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The map label for this gene is nagD [C]

Identifier: 221635864

GI number: 221635864

Start: 445709

End: 446485

Strand: Reverse

Name: nagD [C]

Synonym: trd_A0458

Alternate gene names: 221635864

Gene position: 446485-445709 (Counterclockwise)

Preceding gene: 221635867

Following gene: 221635856

Centisome position: 48.65

GC content: 66.28

Gene sequence:

>777_bases
ATGCGAACCATCAGCGGATTCCTTCTCGATGTCGACGGTGTCCTGCACATCGATGGTGAACCGATCCCCGGTGCCGTCCA
GGCAGTGCTCGAGCTGCGCGCCCGGGGCATCCCCTTCGTCCTCCTCACCAACACTACGATACGGACGCGCCGACAGCTGG
GTGCCCTGCTCCGCGAACTCGGCTTCCCCGTCGCCGATGACGAGATCGTGACGGCCGGCGCAGCGACTGCAGCATACCTG
CGTGCTCACTACCCTGGCGAGCCCTGCTACCTCTTGGTCGACGGTGACGTGCAGGAAGAGTTCGCCGGTATCCCACTGGT
CGAGGATGACAGCGCGACTGTTGTCGTCTTCGGTGGCGCTGGTCCCGTCTACAGCTACGATCGCCTCAACCGCGCGTTCC
GTTTGTTGCTCCGCGGCGCCCATTTCGTCGCCATGCACCGTAACCTGGTCTGGGATCGCCGCGATGGCCCGGCACTCGAT
ACCGGCGCCTTTCTGCTCGGGCTGGAAGCGGCTCTCGGGCGACAGGCGCACCTCGTCGGCAAGCCATCGCCCGACTTCTT
CCGAGCCGGCTTGGAGCGCCTCGGTCTTTCACCGGAGCGCGTGGCCGTGGTGGGCGACAGCCTGGCTGCCGATATCCTCC
CGGCTCGCCAGCTCGGAATGACGGGGGTGCTCGTCCAGACCGGACGTTTCCGCCCCAACGACCTCGAACTGGGGCGACCG
GACGCGCTGCTTCCTTCCATCGCTGAGCTGCCCAGCTGGCTCAGCCGAGCATCGTGA

Upstream 100 bases:

>100_bases
GCACCACCATCGGCGCACCGCTCGGCACTGGATCGCTACACTGTACAGGGGAAGGCGCCGTCCGGCGCTGGAACCCGACC
AGCTCGGTGGAGACGATGCG

Downstream 100 bases:

>100_bases
GGCGCGAGACCCCCTTACCACCCGGAACGACGCTTCCTCTCCAGGATCGCGGCGAAGCGAGCACGCGCCTCAGGCGCCCG
CTGCTGTCGCGCTGCGGAGC

Product: HAD-superfamily subfamily IIA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MRTISGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLRELGFPVADDEIVTAGAATAAYL
RAHYPGEPCYLLVDGDVQEEFAGIPLVEDDSATVVVFGGAGPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALD
TGAFLLGLEAALGRQAHLVGKPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDLELGRP
DALLPSIAELPSWLSRAS

Sequences:

>Translated_258_residues
MRTISGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLRELGFPVADDEIVTAGAATAAYL
RAHYPGEPCYLLVDGDVQEEFAGIPLVEDDSATVVVFGGAGPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALD
TGAFLLGLEAALGRQAHLVGKPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDLELGRP
DALLPSIAELPSWLSRAS
>Mature_258_residues
MRTISGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLRELGFPVADDEIVTAGAATAAYL
RAHYPGEPCYLLVDGDVQEEFAGIPLVEDDSATVVVFGGAGPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALD
TGAFLLGLEAALGRQAHLVGKPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDLELGRP
DALLPSIAELPSWLSRAS

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI14149777, Length=239, Percent_Identity=36.8200836820084, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI269847098, Length=237, Percent_Identity=32.0675105485232, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI269847104, Length=199, Percent_Identity=31.6582914572864, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI108796653, Length=291, Percent_Identity=29.553264604811, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI10092677, Length=248, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1786890, Length=252, Percent_Identity=32.9365079365079, Blast_Score=117, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17557870, Length=239, Percent_Identity=34.7280334728033, Blast_Score=130, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17562356, Length=238, Percent_Identity=34.0336134453782, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI19920940, Length=254, Percent_Identity=35.0393700787402, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI24666137, Length=293, Percent_Identity=29.0102389078498, Blast_Score=80, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00702 Hydrolase; PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 27779; Mature: 27779

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTISGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLREL
CCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
GFPVADDEIVTAGAATAAYLRAHYPGEPCYLLVDGDVQEEFAGIPLVEDDSATVVVFGGA
CCCCCCCCEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCCEEECCCCEEEEECCC
GPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALDTGAFLLGLEAALGRQAHLVG
CCCCCHHHHHHHHHHHHHCHHHEEEHHHHEEECCCCCCCCCCHHHHHHHHHHCCCEEECC
KPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDLELGRP
CCCHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
DALLPSIAELPSWLSRAS
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTISGFLLDVDGVLHIDGEPIPGAVQAVLELRARGIPFVLLTNTTIRTRRQLGALLREL
CCCCCCEEEEECCEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
GFPVADDEIVTAGAATAAYLRAHYPGEPCYLLVDGDVQEEFAGIPLVEDDSATVVVFGGA
CCCCCCCCEEECCHHHHHHHHHCCCCCCEEEEEECCHHHHHCCCCEEECCCCEEEEECCC
GPVYSYDRLNRAFRLLLRGAHFVAMHRNLVWDRRDGPALDTGAFLLGLEAALGRQAHLVG
CCCCCHHHHHHHHHHHHHCHHHEEEHHHHEEECCCCCCCCCCHHHHHHHHHHCCCEEECC
KPSPDFFRAGLERLGLSPERVAVVGDSLAADILPARQLGMTGVLVQTGRFRPNDLELGRP
CCCHHHHHHHHHHHCCCCHHEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCC
DALLPSIAELPSWLSRAS
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631946 [H]