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The map label for this gene is pabB [H]

Identifier: 222093839

GI number: 222093839

Start: 74436

End: 75833

Strand: Direct

Name: pabB [H]

Synonym: BCQ_0078

Alternate gene names: 222093839

Gene position: 74436-75833 (Clockwise)

Preceding gene: 222093838

Following gene: 222093840

Centisome position: 1.43

GC content: 38.05

Gene sequence:

>1398_bases
ATGCAACGAAGAAAATCTTTAGCGCTTTCTATTCCATATCAGTTAGATTTCTTTAAGCAATATAAATTTCTTTCTAAGGA
TAAACCGCAACATATTTTGTTAGAGAGTGGACGTGGCGGTCGTTATAACATCGTGGGATTAAACCCAGTAGCGGTAATCC
GAGGGAAGGGTGAAACGTTACATATAAGTGAAAGTGGTAAGGAAACAATAAAGCAAGGAAACCCATTAGATTTAATGCAG
GAATATATGGAGCGATGGAAAACGGATTATAATCCGGAATACCCGCCTTTTCAAGGTGGTGCAATTGGTTACTTTAGTTA
TGATTGCATCCGTTATATTGAAAAACTTCCTTCTCTTGCGGAGGATGATATTAATATACCTGATATATTCTTTTTATTAT
TTGATGATGTGTTTGTGTATGATCAAGAAGAAAAAGTATTATGGATTATTACACATTATGTCGATAAGCATGAAGAGGCA
AAAGAGCGATTAAATGAATGGAAGGTTCTTTGGGCGACAGAGGCGCCGGAAGTGACTATACCGTTTGCGTGCCCTGAAAA
GAAAAGTGAAGCAGTTGCTTTTACTGAAGAAAGCTTTATGAAGGCGGTTGAATGTATTCAAGAATATATTGGGGCTGGTG
ATGTGTTCCAAGTAAACTTGTCGACAAGACAAGAAAGAACGTTACAAACACACCCACTAGAAATATATACAAGTCTTCGT
GAAATTAATCCATCTCCATATATGGGTTATTTGGAGCTTGGGGATTTTCAAATTGTTAGTGGATCACCGGAGTTGTTAAT
TAAGAAACAAGGAACTGAAGTAAGTACAAGACCAATTGCTGGAACGAGATCTAGAGGGGCAAATGAGCAAGAGGATGAAG
AATTGGCAAGGGAATTAATTGAGAATGAAAAAGAAAGAGCAGAGCACGTCATGCTTGTAGATTTAGAGCGAAATGATTTA
GGACGTGTTTGTAAATATGGCACTGTAGAAGTAGACGAGTTTATGGTAATTGAGAAATACTCACATGTTATGCATATTGT
TTCTAATGTGCGTGGTGAGGTGGAAGAAGATAAAGATGCTTTCGATTTAGTGAAGGCTGTATTCCCTGGAGGAACAATTA
CGGGTGCTCCGAAAATACGTACGATGGAAATTATTGAAGAATTAGAACCTGTTCGCCGAGGGATTTATACAGGTTCAATC
GGTTGGATCGGTTATTCTGGAGATACAGAATTGAATATTGTAATTAGGACACTTCTTGCTAAAGACGGAAAAGCGCATGT
ACAAGCAGGGGCGGGAATTGTAATTGATTCAAATCCGGAAAATGAATATAAAGAGTCGTTAAAAAAGGCGATTGCTTTAT
GGCGTGCAAAAGAACGTAGTGAAGAAACGGTTAGGTGA

Upstream 100 bases:

>100_bases
TTTTCACTAGCCTTCGAATATAACCCTTCTATATACATAACGAATGTAGCTTGAAGTGGTTAATATAAGAGGGTGGGATA
AAAGAAGACGGGGTGTTGAT

Downstream 100 bases:

>100_bases
GAGAAATGATATTAATGATTGATAATTATGATTCTTTTACATTTAATTTAGTGCAGTTTCTTGGAGAACTTGGACAAGAT
CTTGTTGTTAAACGTAACGA

Product: anthranilate synthase, component i (para-aminobenzoate synthase)

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNIVGLNPVAVIRGKGETLHISESGKETIKQGNPLDLMQ
EYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQEEKVLWIITHYVDKHEEA
KERLNEWKVLWATEAPEVTIPFACPEKKSEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Sequences:

>Translated_465_residues
MQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNIVGLNPVAVIRGKGETLHISESGKETIKQGNPLDLMQ
EYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQEEKVLWIITHYVDKHEEA
KERLNEWKVLWATEAPEVTIPFACPEKKSEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
>Mature_465_residues
MQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNIVGLNPVAVIRGKGETLHISESGKETIKQGNPLDLMQ
EYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDINIPDIFFLLFDDVFVYDQEEKVLWIITHYVDKHEEA
KERLNEWKVLWATEAPEVTIPFACPEKKSEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELIENEKERAEHVMLVDLERNDL
GRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSI
GWIGYSGDTELNIVIRTLLAKDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=428, Percent_Identity=36.6822429906542, Blast_Score=280, Evalue=9e-77,
Organism=Escherichia coli, GI1787518, Length=366, Percent_Identity=38.5245901639344, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1786809, Length=205, Percent_Identity=28.780487804878, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87082077, Length=216, Percent_Identity=24.0740740740741, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=473, Percent_Identity=37.8435517970402, Blast_Score=300, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6324361, Length=402, Percent_Identity=24.8756218905473, Blast_Score=117, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 53148; Mature: 53148

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNIVGLNPVAVIRGKGETL
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISESGKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLA
EECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCC
EDDINIPDIFFLLFDDVFVYDQEEKVLWIITHYVDKHEEAKERLNEWKVLWATEAPEVTI
CCCCCCCHHHHHHHHHHEEEECCCCEEEEEEHHHCCHHHHHHHHHHCEEEEECCCCCEEE
PFACPEKKSEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHH
KDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRRKSLALSIPYQLDFFKQYKFLSKDKPQHILLESGRGGRYNIVGLNPVAVIRGKGETL
CCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCEEEEECCCCEE
HISESGKETIKQGNPLDLMQEYMERWKTDYNPEYPPFQGGAIGYFSYDCIRYIEKLPSLA
EECCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCC
EDDINIPDIFFLLFDDVFVYDQEEKVLWIITHYVDKHEEAKERLNEWKVLWATEAPEVTI
CCCCCCCHHHHHHHHHHEEEECCCCEEEEEEHHHCCHHHHHHHHHHCEEEEECCCCCEEE
PFACPEKKSEAVAFTEESFMKAVECIQEYIGAGDVFQVNLSTRQERTLQTHPLEIYTSLR
EECCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHCCCCHHHHHHHH
EINPSPYMGYLELGDFQIVSGSPELLIKKQGTEVSTRPIAGTRSRGANEQEDEELARELI
HCCCCCCEEEEEECCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNVRGEVEEDKDA
HCHHHHCCEEEEEEECCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDTELNIVIRTLLA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHH
KDGKAHVQAGAGIVIDSNPENEYKESLKKAIALWRAKERSEETVR
CCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]