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The map label for this gene is dgoR [H]

Identifier: 221635877

GI number: 221635877

Start: 458931

End: 459743

Strand: Reverse

Name: dgoR [H]

Synonym: trd_A0471

Alternate gene names: 221635877

Gene position: 459743-458931 (Counterclockwise)

Preceding gene: 221635878

Following gene: 221635876

Centisome position: 50.1

GC content: 68.27

Gene sequence:

>813_bases
GTGACGACGGTCGAAGTCCGCAAACTCCCAACTCAGGTCGCGGTCCATCTGGGTCGCGAGCTGATCGCGCTCGCCGGCGA
ACCAGGCGCCGTCTTGCCCTCCGAACAGGAGATTTGCACGCGCTACGGCGTCTCCCGAACGGTCGCCCGCGAGGCGATGC
AACTGCTAGCCGGGCTGGACCTGGTCCGCATCTCCTCGGGTCGCCGCATGGAGTTGCGCCCGCCGCAGGAATGGAACTAC
CTGCACCCGCTCTTGCTCGACATGCTCGACCCCGTCGAAGTCCGGCACCTCCTGGTCGAGCTGCACGACGTCCGGCTCAT
GATCGAGCCAGTGGTCGCAGCGCGAGCCGCCTGCGTCATCGGTCCCGACCAGCTGCACCGCCTGGAGGCGACGCTCGAGG
CGATGCGAGCGCTGGAGAGCGAGCCGGACCGCTACCTCGAGCGCGACCTCGAGTTCCACGCCCAGATCTGCGCGGTCATC
GGCAACCGCGTGCTCGACCGGATCCTGCACGCCTGCCGCTGGCTCCTCATGGCCAGCCGGCGCGTGACCAACCGGCTGTG
GGACTCGCTGGCCAGCGTGACCGACGAGCATCGGGCGATCTATCGCGCCCTAGCCGTGCACGACCCCCAGGCGGCCGAAG
CAGCGATGCGGGCTCATTTGGCCGGCAATGCCCGGGCCTGGTCCCTACCACCCGAGTTGATCGCCGCAGTCCTCGAGCCC
GCTGCTCAATCGGTCCGCGAACGAGTCGCCTCGGGCGTCAACACGCCGATGAGAAAGGGGGGAAGCGACGAGGTGATCGA
AGTCGATCGCTGA

Upstream 100 bases:

>100_bases
CTCCCGGCATCCCGCGCGCGATGCTCGACACGGCCGATGGGGGCTGCTATCATACTGTCGGACAGCTGCCGACCTCACGA
GCCTGCAACGGGAGCCAGGT

Downstream 100 bases:

>100_bases
GCTGGAGCGAAACGCATGGTCGGAGCACGTGAGGAAGGAGGACGGTCACCATGGAACGGAGCACACAGTTCGGTAGCAGC
CAGCAGCTCACGCGGCGCCA

Product: GntR-family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTTVEVRKLPTQVAVHLGRELIALAGEPGAVLPSEQEICTRYGVSRTVAREAMQLLAGLDLVRISSGRRMELRPPQEWNY
LHPLLLDMLDPVEVRHLLVELHDVRLMIEPVVAARAACVIGPDQLHRLEATLEAMRALESEPDRYLERDLEFHAQICAVI
GNRVLDRILHACRWLLMASRRVTNRLWDSLASVTDEHRAIYRALAVHDPQAAEAAMRAHLAGNARAWSLPPELIAAVLEP
AAQSVRERVASGVNTPMRKGGSDEVIEVDR

Sequences:

>Translated_270_residues
MTTVEVRKLPTQVAVHLGRELIALAGEPGAVLPSEQEICTRYGVSRTVAREAMQLLAGLDLVRISSGRRMELRPPQEWNY
LHPLLLDMLDPVEVRHLLVELHDVRLMIEPVVAARAACVIGPDQLHRLEATLEAMRALESEPDRYLERDLEFHAQICAVI
GNRVLDRILHACRWLLMASRRVTNRLWDSLASVTDEHRAIYRALAVHDPQAAEAAMRAHLAGNARAWSLPPELIAAVLEP
AAQSVRERVASGVNTPMRKGGSDEVIEVDR
>Mature_269_residues
TTVEVRKLPTQVAVHLGRELIALAGEPGAVLPSEQEICTRYGVSRTVAREAMQLLAGLDLVRISSGRRMELRPPQEWNYL
HPLLLDMLDPVEVRHLLVELHDVRLMIEPVVAARAACVIGPDQLHRLEATLEAMRALESEPDRYLERDLEFHAQICAVIG
NRVLDRILHACRWLLMASRRVTNRLWDSLASVTDEHRAIYRALAVHDPQAAEAAMRAHLAGNARAWSLPPELIAAVLEPA
AQSVRERVASGVNTPMRKGGSDEVIEVDR

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=222, Percent_Identity=27.027027027027, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48994961, Length=226, Percent_Identity=29.646017699115, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789621, Length=201, Percent_Identity=26.865671641791, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 30140; Mature: 30009

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVEVRKLPTQVAVHLGRELIALAGEPGAVLPSEQEICTRYGVSRTVAREAMQLLAGLD
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCC
LVRISSGRRMELRPPQEWNYLHPLLLDMLDPVEVRHLLVELHDVRLMIEPVVAARAACVI
CEEECCCCEECCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPDQLHRLEATLEAMRALESEPDRYLERDLEFHAQICAVIGNRVLDRILHACRWLLMASR
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVTNRLWDSLASVTDEHRAIYRALAVHDPQAAEAAMRAHLAGNARAWSLPPELIAAVLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAQSVRERVASGVNTPMRKGGSDEVIEVDR
HHHHHHHHHHHCCCCHHHCCCCCCEEECCC
>Mature Secondary Structure 
TTVEVRKLPTQVAVHLGRELIALAGEPGAVLPSEQEICTRYGVSRTVAREAMQLLAGLD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCC
LVRISSGRRMELRPPQEWNYLHPLLLDMLDPVEVRHLLVELHDVRLMIEPVVAARAACVI
CEEECCCCEECCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GPDQLHRLEATLEAMRALESEPDRYLERDLEFHAQICAVIGNRVLDRILHACRWLLMASR
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVTNRLWDSLASVTDEHRAIYRALAVHDPQAAEAAMRAHLAGNARAWSLPPELIAAVLEP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAQSVRERVASGVNTPMRKGGSDEVIEVDR
HHHHHHHHHHHCCCCHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]