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The map label for this gene is rihA [H]

Identifier: 222097005

GI number: 222097005

Start: 3290631

End: 3291509

Strand: Reverse

Name: rihA [H]

Synonym: BCQ_3345

Alternate gene names: 222097005

Gene position: 3291509-3290631 (Counterclockwise)

Preceding gene: 222097006

Following gene: 222097004

Centisome position: 63.13

GC content: 36.52

Gene sequence:

>879_bases
ATGTATGGATTGTTACATCCTGATATTGATATTGTTGGTGTAGTAACTGGATATGGAAATGTAACGCAAGAAAAGGCGAC
AAGTAATGCGGCATATTTATTGCAACTGGCAGGGCGGGAAGACATACCTGTTATTAATGGTGCGAAAATCCCTTTATCTG
GAGATATTACAACGTATTATCCAGAAATTCATGGGGCGGAAGGTTTAGGACCAATTCGACCGCCAAAAAATCTTTCTCCA
AATATAAAGCCTTTTTGTGAGTTTTTTGACATACTTGAAAAATATAAAGGAGAATTAATTATAGTTGATGCTGGTAGGTC
AACGACACTTGCGACAGCATTTATTTTAGAAAAACCATTGATGAAGTATGTGAAGGAATATTATATAATGGGCGGTGCTT
TTTTAATGCCTGGCAATGTGACACCAGTCGCAGAAGCGAATTTTCATGGTGATCCTATTGCATCACAATTAGTAATGCAA
AATGCCAAGAATGTGACATTGGTGCCGCTTAATGTTACATCTGAAGCTATAATTACGCCAGAGATGGTAAAGTACATTAC
GAAACATTCTAAAACGAGTTTTAATAAATTAATTGAACCGATTTTTACGTATTATTATAAAGCTTATAGAAAATTAAATC
CGAAAATAACAGGGAGTCCAGTACATGACGTCGTTACAATGATGGTTGCGGCAAATCCCTCTATTTTGGACTATGTATAC
CGCCGTGTCGATGTAGATACAGTAGGGATTGCAAAAGGAGAGAGTATTGCTGATTTTCGTCCTCAACCTGATGCAAAAGC
TTTAAAGAATTGGGTTCGAATTGGTTGGTCGTTACACTATAAAAAATTCCTCGAAGATTTCGTTAAAATTATGACGTAG

Upstream 100 bases:

>100_bases
GAATATTCATAAATTAATAACAATTGAGGGGATGGAGTTGAGGGTGATGAAAAAAGTATTGTTTTTAGGAGACCCGGGAA
TTGATGACTCTTTGGCAATT

Downstream 100 bases:

>100_bases
ACATAATGGGAGAATACAAGTTAAAATAATGGAGATGATTACTAAAATAATCATCTCCATTATTTTGTTTGTAAGAGATA
GATAGAGAAGAGCTACACAA

Product: inosine-uridine preferring nucleoside hydrolase

Products: D-ribose; purine

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MYGLLHPDIDIVGVVTGYGNVTQEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYYPEIHGAEGLGPIRPPKNLSP
NIKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPLMKYVKEYYIMGGAFLMPGNVTPVAEANFHGDPIASQLVMQ
NAKNVTLVPLNVTSEAIITPEMVKYITKHSKTSFNKLIEPIFTYYYKAYRKLNPKITGSPVHDVVTMMVAANPSILDYVY
RRVDVDTVGIAKGESIADFRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT

Sequences:

>Translated_292_residues
MYGLLHPDIDIVGVVTGYGNVTQEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYYPEIHGAEGLGPIRPPKNLSP
NIKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPLMKYVKEYYIMGGAFLMPGNVTPVAEANFHGDPIASQLVMQ
NAKNVTLVPLNVTSEAIITPEMVKYITKHSKTSFNKLIEPIFTYYYKAYRKLNPKITGSPVHDVVTMMVAANPSILDYVY
RRVDVDTVGIAKGESIADFRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT
>Mature_292_residues
MYGLLHPDIDIVGVVTGYGNVTQEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYYPEIHGAEGLGPIRPPKNLSP
NIKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPLMKYVKEYYIMGGAFLMPGNVTPVAEANFHGDPIASQLVMQ
NAKNVTLVPLNVTSEAIITPEMVKYITKHSKTSFNKLIEPIFTYYYKAYRKLNPKITGSPVHDVVTMMVAANPSILDYVY
RRVDVDTVGIAKGESIADFRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786871, Length=265, Percent_Identity=28.3018867924528, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788486, Length=262, Percent_Identity=26.3358778625954, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786213, Length=281, Percent_Identity=27.0462633451957, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI32565474, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320608, Length=268, Percent_Identity=30.2238805970149, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022975 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: 3.2.2.1

Molecular weight: Translated: 32508; Mature: 32508

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGLLHPDIDIVGVVTGYGNVTQEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYY
CCCCCCCCCEEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEC
PEIHGAEGLGPIRPPKNLSPNIKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
MKYVKEYYIMGGAFLMPGNVTPVAEANFHGDPIASQLVMQNAKNVTLVPLNVTSEAIITP
HHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEECH
EMVKYITKHSKTSFNKLIEPIFTYYYKAYRKLNPKITGSPVHDVVTMMVAANPSILDYVY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
RRVDVDTVGIAKGESIADFRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT
HHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYGLLHPDIDIVGVVTGYGNVTQEKATSNAAYLLQLAGREDIPVINGAKIPLSGDITTYY
CCCCCCCCCEEEEEEECCCCCHHHHHCCCCEEEEEECCCCCCCEECCCCCCCCCCCEEEC
PEIHGAEGLGPIRPPKNLSPNIKPFCEFFDILEKYKGELIIVDAGRSTTLATAFILEKPL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHH
MKYVKEYYIMGGAFLMPGNVTPVAEANFHGDPIASQLVMQNAKNVTLVPLNVTSEAIITP
HHHHHHHHHHCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCEECH
EMVKYITKHSKTSFNKLIEPIFTYYYKAYRKLNPKITGSPVHDVVTMMVAANPSILDYVY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
RRVDVDTVGIAKGESIADFRPQPDAKALKNWVRIGWSLHYKKFLEDFVKIMT
HHCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-D-ribosylpurine; H2O

Specific reaction: an N-D-ribosylpurine + H2O = D-ribose + a purine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA