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The map label for this gene is mgtB [H]

Identifier: 222095306

GI number: 222095306

Start: 1613532

End: 1614257

Strand: Direct

Name: mgtB [H]

Synonym: BCQ_1646

Alternate gene names: 222095306

Gene position: 1613532-1614257 (Clockwise)

Preceding gene: 222095305

Following gene: 222095307

Centisome position: 30.94

GC content: 33.61

Gene sequence:

>726_bases
ATGTTATATGCAAACAAAACTGTGGGTAACACGTCATATAAATTAAGCAAAAAATCAATGAAAGAACAAACGATGCTTCA
AAAAAATAAAGATTTATTAATTGAAATCGCAACGAGAGATGTAAAATCTGTATTTGCGTATTTTAAAACAACAAGAGATG
GATTGTCTATGAAAGAGGCACAAAAACGTATTCAAGTATACGGCCGAAATGAATTAACTTCAAAAAGAGCTCGTATTGCA
GAAGTGATGATGAAGCTAGGTGGAATGATCCCAGGTTTTTCAAAACAACATGTGAGAGATGGATTACAATGTGAGAAGAT
TACTGTGTCTCGAGTAGAATGTTCTAGTGTAACAGGTTTAAACGGTGAATTAAAAATGATGGATTTGCCAGTACAAGAGC
TTGTTCCAGGAGATATGATTTTCCTTTCAGAAGGTGATACAGTACCAGCAGATGTACGTATCATTTATGCAAATGATCTA
TTAGTAAATGAATCTGTGCTAACAGGAAACGATGCAAGTGTTGAGAAATTTGAAAGTTGCTATCATCTTGAACGCAAACG
ATTTATTCCTTTGAAAAGAATGAAAGACTATAATCCACTTGAACTTGAAAATGTATGTTTCAAAGGGACGTATATTGTTA
GTGGAAATGCAAAAGCTGTAGTAGTTTCAACTGGGAAAAATACGTATACAGGGATTCTTCATACTTGTTGTAGTAAAACG
TCTTAA

Upstream 100 bases:

>100_bases
CGTTTATATGTATGTTTAGGCGCTAGACACTTTCACCGTAAAGTGGATAAATTGAGAAACAAAGCGTTTCTTCCTACGTT
GTAAAGGAGGAGACGATAAT

Downstream 100 bases:

>100_bases
TGTGTAAATGATGCTAAATATACAAAAACAATGTATAATAGACAAAGTTGAAAAACGTAGAATGGTAATCTATTTATATA
ACCTTACGTGATGACGTGGG

Product: cation transporter

Products: NA

Alternate protein names: Mg(2+) transport ATPase, P-type 1 [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLYANKTVGNTSYKLSKKSMKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRARIA
EVMMKLGGMIPGFSKQHVRDGLQCEKITVSRVECSSVTGLNGELKMMDLPVQELVPGDMIFLSEGDTVPADVRIIYANDL
LVNESVLTGNDASVEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGTYIVSGNAKAVVVSTGKNTYTGILHTCCSKT
S

Sequences:

>Translated_241_residues
MLYANKTVGNTSYKLSKKSMKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRARIA
EVMMKLGGMIPGFSKQHVRDGLQCEKITVSRVECSSVTGLNGELKMMDLPVQELVPGDMIFLSEGDTVPADVRIIYANDL
LVNESVLTGNDASVEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGTYIVSGNAKAVVVSTGKNTYTGILHTCCSKT
S
>Mature_241_residues
MLYANKTVGNTSYKLSKKSMKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRARIA
EVMMKLGGMIPGFSKQHVRDGLQCEKITVSRVECSSVTGLNGELKMMDLPVQELVPGDMIFLSEGDTVPADVRIIYANDL
LVNESVLTGNDASVEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGTYIVSGNAKAVVVSTGKNTYTGILHTCCSKT
S

Specific function: Mediates magnesium influx to the cytosol [H]

COG id: COG0474

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily [H]

Homologues:

Organism=Homo sapiens, GI153946397, Length=115, Percent_Identity=35.6521739130435, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI118498343, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI22748667, Length=112, Percent_Identity=36.6071428571429, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI21361181, Length=121, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI237681109, Length=121, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=9e-11,
Organism=Homo sapiens, GI237681111, Length=121, Percent_Identity=36.3636363636364, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI2367363, Length=112, Percent_Identity=42.8571428571429, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321271, Length=103, Percent_Identity=35.9223300970874, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762455, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762453, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762447, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762457, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762449, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762445, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24762451, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17136664, Length=111, Percent_Identity=36.9369369369369, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161085803, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24668704, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24668708, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24668696, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281366617, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006068
- InterPro:   IPR004014
- InterPro:   IPR001757
- InterPro:   IPR006415
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00689 Cation_ATPase_C; PF00690 Cation_ATPase_N; PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.2 [H]

Molecular weight: Translated: 27032; Mature: 27032

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYANKTVGNTSYKLSKKSMKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEA
CCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
QKRIQVYGRNELTSKRARIAEVMMKLGGMIPGFSKQHVRDGLQCEKITVSRVECSSVTGL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEEEEEECCCCCC
NGELKMMDLPVQELVPGDMIFLSEGDTVPADVRIIYANDLLVNESVLTGNDASVEKFESC
CCCEEEEECCHHHHCCCCEEEEECCCCCCCCEEEEEECCEEEECCEECCCCCCHHHHHHH
YHLERKRFIPLKRMKDYNPLELENVCFKGTYIVSGNAKAVVVSTGKNTYTGILHTCCSKT
HHHHHHHCCCHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MLYANKTVGNTSYKLSKKSMKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEA
CCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
QKRIQVYGRNELTSKRARIAEVMMKLGGMIPGFSKQHVRDGLQCEKITVSRVECSSVTGL
HHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEEEEEECCCCCC
NGELKMMDLPVQELVPGDMIFLSEGDTVPADVRIIYANDLLVNESVLTGNDASVEKFESC
CCCEEEEECCHHHHCCCCEEEEECCCCCCCCEEEEEECCEEEECCEECCCCCCHHHHHHH
YHLERKRFIPLKRMKDYNPLELENVCFKGTYIVSGNAKAVVVSTGKNTYTGILHTCCSKT
HHHHHHHCCCHHHCCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1824701; 11677609; 7751273 [H]