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The map label for this gene is 221636019

Identifier: 221636019

GI number: 221636019

Start: 603830

End: 604933

Strand: Reverse

Name: 221636019

Synonym: trd_A0613

Alternate gene names: NA

Gene position: 604933-603830 (Counterclockwise)

Preceding gene: 221636020

Following gene: 221636014

Centisome position: 65.92

GC content: 62.59

Gene sequence:

>1104_bases
ATGACTGATCCGCGGATCGCCAAATGGGCACGAGTGCTCGTGGACTACTCGCTCGCGGTGCAACCAGAACAGCTCGTCGT
GATCGGGGGAACGCCGCTCGCTGCTCCCTTGATCCGCGAGGTCTATCGCCTCGTGCTGGAACGGGGTGCTCATCCGGTCG
TGCAGGTCGCGCTGCCGGGACTCGCTGAAATCATGTTCCGCGTGGCGAACGACCAGCAACTCACGTTCGTGTCACCGGAC
GAGCGACTGGGGCCGGAGCAGGCTGATGCGCTCTTGCGTATCCTGAGCGAGAGCAACACCAAGGCGTTGACCGGGGTCGA
TCCAGCTCGCCAGCAGCTGCACCAACGGGCACGGACGGAACTGCGTCAGACCTACCTCGAGCGGGCAGCTGCTGGGAAGC
TGGCCTGGTGCGTGACGCTCTATCCGACCGAGGCGTATGCGCAGGACGCGGAAATGGCGCTCGCCGAATACGAAGAGTTC
GTCCTGCGGGCCGGCTTCCTCGATCGGGAGGACCCGGTAACGGCCTGGCGGGAGCAGTCGCGCGAGCAAGCGCGTATCAT
CGACTGGCTCGCGGACAAACGGGAAATTCACGTGCGGGCACCAGATACCGATCTCCGCTTGTCGATCGCTGGACGACGCT
TCGTGAATGCCGATGGACGAAAGAACTTCCCCGACGGTGAGATCTTCACTGGGCCGGTCGAGGATTCCGTGGAAGGGACG
ATCCGCTTCAGTTATCCGTCGATGGTGCAGGGGCGGCAGGTCGAGGATATCCGGCTGTGGTTCGAAGGAGGCCGAGTCGT
CAAGGCGACGGCGGCGCGGAATGAGGCGTTCTTGCATCGCATGCTGGAAACCGATGAGGGGGCACGCCTCGTCGGCGAGT
TCGCCTTTGGGCTCAACCGATCGATTACCCGCTTCACCGGGAACATCTTGTTCGACGAAAAGATCGGGGGAACGCTCCAC
TTGGCGATCGGTGCTGGCTATCCCGAAACCGGGAGTCGCAACCGCTCGGCGGTGCACTGGGACATGATTTGCGATCTGCG
GCGAGACAGCGAAGTGTGGGTCGATGGCCAGCTGTTCATGAAGGACGGAGAAATCCTGATCTAA

Upstream 100 bases:

>100_bases
GCAGGTTCGATCGGTGGTGCGAGGGAGGGGTAGCGTTGGCACGAGTGGGGACAAGGAACCTCCAGGCATTGTAGGATGCG
CAGATGGAAGGAGGCGCGCG

Downstream 100 bases:

>100_bases
TCTAATTGAGCGAGGCAACCGCAACCGGCTGGCCGTTCGGACTGGTCGCCTGCGCGTTGGTCTCGAGCGTGATCGCGAGG
GCATCGTAGAGACGAAGCGG

Product: peptidase M29 aminopeptidase II

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTDPRIAKWARVLVDYSLAVQPEQLVVIGGTPLAAPLIREVYRLVLERGAHPVVQVALPGLAEIMFRVANDQQLTFVSPD
ERLGPEQADALLRILSESNTKALTGVDPARQQLHQRARTELRQTYLERAAAGKLAWCVTLYPTEAYAQDAEMALAEYEEF
VLRAGFLDREDPVTAWREQSREQARIIDWLADKREIHVRAPDTDLRLSIAGRRFVNADGRKNFPDGEIFTGPVEDSVEGT
IRFSYPSMVQGRQVEDIRLWFEGGRVVKATAARNEAFLHRMLETDEGARLVGEFAFGLNRSITRFTGNILFDEKIGGTLH
LAIGAGYPETGSRNRSAVHWDMICDLRRDSEVWVDGQLFMKDGEILI

Sequences:

>Translated_367_residues
MTDPRIAKWARVLVDYSLAVQPEQLVVIGGTPLAAPLIREVYRLVLERGAHPVVQVALPGLAEIMFRVANDQQLTFVSPD
ERLGPEQADALLRILSESNTKALTGVDPARQQLHQRARTELRQTYLERAAAGKLAWCVTLYPTEAYAQDAEMALAEYEEF
VLRAGFLDREDPVTAWREQSREQARIIDWLADKREIHVRAPDTDLRLSIAGRRFVNADGRKNFPDGEIFTGPVEDSVEGT
IRFSYPSMVQGRQVEDIRLWFEGGRVVKATAARNEAFLHRMLETDEGARLVGEFAFGLNRSITRFTGNILFDEKIGGTLH
LAIGAGYPETGSRNRSAVHWDMICDLRRDSEVWVDGQLFMKDGEILI
>Mature_366_residues
TDPRIAKWARVLVDYSLAVQPEQLVVIGGTPLAAPLIREVYRLVLERGAHPVVQVALPGLAEIMFRVANDQQLTFVSPDE
RLGPEQADALLRILSESNTKALTGVDPARQQLHQRARTELRQTYLERAAAGKLAWCVTLYPTEAYAQDAEMALAEYEEFV
LRAGFLDREDPVTAWREQSREQARIIDWLADKREIHVRAPDTDLRLSIAGRRFVNADGRKNFPDGEIFTGPVEDSVEGTI
RFSYPSMVQGRQVEDIRLWFEGGRVVKATAARNEAFLHRMLETDEGARLVGEFAFGLNRSITRFTGNILFDEKIGGTLHL
AIGAGYPETGSRNRSAVHWDMICDLRRDSEVWVDGQLFMKDGEILI

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 41347; Mature: 41215

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPRIAKWARVLVDYSLAVQPEQLVVIGGTPLAAPLIREVYRLVLERGAHPVVQVALPG
CCCCHHHHHHHHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEHHCC
LAEIMFRVANDQQLTFVSPDERLGPEQADALLRILSESNTKALTGVDPARQQLHQRARTE
HHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHH
LRQTYLERAAAGKLAWCVTLYPTEAYAQDAEMALAEYEEFVLRAGFLDREDPVTAWREQS
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
REQARIIDWLADKREIHVRAPDTDLRLSIAGRRFVNADGRKNFPDGEIFTGPVEDSVEGT
HHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCEE
IRFSYPSMVQGRQVEDIRLWFEGGRVVKATAARNEAFLHRMLETDEGARLVGEFAFGLNR
EEECCCCCCCCCCEEEEEEEEECCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
SITRFTGNILFDEKIGGTLHLAIGAGYPETGSRNRSAVHWDMICDLRRDSEVWVDGQLFM
CHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEHHEEECCCCCCEEECCEEEE
KDGEILI
ECCCEEC
>Mature Secondary Structure 
TDPRIAKWARVLVDYSLAVQPEQLVVIGGTPLAAPLIREVYRLVLERGAHPVVQVALPG
CCCHHHHHHHHHHHHHEEECCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEHHCC
LAEIMFRVANDQQLTFVSPDERLGPEQADALLRILSESNTKALTGVDPARQQLHQRARTE
HHHHHHHHCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHH
LRQTYLERAAAGKLAWCVTLYPTEAYAQDAEMALAEYEEFVLRAGFLDREDPVTAWREQS
HHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
REQARIIDWLADKREIHVRAPDTDLRLSIAGRRFVNADGRKNFPDGEIFTGPVEDSVEGT
HHHHHHHHHHCCCCEEEEECCCCCEEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCEE
IRFSYPSMVQGRQVEDIRLWFEGGRVVKATAARNEAFLHRMLETDEGARLVGEFAFGLNR
EEECCCCCCCCCCEEEEEEEEECCEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
SITRFTGNILFDEKIGGTLHLAIGAGYPETGSRNRSAVHWDMICDLRRDSEVWVDGQLFM
CHHHHCCCEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEHHEEECCCCCCEEECCEEEE
KDGEILI
ECCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]