Click here to switch to the map view.

The map label for this gene is gntR [H]

Identifier: 222093929

GI number: 222093929

Start: 161081

End: 161812

Strand: Direct

Name: gntR [H]

Synonym: BCQ_0185

Alternate gene names: 222093929

Gene position: 161081-161812 (Clockwise)

Preceding gene: 222093928

Following gene: 222093930

Centisome position: 3.09

GC content: 35.25

Gene sequence:

>732_bases
ATGACGAAATCAATGGAATTTCTTTATCCTGAAAAATGGCTTTCAAAAGCTTCTACAGGTGATCGTGTTGCGAGCGAATT
GAGAATGCGCATTATTGCAGGTGCAATTGAAAGCGGTACCATCCTGTCAGAAAATAAAATAGCTGCCGATTTTTCTGTAA
GTCGGTCACCCGTTCGTGAAGCATTAAAATTACTAGCTTCTGAAAATATTATTCGCTTAGAAAGAATGGGCGCAGTTGTC
ATTGGTTTAACCGAGAAAGAAATTGAAGAAATATATGATGTTCGTTTACTTATAGAAACGTTTATCTTTGAGCGACTTGG
AAAGATGGACACAAATGATTTAGTAAGAGAACTAAATAAAATAATGGAAATGATGAAAATCGCCATTAAGTATCATGATT
CTGATGAATTTTCTTATCAAGATCTCTTATTCCATGAAACGATTATTCGAACCATTGAGCATTCCTACATCCTGATGATT
TGGAATAATTTAAAGCCTGTTATGGAAAGCTTAATCCTTTTATCAATGCGTACTCGTTTCAAGGAAAAGTACGAAGATTT
TGAACGGATTATTAAAAATCATGAGCTTTATATAAAAGCAATCGAATCAAAAGATCGAGCCCTCATGATTGAGGCCTTAC
ATCAAAACTTTGATGATGTTCAAGGGAAAGTCGAAGACCTCTGGATGTCACAACAAATGTTATCTAAAGGAGTTGAGCAA
GGACATGAGTAG

Upstream 100 bases:

>100_bases
TCTAATAGAACCAACGCGAACAATAAAAGCGCTTGCATAATTAAAAATCCGAGTTATAATACTTGTATACAAGTATACTT
GATTAACACGAGGTGGATTT

Downstream 100 bases:

>100_bases
CTATATGTTAGGTATAGATATCGGTACAACAAGTACGAAAGCAGTTTTATTTACTGAAAAAGGCGAAGTCATTCAAACCG
AGAATATTGGTTATCCACTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTKSMEFLYPEKWLSKASTGDRVASELRMRIIAGAIESGTILSENKIAADFSVSRSPVREALKLLASENIIRLERMGAVV
IGLTEKEIEEIYDVRLLIETFIFERLGKMDTNDLVRELNKIMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMI
WNNLKPVMESLILLSMRTRFKEKYEDFERIIKNHELYIKAIESKDRALMIEALHQNFDDVQGKVEDLWMSQQMLSKGVEQ
GHE

Sequences:

>Translated_243_residues
MTKSMEFLYPEKWLSKASTGDRVASELRMRIIAGAIESGTILSENKIAADFSVSRSPVREALKLLASENIIRLERMGAVV
IGLTEKEIEEIYDVRLLIETFIFERLGKMDTNDLVRELNKIMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMI
WNNLKPVMESLILLSMRTRFKEKYEDFERIIKNHELYIKAIESKDRALMIEALHQNFDDVQGKVEDLWMSQQMLSKGVEQ
GHE
>Mature_242_residues
TKSMEFLYPEKWLSKASTGDRVASELRMRIIAGAIESGTILSENKIAADFSVSRSPVREALKLLASENIIRLERMGAVVI
GLTEKEIEEIYDVRLLIETFIFERLGKMDTNDLVRELNKIMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMIW
NNLKPVMESLILLSMRTRFKEKYEDFERIIKNHELYIKAIESKDRALMIEALHQNFDDVQGKVEDLWMSQQMLSKGVEQG
HE

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28457; Mature: 28325

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSMEFLYPEKWLSKASTGDRVASELRMRIIAGAIESGTILSENKIAADFSVSRSPVRE
CCCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHCCCCCHHHHHH
ALKLLASENIIRLERMGAVVIGLTEKEIEEIYDVRLLIETFIFERLGKMDTNDLVRELNK
HHHHHHCCCHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMIWNNLKPVMESLILLSMRTRF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHCHHHHHHHHHHHHHHHHH
KEKYEDFERIIKNHELYIKAIESKDRALMIEALHQNFDDVQGKVEDLWMSQQMLSKGVEQ
HHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GHE
CCC
>Mature Secondary Structure 
TKSMEFLYPEKWLSKASTGDRVASELRMRIIAGAIESGTILSENKIAADFSVSRSPVRE
CCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHCCCCCHHHHHH
ALKLLASENIIRLERMGAVVIGLTEKEIEEIYDVRLLIETFIFERLGKMDTNDLVRELNK
HHHHHHCCCHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMIWNNLKPVMESLILLSMRTRF
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHCHHHHHHHHHHHHHHHHH
KEKYEDFERIIKNHELYIKAIESKDRALMIEALHQNFDDVQGKVEDLWMSQQMLSKGVEQ
HHHHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
GHE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]