Click here to switch to the map view.

The map label for this gene is yplQ [C]

Identifier: 222095839

GI number: 222095839

Start: 2155703

End: 2156359

Strand: Reverse

Name: yplQ [C]

Synonym: BCQ_2179

Alternate gene names: 222095839

Gene position: 2156359-2155703 (Counterclockwise)

Preceding gene: 222095845

Following gene: 222095832

Centisome position: 41.36

GC content: 35.92

Gene sequence:

>657_bases
ATGACTGAAAAAATGACACGAATGACCCAATTTGTAAAAGAAGAAATTGCAAATGCAATAACACATGGTATCGGTGCCAT
TTTAAGCATCCCTGCCTTAATCATATTGATTATTCATGCTTCTAAGCATGGTACCGCATCAGCTGTAGTTGCATTTACTG
TTTATGGTGTAAGTATGTTCTTACTGTACTTATTTTCAACGTTGCTACATAGCATTCATCATCCTAAAGTAAAAAAAATA
TTTACTATTTTAGATCATTCAGCCATTTACTTATTGATTGCTGGCACGTATACTCCTTTTCTACTTATTACACTCCGCGG
CCCATTAGGATGGACATTACTTGCTATTATATGGATCCTTGCAATCGGAGGTATCATCTTCAAAATTTTCTTTGTACGTC
GCTTTATTAAGGCATCAACGCTATGTTATATCATAATGGGATGGCTCATAATCGTTGCTATTAAACCACTTTATGAAAAT
CTAACTGGACATGGTTTTTCACTACTTTTAGCAGGTGGTATTTTATATTCTGTAGGAGCTATATTCTTCCTTTGGGAAAA
GTTACCGTTCAATCATGCCATTTGGCATCTTTTCGTATTAGGTGGTAGCGCGATGATGTTCTTCTGCGTACTCTTTTACG
TCTTACCTACGGCATAA

Upstream 100 bases:

>100_bases
CTGCCCGTAAAAGCCCGATTGATTCAACTAATAATCAGTGGGGGGGATGCCCCTCCACTGATTAAAGTTTCACTTTATAA
TAGTAGAAAGGATTACCATT

Downstream 100 bases:

>100_bases
TAAAAAAGGTTTCAGCTTTATGTAAGCTGAAACCTTTTTTATTACTTATGTAATTGTGATGCGATAACATCCTGTGTATG
CTTCGTTAACTCTTTAATAT

Product: hemolysin iii

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVKKI
FTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWILAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Sequences:

>Translated_218_residues
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVKKI
FTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWILAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYEN
LTGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
>Mature_217_residues
TEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMFLLYLFSTLLHSIHHPKVKKIF
TILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWILAIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENL
TGHGFSLLLAGGILYSVGAIFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=223, Percent_Identity=30.4932735426009, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI52630445, Length=215, Percent_Identity=29.3023255813954, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI154759277, Length=246, Percent_Identity=28.0487804878049, Blast_Score=78, Evalue=8e-15,
Organism=Escherichia coli, GI1789266, Length=216, Percent_Identity=43.9814814814815, Blast_Score=180, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI71996356, Length=213, Percent_Identity=31.924882629108, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640324, Length=228, Percent_Identity=28.9473684210526, Blast_Score=77, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 24331; Mature: 24200

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLYLFSTLLHSIHHPKVKKIFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWIL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
AIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEKMTRMTQFVKEEIANAITHGIGAILSIPALIILIIHASKHGTASAVVAFTVYGVSMF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LLYLFSTLLHSIHHPKVKKIFTILDHSAIYLLIAGTYTPFLLITLRGPLGWTLLAIIWIL
HHHHHHHHHHHHCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
AIGGIIFKIFFVRRFIKASTLCYIIMGWLIIVAIKPLYENLTGHGFSLLLAGGILYSVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IFFLWEKLPFNHAIWHLFVLGGSAMMFFCVLFYVLPTA
HHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]