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The map label for this gene is dppA [H]

Identifier: 221636311

GI number: 221636311

Start: 886905

End: 887660

Strand: Reverse

Name: dppA [H]

Synonym: trd_A0904

Alternate gene names: 221636311

Gene position: 887660-886905 (Counterclockwise)

Preceding gene: 221636312

Following gene: 221636308

Centisome position: 96.72

GC content: 66.67

Gene sequence:

>756_bases
ATGGAGCTCGTCATCGTCGCTGACCTGGAGGGAATGTCCGGTGTCGCTGAGCGAGCCTGGTGCGATCCAGCTCGTCCGGA
GTACGCGCGCGCCCTCGAGCAGTACGCAGAGGACGTGCGCGCGGTGAGCCAGGCCGCTCGCGCTTTCGGGATCGCGCGTA
TTCGCCTTCTCGATTGGCACGGACGCGCTATTCCACCCAGCCTGTGTACCAGTGACATCGAGCCTGCGCTGCTCCCGCTC
GACCGAAACCCGCGCTTGGCGGTCCTGTTGGGTTTTCACGCCCGCGGCGACGCTCCTCGTGCTTTCGCCCCCTGCACCCT
TCTTCCCGGACTGTCCATCGAGTGGGATGGTCGACCAGCTGGGGAACTCGCGCTCGCCAGTCGTTGGCTCGGTGAGCAGG
GTATCCCGCTCCTGCTCGTCTCCGGAGACCGCGCGCTGACCGCGGAAGCTGAACTCTGGACCGATCAGACGACAGCCATC
GCCGTGAAACTGGCTCACTCCCCGGATCGAGCGGAGTGTCTTCCACCGGATCGTGCCCGGGCTGCGCTCGTCGACGCGCT
GCAGCGTGTCCTCGCGCGCCGCTCCTGGTGGTGGGTCTACCGGCCGTCCTCACCGATCGATGTCACCGTGAGCCTGCCTG
CGGGCGGTCAGGAGCGTCTGGTCGCATCGTCCATGAACGAGCTCTTCGTTCAACTGGATAGGCTCGTTGCTCGGGCGGGC
GGCATCCCCACCCTCGCTCGGCTCGCGTCATCATGA

Upstream 100 bases:

>100_bases
TCGACCCTTCTCGTCGGCTCTCCTTCGCTTCGTCGATCGCCTTTCGCCGGCCTCGCCGGTATGCTTGCCCTCGATCGGTC
AGTGATTCTGCGGAGGTCGA

Downstream 100 bases:

>100_bases
GTCGTCCGTCCCGAAGCCGCGCTCCTCGAGCTCGGCCAGCAGTCGCTGGATCGCCGGGGGAAGTTCGGTCGCTGTCTCGT
CGCTCGCGTTCTCAGCGCGC

Product: D-aminopeptidase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MELVIVADLEGMSGVAERAWCDPARPEYARALEQYAEDVRAVSQAARAFGIARIRLLDWHGRAIPPSLCTSDIEPALLPL
DRNPRLAVLLGFHARGDAPRAFAPCTLLPGLSIEWDGRPAGELALASRWLGEQGIPLLLVSGDRALTAEAELWTDQTTAI
AVKLAHSPDRAECLPPDRARAALVDALQRVLARRSWWWVYRPSSPIDVTVSLPAGGQERLVASSMNELFVQLDRLVARAG
GIPTLARLASS

Sequences:

>Translated_251_residues
MELVIVADLEGMSGVAERAWCDPARPEYARALEQYAEDVRAVSQAARAFGIARIRLLDWHGRAIPPSLCTSDIEPALLPL
DRNPRLAVLLGFHARGDAPRAFAPCTLLPGLSIEWDGRPAGELALASRWLGEQGIPLLLVSGDRALTAEAELWTDQTTAI
AVKLAHSPDRAECLPPDRARAALVDALQRVLARRSWWWVYRPSSPIDVTVSLPAGGQERLVASSMNELFVQLDRLVARAG
GIPTLARLASS
>Mature_251_residues
MELVIVADLEGMSGVAERAWCDPARPEYARALEQYAEDVRAVSQAARAFGIARIRLLDWHGRAIPPSLCTSDIEPALLPL
DRNPRLAVLLGFHARGDAPRAFAPCTLLPGLSIEWDGRPAGELALASRWLGEQGIPLLLVSGDRALTAEAELWTDQTTAI
AVKLAHSPDRAECLPPDRARAALVDALQRVLARRSWWWVYRPSSPIDVTVSLPAGGQERLVASSMNELFVQLDRLVARAG
GIPTLARLASS

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 27263; Mature: 27263

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVIVADLEGMSGVAERAWCDPARPEYARALEQYAEDVRAVSQAARAFGIARIRLLDWH
CEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
GRAIPPSLCTSDIEPALLPLDRNPRLAVLLGFHARGDAPRAFAPCTLLPGLSIEWDGRPA
CCCCCHHHHCCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCCCC
GELALASRWLGEQGIPLLLVSGDRALTAEAELWTDQTTAIAVKLAHSPDRAECLPPDRAR
HHHHHHHHHCCCCCCEEEEEECCCEEEEHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHH
AALVDALQRVLARRSWWWVYRPSSPIDVTVSLPAGGQERLVASSMNELFVQLDRLVARAG
HHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GIPTLARLASS
CCHHHHHHHCC
>Mature Secondary Structure
MELVIVADLEGMSGVAERAWCDPARPEYARALEQYAEDVRAVSQAARAFGIARIRLLDWH
CEEEEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECC
GRAIPPSLCTSDIEPALLPLDRNPRLAVLLGFHARGDAPRAFAPCTLLPGLSIEWDGRPA
CCCCCHHHHCCCCCCCEEECCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEEECCCCC
GELALASRWLGEQGIPLLLVSGDRALTAEAELWTDQTTAIAVKLAHSPDRAECLPPDRAR
HHHHHHHHHCCCCCCEEEEEECCCEEEEHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHH
AALVDALQRVLARRSWWWVYRPSSPIDVTVSLPAGGQERLVASSMNELFVQLDRLVARAG
HHHHHHHHHHHHHCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GIPTLARLASS
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]