BacMap

Definition	Bacillus cereus Q1 chromosome, complete genome.
Accession	NC_011969
Length	5,214,195

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The map label for this gene is fabG [H]

Identifier: 222097232

GI number: 222097232

Start: 3527885

End: 3528598

Strand: Reverse

Name: fabG [H]

Synonym: BCQ_3572

Alternate gene names: 222097232

Gene position: 3528598-3527885 (Counterclockwise)

Preceding gene: 222097233

Following gene: 222097231

Centisome position: 67.67

GC content: 38.24

Gene sequence:

>714_bases
ATGAAAAAGTATGCATTAGTAACTGGAGGGAGCGGAGGGATTGGCTCTGCTATTTCGAAACAATTAATTCAAGATGGATA
TACAGTATATGTTCATTATAATAACAGTGAAGAGAAAGTGAATGAGTTGCAGAAAGAATGGGGTGAAGTAATTCCTGTTC
AAGCAAATTTAGCTTCTACTGATGGAGCAGAGCAATTGTGGAAACAAATTGAACATCCTCTTGATGTTATCGTATATGCA
GCTGGGAAGAGTATTTTTGGACTCGTAACAGATGTAACGAACGATGAATTGAATGATATGGTAGAACTTCAAGTGAAGAG
TATCTATAAATTATTATCGATGGCATTGCCATCTATGATTCAACGGAGAAGCGGTAATATTGTACTTGTTTCGTCTATAT
GGGGACAAATTGGCGCGTCATGTGAAGTTCTTTACTCGATGGTAAAAGGTGCGCAAAATTCATATGTGAAAGCTTTAGCA
AAAGAGGTTTCATTAAGTGGAATAAGAGTGAACGCGGTGGCGCCAGGTGCAATTGAAACGGAAATGTTAAACGTATTTTC
AGAAGAGGATAAGAATGAAATTGCGGAAGAGATTCCGTTAGGACGATTAGGATTACCGGAAGAAGTAGCAAAAACTGTGT
CATTTCTCGTATCACCAGGTGCATCTTATATAACTGGACAAATTATTGGAGTAAATGGCGGGTGGCATTGCTAA

Upstream 100 bases:

>100_bases
GTTTCATAATAATACCCTCATCTTATCATTGATAAATTGTAAGATGAGGGTATTATTTATTTGTAGGGAAAAGATTTTGT
TGAGATAAGAGAGGAATTGT

Downstream 100 bases:

>100_bases
AAATTTCTTACATAAAAAATGAAAAACTGTACAAATTAAGCATGATTCTATTACTAAGTAGTGAGGTGCTTACACATGTC
AGTTTTAGATAATTTTGATC

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC

Sequences:

>Translated_237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
>Mature_237_residues
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLASTDGAEQLWKQIEHPLDVIVYA
AGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMIQRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALA
KEVSLSGIRVNAVAPGAIETEMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=35.5371900826446, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=34.0248962655602, Blast_Score=110, Evalue=8e-25,
Organism=Homo sapiens, GI5031737, Length=240, Percent_Identity=35, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI15277342, Length=245, Percent_Identity=31.0204081632653, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=29.951690821256, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI19923817, Length=245, Percent_Identity=28.9795918367347, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=168, Percent_Identity=35.1190476190476, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI126723750, Length=244, Percent_Identity=27.8688524590164, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=33.6842105263158, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=24.6913580246914, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=26.1410788381743, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787335, Length=239, Percent_Identity=33.0543933054393, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=32.1138211382114, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=34.4262295081967, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367365, Length=234, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=30.6122448979592, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=29.7959183673469, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=27.3858921161826, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=24.1666666666667, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=29.3388429752066, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=27.4590163934426, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=28.9256198347107, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=25.2873563218391, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786701, Length=221, Percent_Identity=24.8868778280543, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=252, Percent_Identity=35.7142857142857, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=30.2040816326531, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.8, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=28.3333333333333, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=247, Percent_Identity=29.9595141700405, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=257, Percent_Identity=31.5175097276265, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=30.2325581395349, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=30.3149606299213, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17508651, Length=245, Percent_Identity=27.7551020408163, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=262, Percent_Identity=30.9160305343511, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=257, Percent_Identity=31.9066147859922, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.5343511450382, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=30.6818181818182, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=28.8461538461538, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=27.8225806451613, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=259, Percent_Identity=28.957528957529, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.5590551181102, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=209, Percent_Identity=24.8803827751196, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=26.7175572519084, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=27.6859504132231, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=242, Percent_Identity=23.9669421487603, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=28.6259541984733, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=254, Percent_Identity=29.1338582677165, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=27.027027027027, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=25.6505576208178, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=28.4615384615385, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=253, Percent_Identity=27.6679841897233, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=233, Percent_Identity=27.4678111587983, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320089, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24639444, Length=242, Percent_Identity=33.0578512396694, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=36.7768595041322, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=31.6, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=28.8065843621399, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=28.968253968254, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=28.5106382978723, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=178, Percent_Identity=34.2696629213483, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=26.5873015873016, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=29.3814432989691, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 25578; Mature: 25578

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLAST
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEECCCCCC
DGAEQLWKQIEHPLDVIVYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI
CCHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRVNAVAPGAIET
HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MKKYALVTGGSGGIGSAISKQLIQDGYTVYVHYNNSEEKVNELQKEWGEVIPVQANLAST
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCEEEEECCCCCC
DGAEQLWKQIEHPLDVIVYAAGKSIFGLVTDVTNDELNDMVELQVKSIYKLLSMALPSMI
CCHHHHHHHHCCCHHEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QRRSGNIVLVSSIWGQIGASCEVLYSMVKGAQNSYVKALAKEVSLSGIRVNAVAPGAIET
HHCCCCEEEEECHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCHHH
EMLNVFSEEDKNEIAEEIPLGRLGLPEEVAKTVSFLVSPGASYITGQIIGVNGGWHC
HHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]