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The map label for this gene is aroB

Identifier: 222095246

GI number: 222095246

Start: 1556948

End: 1558045

Strand: Direct

Name: aroB

Synonym: BCQ_1586

Alternate gene names: 222095246

Gene position: 1556948-1558045 (Clockwise)

Preceding gene: 222095245

Following gene: 222095247

Centisome position: 29.86

GC content: 37.61

Gene sequence:

>1098_bases
ATGGAAAACATACATATTCAAACGAAATCAAAAGAATATGATGTACATGTAGGAAAAGAATCGTTGTCACATTTGACAAC
AATCGTTCAAAACATGCAGCCATCTGTATCAAATATTATGATTATTTCAGATGAGGCTGTTGCACCTTTACATTTACAGA
CAGTTGTAGATGCGTTGCAAATAGATCAAAAAGTATTTTCATTCGTTGTACCGAGTGGTGAAAAAGAGAAGTCCTTTGAA
AATTTCTATGCGGCTCATACGTCAGCTCTTGAAAATAAATTAGATAGAAATTCTTTAATTATCGCACTTGGAGGCGGGAT
GATTGGAGATTTAGCTGGTTTTGTTGCTGCGTCGTTTATGCGTGGAATTCGCTTTGTTCAAGTTCCGACTACTTTATTAG
CTCACGATAGCGCGGTAGGTGGGAAAGTAGCAATCAATCATCCGTTAGGTAAAAATATGATAGGTGCATTCCATCAACCA
GAAGCAGTTGTATATCATACGCCGTTTTTACAGTCTCTTCCTGAAAAAGAGTGGCGCTCAGGTTATGCAGAAGTGATAAA
ACATGCTCTAATTGGTGATGTAAAGCTATATCATTGGCTAAAAGAAGAAGTGCAAACATTAGCAGATCTTCGTGATGAGA
AATTAATCCACATATTAACGAAGGCGATTCCTGTAAAGGCAAACATTGTAGCGCAAGATGAAACAGAAAAAGGCGTACGT
GCACATTTAAACTTTGGACATACGTTAGGCCATGCTCTAGAAAAAGAACTAGGATATGGAAATATTACTCACGGTGACGG
AGTAGCGGTTGGAATGTTATTTGCTATATTCTTAAGTGAACAAGTGTATAAGGTAAATCTTGCTTATGAAGAGATGAAGC
AGTGGTTCTTGAAGTACGGCTATCCAAAAATGCCAAGTGATTTAAGTGTAGAACGCCTCGTTGGGTTGATGAAACAAGAT
AAGAAAGCGAATGCAGGAACAATTCATATGGTACTTATGCAGGAATATGGGGTAGTGAATGTCGTATCTATTCCTGATGA
GACTGTTCATATTGCGTTAGAGGCATTTCAAAAGGATATGGGTATAAGAAGTAGATAA

Upstream 100 bases:

>100_bases
GGGAATTAGCGACAGCTTTAATAGAACAATTTGGATTAGATCGTATGGACCTTATTCGTGAAAATATTGAGAAACATAAT
GAATATGCGAGGGGATTTTA

Downstream 100 bases:

>100_bases
CAGCTATGGAGAGCCTATTTAGAAGCATTTTCGTAATAGTGACAGTTATGATAAACAATTATAGTAAGGGAGTATAACCG
TATTGTAATCGAATTGAATA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MENIHIQTKSKEYDVHVGKESLSHLTTIVQNMQPSVSNIMIISDEAVAPLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMGIRSR

Sequences:

>Translated_365_residues
MENIHIQTKSKEYDVHVGKESLSHLTTIVQNMQPSVSNIMIISDEAVAPLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMGIRSR
>Mature_365_residues
MENIHIQTKSKEYDVHVGKESLSHLTTIVQNMQPSVSNIMIISDEAVAPLHLQTVVDALQIDQKVFSFVVPSGEKEKSFE
NFYAAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQP
EAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYGYPKMPSDLSVERLVGLMKQD
KKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDMGIRSR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=336, Percent_Identity=40.4761904761905, Blast_Score=237, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6320332, Length=372, Percent_Identity=32.7956989247312, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_BACC7 (B7HL27)

Other databases:

- EMBL:   CP001177
- RefSeq:   YP_002337642.1
- EnsemblBacteria:   EBBACT00000092269
- GeneID:   7077323
- GenomeReviews:   CP001177_GR
- KEGG:   bcr:BCAH187_A1680
- GeneTree:   EBGT00050000002325
- HOGENOM:   HBG632303
- OMA:   EHAIATS
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 40546; Mature: 40546

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIHIQTKSKEYDVHVGKESLSHLTTIVQNMQPSVSNIMIISDEAVAPLHLQTVVDALQ
CCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHC
GIRSR
CCCCC
>Mature Secondary Structure
MENIHIQTKSKEYDVHVGKESLSHLTTIVQNMQPSVSNIMIISDEAVAPLHLQTVVDALQ
CCCEEEEECCCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHH
IDQKVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLIIALGGGMIGDLAGFVAASFM
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRS
HCCEEEEECHHHHHCCCCCCCEEEECCCCCCHHHCCCCCCCEEEEECHHHHHCCHHHHHC
GYAEVIKHALIGDVKLYHWLKEEVQTLADLRDEKLIHILTKAIPVKANIVAQDETEKGVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCE
AHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVNLAYEEMKQWFLKYG
ECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCHHEEEECHHHHHHHHHHHCC
YPKMPSDLSVERLVGLMKQDKKANAGTIHMVLMQEYGVVNVVSIPDETVHIALEAFQKDM
CCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHCCEEEEEECCCHHHHHHHHHHHHHC
GIRSR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA