAAACGA
TGGATTTGATACGTGAAAATCAAGCGAAAAAAGATTATAAAAACCAACCAGAAATAGTACGTTCATTCGAAGAAGAACCA
GATGAGGTAAATGAAAAGAAGAAAATTATTTCAATGCCTGTACAAACTCCGAAATGTTTAGTTGGTATTAAAGCGACAAA
CTTAAAAGAAAAAGGGGAAGCCCTTTTAAAACAAGAAATTGCGCTTACGTTACTTTTAGATTATTTATTTGGGAAAAGCT
CCGTTCATTACGAATCTTTATATAATGAAGGGCTCATTGATGATTCGTTCTCGTATGATTATACGGAAGAGAATAACTTC
GGTTTTGCAATGGTTGGCGGCGATACGAAGCAACCTGATGAGCTGGAAGAGCGTTTGAAAGGTATTTTATTAAATACAAA
TTATGATCAATTAGATGAGGCGGCATTAGAACGAGTAAAGAAAAAGAAAATAGGTGGCTTTTTACGTTCCTTGAATTCAC
CGGAATATATTGCAAATCAATTTACAAGATATGCGTTTAATGAATCGAGTCTGTTTGATGCATTGACTGTATTAGAAAGT
TTAACTGTTCAAGATTTACAAGAAGTAGCAAAATTATTATTATCAGAAGAAAAAATGAGCGTTTGTCAAGTGTTACCAAA
AAAATAA

Upstream 100 bases:

>100_bases
TACAGGTATTGAAAGTGTGACGAAAGAAGAGATTGTGAAAGTTGCTAAAAATATTGAATTAGATACAATTTACTTTTTAC
ACGGAACGGAGGGAGAATAA

Downstream 100 bases:

>100_bases
AAGGTTTCATAATAATACCCTCATCTTATCATTGATAAATTGTAAGATGAGGGTATTATTTATTTGTAGGGAAAAGATTT
TGTTGAGATAAGAGAGGAAT

Product: zinc protease, insulinase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MEKIVYEQLKETLYYEKLPNGLDVYILPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLMFVVGAIDPEKTMDLIRENQAKKDYKNQPEIVRSFEEEP
DEVNEKKKIISMPVQTPKCLVGIKATNLKEKGEALLKQEIALTLLLDYLFGKSSVHYESLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELEERLKGILLNTNYDQLDEAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLES
LTVQDLQEVAKLLLSEEKMSVCQVLPKK

Sequences:

>Translated_428_residues
MEKIVYEQLKETLYYEKLPNGLDVYILPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLMFVVGAIDPEKTMDLIRENQAKKDYKNQPEIVRSFEEEP
DEVNEKKKIISMPVQTPKCLVGIKATNLKEKGEALLKQEIALTLLLDYLFGKSSVHYESLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELEERLKGILLNTNYDQLDEAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLES
LTVQDLQEVAKLLLSEEKMSVCQVLPKK
>Mature_428_residues
MEKIVYEQLKETLYYEKLPNGLDVYILPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIRVPDGIAHFLEHKLFEKEDHD
AFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLNFVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLID
SLFVKHPIKIDIAGTIESISKITKDLLYECYETFYHPSNMLMFVVGAIDPEKTMDLIRENQAKKDYKNQPEIVRSFEEEP
DEVNEKKKIISMPVQTPKCLVGIKATNLKEKGEALLKQEIALTLLLDYLFGKSSVHYESLYNEGLIDDSFSYDYTEENNF
GFAMVGGDTKQPDELEERLKGILLNTNYDQLDEAALERVKKKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLES
LTVQDLQEVAKLLLSEEKMSVCQVLPKK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Escherichia coli, GI1787770, Length=240, Percent_Identity=26.6666666666667, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=427, Percent_Identity=23.6533957845433, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49214; Mature: 49214

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIVYEQLKETLYYEKLPNGLDVYILPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIR
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEE
VPDGIAHFLEHKLFEKEDHDAFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLIDSLFVKHPIKIDIAGTIESIS
HHHCCCCCHHHHHHHCCCCCCHHHEECCCCCCEEHHHHHHHHHHCCCEEEEECHHHHHHH
KITKDLLYECYETFYHPSNMLMFVVGAIDPEKTMDLIRENQAKKDYKNQPEIVRSFEEEP
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
DEVNEKKKIISMPVQTPKCLVGIKATNLKEKGEALLKQEIALTLLLDYLFGKSSVHYESL
HHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
YNEGLIDDSFSYDYTEENNFGFAMVGGDTKQPDELEERLKGILLNTNYDQLDEAALERVK
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHH
KKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLESLTVQDLQEVAKLLLSEEKMS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCQVLPKK
HHHHCCCC
>Mature Secondary Structure
MEKIVYEQLKETLYYEKLPNGLDVYILPKQGFNKTFATFTTKYGSVDNTFVPLGKEEMIR
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHEE
VPDGIAHFLEHKLFEKEDHDAFQLFSKQGASANAFTSFTRTAYLFSCTSNVEQNLNTLLN
CCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FVQEPYFSEKTVEKEKGIIGQEIQMYQDNPDWRLYFGLIDSLFVKHPIKIDIAGTIESIS
HHHCCCCCHHHHHHHCCCCCCHHHEECCCCCCEEHHHHHHHHHHCCCEEEEECHHHHHHH
KITKDLLYECYETFYHPSNMLMFVVGAIDPEKTMDLIRENQAKKDYKNQPEIVRSFEEEP
HHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
DEVNEKKKIISMPVQTPKCLVGIKATNLKEKGEALLKQEIALTLLLDYLFGKSSVHYESL
HHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
YNEGLIDDSFSYDYTEENNFGFAMVGGDTKQPDELEERLKGILLNTNYDQLDEAALERVK
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCEEECCCHHHHHHHHHHHHH
KKKIGGFLRSLNSPEYIANQFTRYAFNESSLFDALTVLESLTVQDLQEVAKLLLSEEKMS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VCQVLPKK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]