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The map label for this gene is gntK [H]

Identifier: 222093930

GI number: 222093930

Start: 161805

End: 163340

Strand: Direct

Name: gntK [H]

Synonym: BCQ_0186

Alternate gene names: 222093930

Gene position: 161805-163340 (Clockwise)

Preceding gene: 222093929

Following gene: 222093931

Centisome position: 3.1

GC content: 38.87

Gene sequence:

>1536_bases
ATGAGTAGCTATATGTTAGGTATAGATATCGGTACAACAAGTACGAAAGCAGTTTTATTTACTGAAAAAGGCGAAGTCAT
TCAAACCGAGAATATTGGTTATCCACTTCGCACACCGGATATATCCACAGCGGAACAAGATCCAGAAGAGATTTTCCAAG
CTGTTTTACAAGCGATATCAAATATAACGAAACAGCATTCAGATAAAAAACCATCGTTTATTTCATTTAGCAGTGCTATG
CATAGTGTCATTGCCATGGATGAAAATGATCAGCCGCTGACACCTTGTATCACTTGGGCAGATAATCGTAGTGAGGCATG
GGCACATAAAATCAAAGATGAACTGAATGGCCATGCAGTTTATAGACGAACAGGAACACCTATTCACCCAATGTCACCAT
TAAGTAAAATTACATGGATCGTGAATGATCATCCGGAAATTGCGATTAGAACGAAAAAATATATTGGAATCAAAGAATAT
ATCTTCAAACAATTCTTTGATCAATATGTTGTTGATCATTCCATCGCCTCGTGCATGGGGATGATGAACTTAAAAAAACT
AGGTTGGGATGAGGAAGCTTTAAAAATTGCTGGTATAACATCAAGTCAATTATCTGAACTCGTACCGACCACCCAAACAT
TTAGCAACTGCAATCCAGATTTAGCCCAAAAGATTGGTATCGATTCCCAAACACCGTTTGTCATTGGTGCTAGTGACGGG
GTGCTTTCTAATCTAGGTGTGAATGCAATTCGAAAAGGTGAGATTGCTGTCACAATTGGAACAAGTGGTGCTATTCGGAC
CATCATTGATAAACCACAAACAGATAAAAAAGGAAGAATATTTTGTTATGCCTTAACGGAAAAGCATTGGGTAATTGGTG
GACCGGTAAACAATGGAGGAATGGTCCTTCGTTGGATTCGTGATGAACTTGCTTCATCAGAAGTAGAAACTGCGAAAAGA
CTAGGAATTGATCCATACGATGTATTAACTAAAATAGCTGAACGCGTGAGACCTGGTGCAGACGGATTATTATTCCATCC
ATACCTCGCAGGGGAACGTGCACCATTATGGAATCCAGATGTACGTGGTTCCTTCTTCGGTTTAACGATGTCACATAAGA
AGGAACATATGATTCGTGCAGCTTTAGAAGGCGTTATATATAATTTATACACTGTATTTTTAGCATTAACAGAATGCATG
GATGGTCCTGTAACTCGTATTCAAGCAACAGGCGGCTTCGCAAGGTCTGACGTTTGGCGACAGATGATGTCCGATATTTT
CGCATCTGAAGTCGTTGTTCCAAAGAGCTACGAAAGCTCTTGTCTAGGTGCATGTATATTAGGTCTCTATGCCACAGGAA
AAATTGATTCTTTTGAAATCGTTTCCGAAATGGTTGGCAGTACCTACAAACATACACCGAAAGAAGAAGCAACAAAAGAA
TACAGACAATTACTGCCTATATTTATTAACCTATCAAGGGCGCTAGAAGACGATTATACACGAATTGCAAATTATCAAAG
AAATTTAATAAAGTAA

Upstream 100 bases:

>100_bases
ATGATTGAGGCCTTACATCAAAACTTTGATGATGTTCAAGGGAAAGTCGAAGACCTCTGGATGTCACAACAAATGTTATC
TAAAGGAGTTGAGCAAGGAC

Downstream 100 bases:

>100_bases
AACTTTCATCAGTAATCTCCCATGCCTCGCTTCTATCTAAATCTCGAGGTGGTGGGGGCCTTACTGCCCACGAATAGCGG
GATCAATACAAATACAGCTA

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 511; Mature: 510

Protein sequence:

>511_residues
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAM
HSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNDHPEIAIRTKKYIGIKEY
IFKQFFDQYVVDHSIASCMGMMNLKKLGWDEEALKIAGITSSQLSELVPTTQTFSNCNPDLAQKIGIDSQTPFVIGASDG
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
YRQLLPIFINLSRALEDDYTRIANYQRNLIK

Sequences:

>Translated_511_residues
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAM
HSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNDHPEIAIRTKKYIGIKEY
IFKQFFDQYVVDHSIASCMGMMNLKKLGWDEEALKIAGITSSQLSELVPTTQTFSNCNPDLAQKIGIDSQTPFVIGASDG
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKR
LGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECM
DGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
>Mature_510_residues
SSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAMH
SVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAVYRRTGTPIHPMSPLSKITWIVNDHPEIAIRTKKYIGIKEYI
FKQFFDQYVVDHSIASCMGMMNLKKLGWDEEALKIAGITSSQLSELVPTTQTFSNCNPDLAQKIGIDSQTPFVIGASDGV
LSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRL
GIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMD
GPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEY
RQLLPIFINLSRALEDDYTRIANYQRNLIK

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=473, Percent_Identity=22.1987315010571, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI189409120, Length=470, Percent_Identity=22.5531914893617, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4504007, Length=470, Percent_Identity=22.5531914893617, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI41393575, Length=448, Percent_Identity=21.6517857142857, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI18860918, Length=421, Percent_Identity=22.3277909738717, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI88196792, Length=326, Percent_Identity=25.4601226993865, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1789987, Length=499, Percent_Identity=26.4529058116232, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787789, Length=509, Percent_Identity=24.75442043222, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1790361, Length=495, Percent_Identity=25.2525252525253, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790005, Length=521, Percent_Identity=23.4165067178503, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789168, Length=481, Percent_Identity=20.3742203742204, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789138, Length=510, Percent_Identity=23.1372549019608, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=463, Percent_Identity=23.3261339092873, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321755, Length=418, Percent_Identity=25.5980861244019, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=24.2105263157895, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24654573, Length=399, Percent_Identity=24.5614035087719, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24655555, Length=472, Percent_Identity=23.9406779661017, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655560, Length=472, Percent_Identity=23.9406779661017, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655570, Length=472, Percent_Identity=23.9406779661017, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655574, Length=472, Percent_Identity=23.9406779661017, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24655565, Length=472, Percent_Identity=23.9406779661017, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24656367, Length=494, Percent_Identity=21.4574898785425, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357867, Length=498, Percent_Identity=21.6867469879518, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24656372, Length=301, Percent_Identity=22.9235880398671, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56876; Mature: 56745

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAIS
CCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NITKQHSDKKPSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAV
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEE
YRRTGTPIHPMSPLSKITWIVNDHPEIAIRTKKYIGIKEYIFKQFFDQYVVDHSIASCMG
EEECCCCCCCCCCHHHEEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKKLGWDEEALKIAGITSSQLSELVPTTQTFSNCNPDLAQKIGIDSQTPFVIGASDG
HHHHHHCCCCHHHEEEECCCHHHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCEEEECCCC
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
MVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAIS
CCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
NITKQHSDKKPSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHAV
HHHHHCCCCCCCEEEHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCEE
YRRTGTPIHPMSPLSKITWIVNDHPEIAIRTKKYIGIKEYIFKQFFDQYVVDHSIASCMG
EEECCCCCCCCCCHHHEEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MMNLKKLGWDEEALKIAGITSSQLSELVPTTQTFSNCNPDLAQKIGIDSQTPFVIGASDG
HHHHHHCCCCHHHEEEECCCHHHHHHHCCCHHHHHCCCHHHHHHCCCCCCCCEEEECCCC
VLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGG
HHHHCCCCCEECCCEEEEECCCCCHHHHHCCCCCCCCCCEEEEEECCCCEEEECCCCCCC
MVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPD
EEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCC
VRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWR
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
QMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKE
HHHHHHHHHCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YRQLLPIFINLSRALEDDYTRIANYQRNLIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]