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The map label for this gene is citT [H]

Identifier: 222094311

GI number: 222094311

Start: 614693

End: 615385

Strand: Direct

Name: citT [H]

Synonym: BCQ_0625

Alternate gene names: 222094311

Gene position: 614693-615385 (Clockwise)

Preceding gene: 222094310

Following gene: 222094313

Centisome position: 11.79

GC content: 36.65

Gene sequence:

>693_bases
ATGGGTGAGGAGATTGAAGTATTGATTGTAGAAGATGATATTCGAATTGCAGACATTCATCGTCGTTTTACTGAAAAGAT
TGAGGGATTTAAAGTAATTGGAACAGCGACGACTGGGGAACAAGCGAAAGAATGGCTAGATCTTGTGAAACCACAGCTCG
TTTTATTAGACGTGTACTTACCTGATATGCAAGGAACGGAACTTGTCACATATATTAGACATAATTTACATGATACAGAT
ATTATTATGATTACAGCTGCATCGGAAACAGATGTAGTGAGGCACGCCCTGCGAGGTGGAGTAACAGATTATATCGTAAA
GCCACTTATGTTTGATCGATTTAAAACAAGTTTGGAAAATTACCAAAAAAAGCTTGTGCAGTTAAAGAAAAATAACCAAT
TATCTATCGAACAAATAGAACATTTATGGTCTCAAAGAGGCGTAAAGGGAAATGAAATAGAATATGCCCCGAAAGGTATA
GACCCCTTAACTTTAGCAAAAATAAAAAAGCATATGTTAACAGTGAATGAAGAAGGTATTACTGCGGAAGTGCTAAGCTC
AATGGTCGGAGTAAGCAGATCGACAGCGAGGCGTTATTTAGAATATTTAATATCAGGAAAGAAAGTTCATGCGGAGCTTA
TATATGGGAGTGTTGGGAGACCAGAAAGAAGATATTTTCTTATTCCTTCATAA

Upstream 100 bases:

>100_bases
AGTTAGTAGAAGATTTAAATGGAAGTATCGCAATCGAAAAAGGGGATTTAGGTGGTGCATTGTTTATTATTGCATTACCA
AAAGAGAGAGGCGAATTGTA

Downstream 100 bases:

>100_bases
TAAAAAACAGTAGAGGATATATGTCCGCTACTGTTTTTTTATTTTATATTGGAATAACCCCAATTAAAATTCCAGTAATC
AACATTACCATTGTCGTTCC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHNLHDTD
IIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKTSLENYQKKLVQLKKNNQLSIEQIEHLWSQRGVKGNEIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLIPS

Sequences:

>Translated_230_residues
MGEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHNLHDTD
IIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKTSLENYQKKLVQLKKNNQLSIEQIEHLWSQRGVKGNEIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLIPS
>Mature_229_residues
GEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHNLHDTDI
IMITAASETDVVRHALRGGVTDYIVKPLMFDRFKTSLENYQKKLVQLKKNNQLSIEQIEHLWSQRGVKGNEIEYAPKGID
PLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLIPS

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=229, Percent_Identity=36.6812227074236, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790566, Length=228, Percent_Identity=31.5789473684211, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788222, Length=103, Percent_Identity=33.0097087378641, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26278; Mature: 26147

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHNLHDTDIIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKTSLEN
CCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YQKKLVQLKKNNQLSIEQIEHLWSQRGVKGNEIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLIPS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCC
>Mature Secondary Structure 
GEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYL
CCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHNLHDTDIIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKTSLEN
CCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YQKKLVQLKKNNQLSIEQIEHLWSQRGVKGNEIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLIPS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]