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The map label for this gene is isp [H]

Identifier: 222095642

GI number: 222095642

Start: 1960039

End: 1960989

Strand: Direct

Name: isp [H]

Synonym: BCQ_1982

Alternate gene names: 222095642

Gene position: 1960039-1960989 (Clockwise)

Preceding gene: 222095641

Following gene: 222095646

Centisome position: 37.59

GC content: 38.07

Gene sequence:

>951_bases
ATGAATAGTAGTACAGCGAATAAACAAAAAGGTATACAATTGATTCCTTTTACAGTAGATAAGGTGGTTGAACAAGTAAA
TGAAATTCCGCCAGGTGTACAACTCATTCATGCTCCACAAGTATGGGAGAAGAGTGCAAAAGGAAAAGATATTGTTGTTG
CCGTATTAGATACAGGGTGTGATATGAATCATATAGATTTAAAGGATCGTATTATCGGTGGAAGAAATTTCACGAAAGAT
TACGAAGGAGATCCAAATATATATCTTGATAATAACGGACACGGTACTCATGTAGCTGGGACAATTGCAGCGACTGAAAA
TGGTGTCGGTGTTTTAGGAGTCGCACCACTTGCTAAAATGTTAGTGTTAAAGGTTTTAGCAGGAGATGGTTCTGGAAGTT
ATGAGCAAATTATTGAGGCGATACATTATGCTGTAAATTGGAGAGGGCCTAATAAAGAAAGAGTTAGAGTCATTTCCATG
TCACTTGGTGGCCCACAAGATGTTCCAGAATTACATGAAGCAATTCAAAATGCAGTAAAGCAGGATGTTCTCGTCGTATG
TGCTGCTGGAAATAATGGAGATTGTAATGATAATACGGAGGAACTAGATTTCCCAGGTGCATACTCAGAAGTAATTGAAG
TGGGTGCCGTCAATTTAGAGCGGAAAATCGCATGTTTTAGTAATTCAAATCAAGAAATTGATTTAGTGGCGCCAGGCGAT
GAAATATTATCTACGTATCCTGAAGGGAAATATGCGGTATTAAGTGGAACTTCTATGGCCACACCGCATGTCGCTGGAGC
ACTGGCATTGCTCATAAAGCAGTGTGAAAGGGAATATGGTAGAAAGTTATCAGAACCAGAAATATATGCACAACTTATTA
AAAGAACTGTACCTTTAGGATATGAACGTACATCTGAAGGGAATGGTTTATTAGATTTATTAAAAGAATAG

Upstream 100 bases:

>100_bases
TTTTAAGGAAGGAAAACGAAACACATAAAACGAATGTTAAATGTAAGTGTTTTCAAAAGTGGTCTGAAATGAAAATAATA
TATTTTCAGGAGGGATTACA

Downstream 100 bases:

>100_bases
AAAATACTAAAAAACATTTCATATTCATATGAGATGTTTTTTAGTATGGTTCTGTCGCATATATAGTGGAATCTAGTCTT
GAATTCTTTTTCAAGAAATG

Product: intracellular serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLLDLLKE

Sequences:

>Translated_316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLLDLLKE
>Mature_316_residues
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGCDMNHIDLKDRIIGGRNFTKD
YEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKMLVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISM
SLGGPQDVPELHEAIQNAVKQDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLGYERTSEGNGLLDLLKE

Specific function: Involved in the generation of beta- and alpha-amylases from the large amylase precursor [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=299, Percent_Identity=29.0969899665552, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=233, Percent_Identity=36.9098712446352, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6324576, Length=235, Percent_Identity=35.3191489361702, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319893, Length=261, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550681, Length=252, Percent_Identity=29.7619047619048, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500 [H]

Pfam domain/function: PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 34057; Mature: 34057

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGC
CCCCCCCHHCCCEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCEEEEEEEECCC
DMNHIDLKDRIIGGRNFTKDYEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKM
CCCCCCHHHHEECCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCEEEEHHHHHHH
LVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISMSLGGPQDVPELHEAIQNAVK
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
QDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHEEEEECCCCCEEEEECCCH
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLG
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YERTSEGNGLLDLLKE
CCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNSSTANKQKGIQLIPFTVDKVVEQVNEIPPGVQLIHAPQVWEKSAKGKDIVVAVLDTGC
CCCCCCCHHCCCEEECCCHHHHHHHHHHCCCCCEEEECCHHHHHCCCCCEEEEEEEECCC
DMNHIDLKDRIIGGRNFTKDYEGDPNIYLDNNGHGTHVAGTIAATENGVGVLGVAPLAKM
CCCCCCHHHHEECCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCEEEEHHHHHHH
LVLKVLAGDGSGSYEQIIEAIHYAVNWRGPNKERVRVISMSLGGPQDVPELHEAIQNAVK
HHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
QDVLVVCAAGNNGDCNDNTEELDFPGAYSEVIEVGAVNLERKIACFSNSNQEIDLVAPGD
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHEEEEECCCCCEEEEECCCH
EILSTYPEGKYAVLSGTSMATPHVAGALALLIKQCEREYGRKLSEPEIYAQLIKRTVPLG
HHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
YERTSEGNGLLDLLKE
CCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1834632 [H]