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The map label for this gene is comM [H]

Identifier: 221635423

GI number: 221635423

Start: 14959

End: 16476

Strand: Reverse

Name: comM [H]

Synonym: trd_A0017

Alternate gene names: 221635423

Gene position: 16476-14959 (Counterclockwise)

Preceding gene: 221635424

Following gene: 221635422

Centisome position: 1.8

GC content: 68.84

Gene sequence:

>1518_bases
GTGCTCGCCTGTGTCCACAGCTCGGCGGTCGTCGGCCTGGAAGGGGTGCTGGTCGAAGTCGAGGTCGACATCGGGCCGGG
TAATCCCGGCTTGACCATCGTCGGCCTGCCGGACGCCGCTGTCCAGGAGGCGCGCGAGCGCGTCCGCGCAGCGATCCGCA
ACAGCGGGGCGCGCTTTCCGCTGAGCGGTCGCATCACCGTCAATCTCGCTCCCGCCGATATCCGCAAGGAGGGACCGGCG
TACGACCTTCCCATCGCGCTCGGTATCTTGCTGGCGAGCGGGCAGGTCAGTGCCGATCTCACCGATACGGTCGTGCTGGG
CGAGCTCTCGCTCGACGGGACGGTGCGTCATACCGCTGGTATCCTGCCGATGGTCGGTATCGCCCGCGAGCACGGGCTGC
GTCGCGCCATCGTCCCCGCTGAGGACGCAGCCGAGGCCGCGCTGGTCGAGGGGATCGAAGTGATCCCCGTCCAGAGCTTG
AACGAACTTCTCGCGCATCTCGACGGTCAGGCACCGATCGCCCCGCTCCCGCCGACGCCGATCGAGCTGGGTGACGAGCC
GCTGAGCGGGATCGATTTCGCGGAGATCAAAGGACAAGAGCACGTCAAGCGCGGGCTGGAACTGGCAGCAGCTGGCGGAC
ATAACGTCATCGCCGTCGGACCTCCCGGTGCCGGCAAGACACTTCTGGCTCGCGCCTTGCCGACCATTCTTCCGCCGCTC
ACCCGTGAGGAGGCGCTCGAGGTCACTCGCATCTACTCGGTCGCCGGGCTGCTCCCCAGCGGATCACCGCTCATCCGCCA
CCGACCGTTCCGCGCACCGCACCATACGATCAGCTTCGCCGGCATGATCGGTGGTGGTGCCTGGCCCCGGCCCGGCGAGG
TGACGCTGGCACACCGTGGAGTCCTCTTCCTCGACGAGTTGCCCGAGTTCAGCCCGCGGGTCCTCGAGGTCCTTCGCCAG
CCGCTCGAGGACCGCCTCGTCACCATCTCGCGCGCCAGTGGCGCCGTCACCTTCCCGGCCTCGTTCTTGCTCGTTGCCGC
CATGAATCCCTGTCCCTGCGGCTACCACGGCGACCCGGTTCGCGCCTGCCGGTGCAGCCCTCACGAGGTCGCGCGCTACC
AGAAGCGGATCTCCGGTCCCCTGCTCGACCGCATCGATATTCACCTGCCTGTCCCGCGCGTCGAGTTCGACAAGCTGGCC
GACCACCGGACCGGAGAGCCCTCCGCGGCGGTCCGGGCTCGCGTCGAAGCCGCCCGAGCCGTGCAACAGCTCCGCTTCGG
CGATTCGCGGCGACTCAACAGCGAGATGACCCCGGCCGAGATCCGTCGGTACTGCCGGTTGGACGAGGCGGGCGAGCGCT
TACTCCGTACGGCAGTTGAGCGGCTGGGGCTCTCGGCGCGGGGATATCACCGCGTCCTCAAGCTCGCGCGGACGATCGCT
GATCTCGCTGGCGCGGAGCGGATCGCCGCCGTTCACGTCGCCGAAGCGCTCCAGTACCGGCCGCAGGAGGTCGGCTGA

Upstream 100 bases:

>100_bases
CGCCGTCTATCCACCCCCATCTGACCGTCCTTCTCCAGGGGCCGACCAGGCAGTAGAATGAGCGTCGTGTCGGCTCGGTT
CCGGAACGAGAGGAGTTCGC

Downstream 100 bases:

>100_bases
TCGCCTGGTCGCAGTACGTTGGCTCCCGGCTCGCACCACCTCGCGAACGCCGTCGGCGTCGACCCGCTGCGCATCGTGAG
CGGCCCCGGCGAGGAGCGAC

Product: putative Mg chelatase homolog

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MLACVHSSAVVGLEGVLVEVEVDIGPGNPGLTIVGLPDAAVQEARERVRAAIRNSGARFPLSGRITVNLAPADIRKEGPA
YDLPIALGILLASGQVSADLTDTVVLGELSLDGTVRHTAGILPMVGIAREHGLRRAIVPAEDAAEAALVEGIEVIPVQSL
NELLAHLDGQAPIAPLPPTPIELGDEPLSGIDFAEIKGQEHVKRGLELAAAGGHNVIAVGPPGAGKTLLARALPTILPPL
TREEALEVTRIYSVAGLLPSGSPLIRHRPFRAPHHTISFAGMIGGGAWPRPGEVTLAHRGVLFLDELPEFSPRVLEVLRQ
PLEDRLVTISRASGAVTFPASFLLVAAMNPCPCGYHGDPVRACRCSPHEVARYQKRISGPLLDRIDIHLPVPRVEFDKLA
DHRTGEPSAAVRARVEAARAVQQLRFGDSRRLNSEMTPAEIRRYCRLDEAGERLLRTAVERLGLSARGYHRVLKLARTIA
DLAGAERIAAVHVAEALQYRPQEVG

Sequences:

>Translated_505_residues
MLACVHSSAVVGLEGVLVEVEVDIGPGNPGLTIVGLPDAAVQEARERVRAAIRNSGARFPLSGRITVNLAPADIRKEGPA
YDLPIALGILLASGQVSADLTDTVVLGELSLDGTVRHTAGILPMVGIAREHGLRRAIVPAEDAAEAALVEGIEVIPVQSL
NELLAHLDGQAPIAPLPPTPIELGDEPLSGIDFAEIKGQEHVKRGLELAAAGGHNVIAVGPPGAGKTLLARALPTILPPL
TREEALEVTRIYSVAGLLPSGSPLIRHRPFRAPHHTISFAGMIGGGAWPRPGEVTLAHRGVLFLDELPEFSPRVLEVLRQ
PLEDRLVTISRASGAVTFPASFLLVAAMNPCPCGYHGDPVRACRCSPHEVARYQKRISGPLLDRIDIHLPVPRVEFDKLA
DHRTGEPSAAVRARVEAARAVQQLRFGDSRRLNSEMTPAEIRRYCRLDEAGERLLRTAVERLGLSARGYHRVLKLARTIA
DLAGAERIAAVHVAEALQYRPQEVG
>Mature_505_residues
MLACVHSSAVVGLEGVLVEVEVDIGPGNPGLTIVGLPDAAVQEARERVRAAIRNSGARFPLSGRITVNLAPADIRKEGPA
YDLPIALGILLASGQVSADLTDTVVLGELSLDGTVRHTAGILPMVGIAREHGLRRAIVPAEDAAEAALVEGIEVIPVQSL
NELLAHLDGQAPIAPLPPTPIELGDEPLSGIDFAEIKGQEHVKRGLELAAAGGHNVIAVGPPGAGKTLLARALPTILPPL
TREEALEVTRIYSVAGLLPSGSPLIRHRPFRAPHHTISFAGMIGGGAWPRPGEVTLAHRGVLFLDELPEFSPRVLEVLRQ
PLEDRLVTISRASGAVTFPASFLLVAAMNPCPCGYHGDPVRACRCSPHEVARYQKRISGPLLDRIDIHLPVPRVEFDKLA
DHRTGEPSAAVRARVEAARAVQQLRFGDSRRLNSEMTPAEIRRYCRLDEAGERLLRTAVERLGLSARGYHRVLKLARTIA
DLAGAERIAAVHVAEALQYRPQEVG

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=502, Percent_Identity=44.2231075697211, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 53910; Mature: 53910

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLACVHSSAVVGLEGVLVEVEVDIGPGNPGLTIVGLPDAAVQEARERVRAAIRNSGARFP
CEEEECCCCEEEECEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
LSGRITVNLAPADIRKEGPAYDLPIALGILLASGQVSADLTDTVVLGELSLDGTVRHTAG
CCCEEEEEECCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHC
ILPMVGIAREHGLRRAIVPAEDAAEAALVEGIEVIPVQSLNELLAHLDGQAPIAPLPPTP
CHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
IELGDEPLSGIDFAEIKGQEHVKRGLELAAAGGHNVIAVGPPGAGKTLLARALPTILPPL
CCCCCCCCCCCCHHHHCCHHHHHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCC
TREEALEVTRIYSVAGLLPSGSPLIRHRPFRAPHHTISFAGMIGGGAWPRPGEVTLAHRG
CHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECC
VLFLDELPEFSPRVLEVLRQPLEDRLVTISRASGAVTFPASFLLVAAMNPCPCGYHGDPV
EEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEECHHHHHHHCCCCCCCCCCCCCCC
RACRCSPHEVARYQKRISGPLLDRIDIHLPVPRVEFDKLADHRTGEPSAAVRARVEAARA
CCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
VQQLRFGDSRRLNSEMTPAEIRRYCRLDEAGERLLRTAVERLGLSARGYHRVLKLARTIA
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLAGAERIAAVHVAEALQYRPQEVG
HHHCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLACVHSSAVVGLEGVLVEVEVDIGPGNPGLTIVGLPDAAVQEARERVRAAIRNSGARFP
CEEEECCCCEEEECEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCC
LSGRITVNLAPADIRKEGPAYDLPIALGILLASGQVSADLTDTVVLGELSLDGTVRHTAG
CCCEEEEEECCHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHC
ILPMVGIAREHGLRRAIVPAEDAAEAALVEGIEVIPVQSLNELLAHLDGQAPIAPLPPTP
CHHHHHHHHHCCCCEECCCCCHHHHHHHHCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
IELGDEPLSGIDFAEIKGQEHVKRGLELAAAGGHNVIAVGPPGAGKTLLARALPTILPPL
CCCCCCCCCCCCHHHHCCHHHHHHCCEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCC
TREEALEVTRIYSVAGLLPSGSPLIRHRPFRAPHHTISFAGMIGGGAWPRPGEVTLAHRG
CHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCEEEEEEEECCCCCCCCCCEEEEECC
VLFLDELPEFSPRVLEVLRQPLEDRLVTISRASGAVTFPASFLLVAAMNPCPCGYHGDPV
EEEECCCCCCCHHHHHHHHHHHHHHEEEEECCCCCEECHHHHHHHCCCCCCCCCCCCCCC
RACRCSPHEVARYQKRISGPLLDRIDIHLPVPRVEFDKLADHRTGEPSAAVRARVEAARA
CCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHH
VQQLRFGDSRRLNSEMTPAEIRRYCRLDEAGERLLRTAVERLGLSARGYHRVLKLARTIA
HHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLAGAERIAAVHVAEALQYRPQEVG
HHHCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]