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The map label for this gene is yisV [H]

Identifier: 222095631

GI number: 222095631

Start: 1950344

End: 1951786

Strand: Direct

Name: yisV [H]

Synonym: BCQ_1971

Alternate gene names: 222095631

Gene position: 1950344-1951786 (Clockwise)

Preceding gene: 222095629

Following gene: 222095632

Centisome position: 37.4

GC content: 33.82

Gene sequence:

>1443_bases
ATGGAAAGATTCGTTTGGAAACCGAATATGTCTCTAGCGACTCCTCTATATAAACAAATAGAAACGTATATTAAGGAAAG
AATCGTTAATGGTGAATGGACTGTTGGAACGAAATTACCTTCGCAAAGAGATTTGGCACATATATTTGGTGTGAACCGGA
GTACAATTGTAATGGCTTTCGATGAACTAGCCGCAAAGGGGTATATTGAAGGGAATGGCAGAAAAGGAACAATTGTTGTA
AATAATAATGAGAATGCTTCAATATACGCACCCCCGCCTAATTGGCAGTCTTATGTAGAAAAAGGACTTCATTATCCAAA
TCTGCCTGCTATTCAAGAAATTAATCAAGCTGAATTTTATCCGCATGTAATTCGTTTAGGAACAGGTGAACTCGCGCCAA
GTCTTTTACCTGAAAAAAAGATGAAAGATATTATGAATAAGCTTTTAAAGTCGAACATGATACTTGGATATGAAGAACCG
AAAGGGAATTTTTATTTAAGGAAGAAAATTGCGGACTATTTAAAAGGACATGGTGTATATGTAACTCCTGATTCTATATT
AATTGTTTCAGGGGCAATTCAAGCGTTGCAACTTATTTCTATGGGGCTTCTACCAAAAGGGGCATCTATCTTATTAGAAA
AACCATCTTATTTATATTCTCTTAATGTTTTTCAATCAGCAGGAATGCGATTAATTGGTATGCCGATGGATGAAAACGGT
TTACATGCATCATATATTCCAAAATATAAGAAGCAATTTAATGCATCTATTTTATATACAATCCCGTCTTTTCATAATCC
GACGAACTTTAGTATGAATGCGAAGAAACGGATAGAAGTAATGGAAATATGTAATGAAATTGGATTGCCTATTATAGAGG
ACGCGGTATATCAAGACTTATGGTTTGATAAGCCTATTTCAAAGCCTTTAAAGGCATATGATAAAAACGGAATTGTACTA
CATATTGGGAGTATGTCTAAAGTCATTAGTCCAGGATTAAGAATCGGATGGATTGTTGGATCAGAGCCAGTCATTCAAAG
ATTGGCGGATATAAAAATGCAAACGGATTATGGCTCGAGTTCAATCTCCCAGCAAATTGCAGCGGAATGGTTTACAAATG
GATTGTATGATGAACATTTACTGTTTGTAAGAACTCAGTTGAAAAAACGTAGAGATTTTATGTTAAAAATGTTAGAGGAA
TATTTTTGTGATATAGCAACTTGGTATGAACCAGTAGGTGGTTTTTATATTTGGTTACATATGAATGTACCCGTTTCAAA
CCGTAGCTTATTTGACAAAGCTTTGAAAGAAAAGATTTTATTAAATCTAGGTACTTTGTATGATAGAAGTGCAAATCAAT
TTTTGCGCTTATCATATTCATATGCAACATTAGAAGAAATTGAAATAGGTATAAAAAAACTTGCACAACTAATGAAAAAG
TAA

Upstream 100 bases:

>100_bases
AATTTATTATGATAGTGTATATTGTATAGAAGAAATGAAAATTTGTATCCATCCATATGGTTGGGGAGGTTACCAACCAA
AAAGAATATAAGGTGATATG

Downstream 100 bases:

>100_bases
GAGGAGAAAGTAATGAAACAATATGTAATTTGCCAAATTATCAATGGAGAAAAATATTTAGCTGCTTATGCGGAGACGAA
GCAGGAAGCAATTGAAAAAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MERFVWKPNMSLATPLYKQIETYIKERIVNGEWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIVV
NNNENASIYAPPPNWQSYVEKGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEP
KGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGMPMDENG
LHASYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIVL
HIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFTNGLYDEHLLFVRTQLKKRRDFMLKMLEE
YFCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNLGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAQLMKK

Sequences:

>Translated_480_residues
MERFVWKPNMSLATPLYKQIETYIKERIVNGEWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIVV
NNNENASIYAPPPNWQSYVEKGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEP
KGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGMPMDENG
LHASYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIVL
HIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFTNGLYDEHLLFVRTQLKKRRDFMLKMLEE
YFCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNLGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAQLMKK
>Mature_480_residues
MERFVWKPNMSLATPLYKQIETYIKERIVNGEWTVGTKLPSQRDLAHIFGVNRSTIVMAFDELAAKGYIEGNGRKGTIVV
NNNENASIYAPPPNWQSYVEKGLHYPNLPAIQEINQAEFYPHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEP
KGNFYLRKKIADYLKGHGVYVTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGMPMDENG
LHASYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDLWFDKPISKPLKAYDKNGIVL
HIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSSSISQQIAAEWFTNGLYDEHLLFVRTQLKKRRDFMLKMLEE
YFCDIATWYEPVGGFYIWLHMNVPVSNRSLFDKALKEKILLNLGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAQLMKK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=27.7070063694268, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=27.7070063694268, Blast_Score=123, Evalue=4e-28,
Organism=Escherichia coli, GI1787710, Length=485, Percent_Identity=25.1546391752577, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1790797, Length=473, Percent_Identity=26.0042283298097, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788722, Length=319, Percent_Identity=24.1379310344828, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=359, Percent_Identity=21.4484679665738, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321929, Length=351, Percent_Identity=21.0826210826211, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356535, Length=397, Percent_Identity=21.1586901763224, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54686; Mature: 54686

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFVWKPNMSLATPLYKQIETYIKERIVNGEWTVGTKLPSQRDLAHIFGVNRSTIVMAF
CCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCHHHHHCCCCCEEEEEE
DELAAKGYIEGNGRKGTIVVNNNENASIYAPPPNWQSYVEKGLHYPNLPAIQEINQAEFY
HHHHHCCEEECCCCEEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHCCHHHCC
PHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEPKGNFYLRKKIADYLKGHGVY
CHHEEECCCHHCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCCCEE
VTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGMPMDENG
ECCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEHHHHHCCCEEEECCCCCCC
LHASYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDL
CCHHHCCHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
WFDKPISKPLKAYDKNGIVLHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSS
HCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHCEEECCCCCH
SISQQIAAEWFTNGLYDEHLLFVRTQLKKRRDFMLKMLEEYFCDIATWYEPVGGFYIWLH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
MNVPVSNRSLFDKALKEKILLNLGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAQLMKK
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERFVWKPNMSLATPLYKQIETYIKERIVNGEWTVGTKLPSQRDLAHIFGVNRSTIVMAF
CCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHCHHHHHCCCCCEEEEEE
DELAAKGYIEGNGRKGTIVVNNNENASIYAPPPNWQSYVEKGLHYPNLPAIQEINQAEFY
HHHHHCCEEECCCCEEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCHHHHHCCHHHCC
PHVIRLGTGELAPSLLPEKKMKDIMNKLLKSNMILGYEEPKGNFYLRKKIADYLKGHGVY
CHHEEECCCHHCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHHHCCCCEE
VTPDSILIVSGAIQALQLISMGLLPKGASILLEKPSYLYSLNVFQSAGMRLIGMPMDENG
ECCCCEEEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEHHHHHCCCEEEECCCCCCC
LHASYIPKYKKQFNASILYTIPSFHNPTNFSMNAKKRIEVMEICNEIGLPIIEDAVYQDL
CCHHHCCHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
WFDKPISKPLKAYDKNGIVLHIGSMSKVISPGLRIGWIVGSEPVIQRLADIKMQTDYGSS
HCCCCCCCHHHHHCCCCEEEEECCHHHHHCCCCEEEEEECCHHHHHHHHHCEEECCCCCH
SISQQIAAEWFTNGLYDEHLLFVRTQLKKRRDFMLKMLEEYFCDIATWYEPVGGFYIWLH
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
MNVPVSNRSLFDKALKEKILLNLGTLYDRSANQFLRLSYSYATLEEIEIGIKKLAQLMKK
EECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]